Medical Professional Publications

Innovation and Discovery

(From the October 2017 Issue of MedStat)

Visit NationwideChildrens.org/Research-News for additional information regarding these articles. More news from The Research Institute can be found at NationwideChildrens.org/Research-Now.

Study: Physicians May Be Too Aggressive in Treatment of ITP

When a child presents with easy bruising or bleeding, red skin spots and fatigue – symptoms similar to those for leukemia – families seek evaluation immediately. However, more often these cases are pediatric immune thrombocytopenia (ITP), an acquired disorder that destroys blood platelets and is most common in 2- to 5-year-olds. Historically, the disorder has been treated pharmacologically to increase platelet count until the illness resolves.

In 2011, the American Society of Hematology (ASH) published new treatment guidelines for pediatric ITP that recommended a watchful waiting strategy. A study recently published in Pediatric Blood and Cancer shows that the changes may not have been widely implemented.

Read more in this Pediatrics Nationwide article.

Could Nutritional Supplements Impact Autism Symptoms in Toddlers Born Preterm?

Delay in language development is often an early indicator in children at risk for developing autism spectrum disorder (ASD), yet clinicians are still trying to understand the best practices for how and when to implement early intervention strategies.

A team of researchers at Nationwide Children’s Hospital found in a pilot study, recently published in the Journal of Autism and Developmental Disorders, that supplementation with omega-3 and -6 fatty acids positively effects language development in preterm toddlers at risk for developing ASD.

Read more in this Pediatrics Nationwide article.

Reducing Unnecessary Antibiotic Use for UTI in Urgent Cares

Even before a urine culture confirms the diagnosis, urgent care physicians often prescribe antibiotics when children present with symptoms of urinary tract infection (UTI). A quality improvement project by physician-researchers at Nationwide Children’s Hospital, recently reported in Pediatrics, showed that the implementation of a relatively simple protocol in urgent cares can substantially reduce unnecessary antibiotic exposure after a negative urine culture.

Read more in this Pediatrics Nationwide article.

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