Medical Professional Publications

Innovation and Discovery

(From the October 2014 Issue of MedStat)

More news from The Research Institute can be found at NationwideChildrens.org/Research-Now.

Partial Kidney Removal Unnecessary for Certain Duplex Anomalies
Children with duplex anomalies of the kidney may benefit from a more conservative surgical treatment than partial organ removal, according to a study by first author Daryl McLeod, MD, MPH, urologist at Nationwide Children’s Hospital. The surgical urology team, led by V. Rama Jayanthi, MD, chief of urology at Nationwide Children’s, performed UU surgeries on 41 patients with diagnoses of ureterocele, ectopic duplex ureter and ureteral triplication. Findings from the study, published in the Journal of Pediatric Urology, indicate that ureteroureterostomy (UU) may effectively correct ureteral blockages – sparing children a riskier operation without negatively affecting the lower kidney.

Read the PediatricsOnline article.

Zinc Supplementation Improves Growth in NICU Babies with Chronic Lung Disease
Premature infants with chronic lung disease (CLD) are even more likely than other extremely low birthweight (ELBW) babies to suffer from growth problems and zinc deficiency. In a recent study published in the Journal of Pediatric Gastroenterology and Nutrition, lead author, Ala Shaikhkhalil, MD, a gastroenterologist at Nationwide Children’s Hospital, demonstrated that zinc supplementation is promising for improving growth in ELBW infants with CLD. This retrospective study is one of the first to look at the association between zinc supplementation and growth in ELBW babies with chronic lung disease, also known as bronchopulmonary dysplasia.

Read the Research Now article.

Neuroblastoma Biomarker Predicts Cancer Severity Risk
Neuroblastoma, one of the most common and varied childhood cancers – affecting 8 percent of the pediatric cancer population – has long evaded scientists’ efforts to stratify treatment groups predicted by cancer severity. But a team of scientists from Nationwide Children’s Hospital and collaborating institutions across the country have identified a biomarker in neuroblastoma that helps predict tumor prognosis and potential benefit from aggressive treatment. The study, whose lead author is Nilay Shah, MD, principal investigator in the Center for Childhood Cancer and Blood Diseases in The Research Institute, was published in Clinical Cancer Research in August.

Read the PediatricsOnline article.

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