Dr. Irina A. Buhimschi most recently was an associate professor of Obstetrics and Gynecology in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale University School of Medicine. Her research interests span the broad area of understanding the molecular and pathophysiologic mechanisms of preterm labor and preeclampsia that together account for the large majority of preterm births.
A central focus of her investigation is related to the discovery of proteomic biomarkers and developing mathematical algorithms to overcome the current syndromic classification of preterm birth. She has discovered several biomarkers that can aid physicians in early diagnosing of preterm birth and preeclampsia to improve neonatal outcome. Other areas of research involve regulation of uterine contractility and cervical ripening, biology of nitric oxide, mechanisms of uterine healing and immunobiology of the amniotic fluid, and placental fetal membranes.
She is currently the co-principal investigator of an RO1 NIH-funded grant aimed toward understanding the role of Receptor for Advanced Glycation End products (RAGE) in fetal damage and in-utero injury. For the last 15 years she has been awarded grant support by the NIH, March of Dimes, Bill and Melinda Gates Foundation and other funding agencies. She has published more than 130 peer-reviewed publications, and has extensive service on editorial boards, including as associate editor for Pediatric Research.
Her husband, Catalin S. Buhimschi, MD, has been appointed Director of Maternal-Fetal Medicine and Vice Chair for Research in the Department of Obstetrics and Gynecology at The Ohio State University.
Dr. Catalin Buhimschi most recently served as Section Chief of the Maternal-Fetal Medicine Division, Director of the Obstetrical Services at Yale-New-Haven-Hospital (YNHH) and Director of Perinatal Research in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale University.
“These new appointments will catalyze our highly productive alliance between The Ohio State University and Nationwide Children’s Hospital, bringing nationally renowned expertise to Columbus and making us a premier location for maternal-fetal medicine and prematurity research in the US,” says John Barnard, MD, president, The Research Institute at Nationwide Children’s.
They will begin their respective appointments in April.