Medical Professional Publications

Innovation and Discovery

(From the April 2017 Issue of MedStat)

More news from The Research Institute can be found at NationwideChildrens.org/Research-News.

New Study Illuminates Issues and Highlights Safe Contraception Options for Women with Diabetes

For women with diabetes, pregnancy planning is critical since hyperglycemia increases the risk for birth defects. However, physicians have been especially reluctant to prescribe hormonal birth control to women with diabetes due to an increased risk of heart attack, stroke and blood clots. A recently published study is one of the first to evaluate hormonal contraception and health outcomes in women with diabetes, showing that although a vast majority did not receive prescription contraception of any kind, strokes and heart attacks are rare for women with diabetes who use hormonal contraception. Sarah O’Brien, MD, principal investigator in the Center for Innovation in Pediatric Practice at The Research Institute and hematologist at Nationwide Children’s Hospital, was lead author of the study.

Read the Pediatrics Nationwide article.

Early Treatment with Heart Failure Medication Improves or Stabilizes Heart Function in Duchenne Muscular Dystrophy

Researchers at Nationwide Children’s Hospital and The Ohio State University Ross Heart Hospital have shown that early treatment with eplerenone can improve heart function in young boys with Duchenne muscular dystrophy and can stabilize heart function in older boys with the neuromuscular disease. Scientists examined the safety and efficacy of longer-term therapy with eplerenone, a diuretic used to treat high blood pressure and heart failure, in eleven boys and young men, ranging from ages 7 to 25 years old, over a two-year period. The study, which was published in Orphanet Journal of Rare Diseases, was led bySubha Raman, MD, cardiologist and professor at Ohio State Wexner Medical Center, and co-authored by Linda Cripe, MD, pediatric cardiologist and investigator at Nationwide Children’s.

Read the News Room article.

Researchers at Nationwide Children’s Hospital and The Ohio State University Collaborate on $2.6M NIH Grant to Study Childhood Obesity Prevention

In order to better understand how parent-child interactions at mealtimes can affect children’s obesity risk, researchers at Nationwide Children’s Hospital and The Ohio State University are teaming up on a four-year, $2.6 million NIH study. Sarah Keim, PhD, principal investigator in the Center for Biobehavioral Health at The Research Institute at Nationwide Children’s, is serving as co-investigator on the study. She is partnering with Sarah Anderson, PhD, associate professor of epidemiology at Ohio State’s College of Public Health, to conduct the new longitudinal study, which will take place at Nationwide Children’s and in the families’ homes. Their hope is that this research will provide more effective childhood obesity prevention strategies, which can also promote young children’s social and emotional development.

Read the Research Now article.

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