Perinatal brain injury and subsequent neurodevelopmental impairments occur in over 50% of very preterm infants (1.5% of all births). Preterm births contribute to half of all childhood disabilities and cost the U.S. a minimum of $26 billion annually. Yet, little is known about the causes of injury and few prevention or treatment options exist.
Dr. Nehal Parikh’s group in the Center for Perinatal Research is conducting a longitudinal cohort study in very preterm infants using advanced MRI and EEG to understand the etiology, pathogenesis, and prognosis of perinatal brain injury. The group is also developing imaging biomarkers using novel quantitative MRI post-image processing techniques.
He, L, Parikh NA. Automated White Matter Signal Abnormalities Detection Using T2 Relaxometry: Application to Brain Segmentation on Term MRI in Very Preterm Infants. 2012. Neuroimage. In Press.
Yu X, Zhang Y, Lasky RE, Datta S, Parikh NA, and Narayana PA. Comprehensive Brain MRI Segmentation in High Risk Preterm Newborns. PLoS One. 2010;5: e13874. PMCID: PMC2975631
Contact: Nehal Parikh, DO, MS