Melissa M. Rhodes, MD

Melissa M. Rhodes, MD, is the Director of the Comprehensive Sickle Cell and Thalassemia Program at Nationwide Children’s Hospital and an Assistant Professor of Pediatrics at The Ohio State University College of Medicine. Her research interests include cardiopulmonary complications, nutrition and growth and development in sickle cell disease. She is also interested in the interactions between developing red blood cells and other cell types in various forms of anemia. Dr. Rhodes is the institutional investigator for national trials in sickle cell disease, including membership in the National Institutes of Health Sickle Cell Disease Clinical Trials Network.

Gender:

• Female

Languages Spoken:

• English

Medical School

• Eastern Virginia Medical School
  Date Completed: 05/31/1999

Residency

• Children's Hospital of the King's Daughters Hospit
  Date Completed: 06/30/2002

Fellowship

• Vanderbilt University School of Medicine
  Date Completed: 06/30/2006

Department:

• Pediatrics

Section:

• Hematology/Oncology

Speciality:

• Pediatric Hematology Oncology, Certified
  
• Pediatrics, Certified
  

Date of Appointment at Children's Hospital:

• 07/01/2008

• Dickerson AK, Klima J, Rhodes MM, O?Brien S. 2011. Young adults with SCD in U.S. children?s hospitals: are they different from adolescents?.  Pediatr Blood Cancer. (July 27)
• Rhodes M, Ashford L, Manes B, Calder C, Domm J, Frangoul H. 2011. Bone marrow transplant in phosphoglycerate kinase deficiency.  British Journal of Haematology. Vol. 152. : 500-502.
• Debaun MR, Sarnaik SA, Rodeghier MJ, Minniti CP, Howard TH, Iyer RV, Inusa B, Telfer PT, Kirby-Allen M, Quinn CT, Bernaudin F, Airewele G, Woods GM, Panepinto JA, Fuh B, Kwiatkowski JK, King AA, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Sabio H, Gonzalez CE, Saccente SL, Kalinyak KA, Strouse JJ, Fixler JM, Gordon MO, Miller JP, Ichord RN, Casella JF. 2011. Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, gender and relative high systolic blood pressure.  Blood.
• Bollinger LM, Nire KG, Rhodes MM, Chisholm DJ, O'Brien SH. 2011. Caregivers perspectives on barriers to transcranial doppler screening in children with sickle cell disease.  Pediatric Blood and Cancer. no. 56. : 99-102.
• Poehling K, Simms L, Rhodes M, Snively B, Halasa N, Mitchel E, Schaffner W, Craig A, Griffin M. 2010. Sickle cell trait, hemoglobin C trait and invasive pneumococcal disease.  Epidemiology. Vol. 3, no. 21: 340-346. 20220521. (Unspecified)
• O?Keeffe E, Rhodes M, Woodworth A. 2009. To C or not to C?Interesting diagnostic challenges of hemoglobinopathies.  Clinical Chemistry. Vol. 55: 1228-1233.
• Rhodes M, Akohoue S, Shankar S, Flemming I, An A, Yu C, Acra S, Buchowski M. 2009. Growth patterns in children with sickle cell anemia during puberty.  Pediatric Blood and Cancer. Vol. 53: 635-641.
• Koury MJ, Mahmud N, Rhodes MM. 2009. Origin and Development of Blood Cells. In Wintrobe?s Clinical Hematology, 12th ed.. 12 ed. Vol. 1. Edited by John Greer. New York, New York: LWW. 79-105.
• Rhodes M, Kopsombut P, Bondurant M, Price J, Koury M. 2008. Adherence to macrophages in erythroblastic islands enhances erythroblast proliferation and increases erythrocyte production by a different mechanism than erythropoietin.  Blood, no. 111: 1700-1708.
• Rhodes M, Miller J, Sipos L, Whitlock J. 2007. ChemoDuck: the creation of an educational tool for young children with cancer.  Supportive and Palliative Cancer Care. Vol. 4, no. 4: 13-16.
• Rhodes M, Delbeke D, Whitlock J, Martin W, Kuttesch J, Frangoul H, Shankar S. 2006. Utility of FDG-PET in follow-up of children treated for Hodgkin?s Non-Hodgkin?s Lymphoma.  Journal of Pediatric Hematology and Oncology, no. 28: 300-306.
• Flanagan J, Rhodes M, Beutler E. 2006. The identification of a recurrent Phosphoglycerate Kinase mutation associated with chronic hemolytic anemia and neurological dysfunction in a family from the USA.  British Journal of Hematology, no. 134: 233-237.
• Rhodes M, Kopsombut P, Bondurant M, Price J, Koury M. 2005. Bcl-xL prevents apoptosis of late-stage erythroblasts but does not mediate the anti-apoptotic effects of erythropoietin.  Blood, no. 106: 1857-1863.
• Rhodes M, Lautz T, Kavanaugh-Mchugh A, Manes B, Calder C, Koyama T, Liske M, Parra D, Frangoul H. 2005. Pericardial effusion and cardiac tamponade in pediatric stem cell transplant recipients.  Bone Marrow Transplant, no. 36: 139-144.
• Guthrie SO, Rhodes M, Janco R, Stein SM, Jabs K, Engelhardt B. 2005. An infant with Kasabach-Merritt syndrome with associated renal hematoma and intussusception.  Journal of Perinatology, no. 25: 143-145.
• Rhodes MM, Presenter. 2006. Aplastic Anemia, MDS, and PNH in Children. Presented at Aplastic Anemia and Myelodysplasia International Family Conference. (August)
• Rhodes MM, Presenter. 2009. Macrophages mediate extrinsic loss of transferrin receptors From circulating reticulocytes. Presented at Red Cell Gordon Conference. (June)
• Rhodes MM, Lecturer. 2003 - 2004. Evaluation of Anemia. Presented at Meharry Medical College Clerkship students. (July - June)
• Rhodes M, Lautz T, Manes B, Calder C, Kavanaugh-Mchugh A, Frangoul H, Poster Presenter. 2005. Pericardial effusion and cardiac tamponade in pediatric stem cell transplant recipients. Presented at American Society of Pediatric Hematology/ Oncology and Pediatric Academic Societies meeting. (May)
• Rhodes MM, Presenter. 2010. Beta Thalassemia, Why is It so Confusing? Presented at Journal Club. (January)
• Rhodes MM, Presenter. 2007. Bone Marrow Transplant in Sickle Cell Disease. Presented at Transplant Journal Club. (August)
• Ralstrom E, daFonseca M, Amini H, Rhodes M, Poster Presenter. 2010. The Impact of Oral Health In Adolescents with Sickle Cell Disease. Presented at American Academy of Dental Research. (April)
• Rhodes MM, Presenter. 2011. The Role of Transfusions in Sickle Cell Disease. to American Red Cross Interfaith Reception. (May)
• Rhodes MM, Presenter. 2006. Non-Hodgkin?s Lymphoma. Presented at Fellows? Conference. (August)
• Rhodes MM, Presenter. 2006. Non-Hodgkin?s Lymphoma. (August)
• Rhodes MM, Presenter. 2006. Phosphoglycerate Kinase Deficiency. Presented at Chief?s Conference. (January)
• Rhodes MM, Presenter. 2010. Clinical Research Protocol Conference. (March)
• Rhodes MM, Presenter. 2010. Anesthesia and Sickle Cell Disease. (January)
• Rhodes M, Kopsombut P, Bondurant M, Price J, Koury M, Poster Presenter. 2004. Bcl-x prevents the apoptosis of late-stage, hemoglobin-synthesizing erythroblasts, but it does not mediate the anti-apoptotic effect of erythropoietin on early-stage erythroblasts. Presented at American Society of Hematology. (December)
• Rhodes MM, Presenter. 2008. Sickle Cell Disease for Surgeons. (August)
• Rhodes MM, Presenter. 2007. Osteosarcoma in Children. Presented at Chief?s Conference. (May)
• Rhodes MM, Lecturer. 2011. Sickle Cell Disease and Dentistry: What Every Dentist Should Know. (May)
• Rhodes MM, Discussant. 2005. Spherocytosis, and PGK Deficiency. Presented at Internal Medicine Chief?s Conference for PNH. (October - December)
• Rhodes MM, Presenter. 2006. Hypercalcemia in Pediatric Oncology Patients. Presented at Chief?s Conference. (January)
• Audino A, Cua C, Tang L, Barry N, Cismowski M, Rhodes M, Poster Presenter. 2010. Prognostic value of pro-BNP and VEGF in children with sickle cell disease. Presented at American Society of Pediatric Hematology/ Oncology and Pediatric Academic Societies meeting. (April)
• Rhodes MM, Presenter. 2005. Abdominal Tumors in Children. Presented at Williamsburg Pediatric Conference. (November)
• Rhodes MM, Presenter. 2010. Sickle Cell Disease and Lung Function: Pulmonary Fellow?s Conference. (April)
• Rhodes MM, Presenter. 2008. Acute Chest Syndrome. Presented at Chief?s Conference. (May)
• Rhodes M, Flanagan J, Beutler E, Poster Presenter. 2006. Phosphoglycerate kinase deficiency associated with hemolytic anemia and neurologic dysfunction: a recurrent genetic mutation. Presented at American Society of Pediatric Hematology/ Oncology and Pediatric Academic Societies meeting. (April)
• Rhodes MM, Presenter. 2009. Jehovah?s Witness Families and Blood Conservation. Presented at Diversity Education at Nationwide Children's Hospital. (August)
• Rhodes MM, Presenter. 2010. Predicting Cardiac and Pulmonary Complications in Children With Sickle Cell Disease. Presented at Clinical and Translational Seminar Series, to Nationwide Children's Hospital Research Institute. (May)
• Rhodes MM. 2012. Nationwide Children?s Hospital Pediacast #194 Sickle Cell Anemia: what Parents Ought to Know. (January)
• Rhodes M, Kopsombut P, Price J, Bondurant M, Koury M, Poster Presenter. 2006. Direct interaction with macrophages increases proerythroblasts proliferation while preserving erythropoietin dependence. Presented at American Society of Hematology. (December)
• Rhodes M, Kopsombut P, Price J, Bondurant M, Koury M, Poster Presenter. 2006. Erythroblasts and reticulocytes have specific extracellular interactions during terminal differentiation. Presented at American Society of Pediatric Hematology/ Oncology and Pediatric Academic Societies meeting. (April)
• Rhodes MM, Presenter. 2006. Erythroblast Proliferation: The Island Effect. Presented at Red Cell Club National Meeting. (November)
• Ralstrom E, daFonseca M, Amini H, Rhodes M, Poster Presenter. 2010. The Impact of Oral Health In Adolescents with Sickle Cell Disease. Presented at American Academy of Pediatric Dentistry. (June)
• Rhodes MM, Presenter. 2010. Sickle Cell Disease. Presented at Black History Month Presentation at Nationwide Insurance. (March)
• Rhodes M, Delbeke D, Shankar S, Poster Presenter. 2005. FDG-PET and CT scans in children following treatment of Hodgkin?s Disease and Non-Hodgkin?s Lymphoma. Presented at American Society of Pediatric Hematology/ Oncology and Pediatric Academic Societies meeting. (May)
• Rhodes M, Burke B, Satin-Smith M, Poster Presenter. 2001. Heart rate variability as an indicator of subclinical autonomic neuropathy in children and adolescents with Type I diabetes mellitus. Presented at American Academy of Pediatrics. (October)
• Rhodes M, Kopsombut P, Bondurant M, Price J, Koury M, Poster Presenter. 2004. Bcl-x prevents apoptosis of late-stage erythroblasts but does not mediate the anti-apoptotic effects of erythropoietin. Presented at The Red Cell Club. (October)
• Rhodes MM, Presenter. 2009. Sickle Cell Disease for Surgeons. (August)
• Rhodes MM, Presenter. 2011. Update on Sickle Cell Disease. to Nationwide Children?s Hospital Lounge and Learn. (September)
• Rhodes M, Kopsombut P, Price J, Koury M, Poster Presenter. 2008. Persistence of transferrin receptors on RBCs produced during stress erythropoiesis. Presented at American Society of Hematology. (December)
• Rhodes MM, Presenter. 2006. The Need for Accessory Cells in Erythropoiesis. Presented at Vanderbilt Pediatric Research Conference. (March)
• Rhodes MM, Lecturer. 2003 - 2008. Evaluation of Anemia. Presented at Vanderbilt Medical School Clerkship students. (July - June)
• Rhodes MM, Presenter. 2005. Update on Anemia. Presented at Williamsburg Pediatric Conference. (November)
• Rhodes MM, Presenter. 2007. ITP: Clinical Decision Making in 2007. Presented at Baxter Pharmaceuticals Southeast Educational Conference. (June)