(From the October 2016 Issue of MedStat)
Specialized Test Detects Bacterial Infections in Youngest Infants with Fever
Physicians from Nationwide Children’s Hospital, Children’s Hospital of Michigan, and UC Davis Medical Center, in collaboration with 19 other pediatric emergency departments around the country, have established a “proof of principle” for measuring patterns of RNA expression in the bloodstream that can enable clinicians to distinguish bacterial infections from other causes of fevers in infants up to two months old. The diagnostic test has the potential to prevent painful testing, unnecessary antibiotics and hospitalizations for many of the more than 500,000 febrile infants who arrive at hospitals each year. The research, conducted in the Pediatric Emergency Care Applied Research Network (PECARN), was published in the Journal of the American Medical Association and led by principal investigators Octavio Ramilo, MD, at Nationwide Children’s, Prashant Mahajan, MD, MBA, MPH, at Children’s Hospital of Michigan, and Nathan Kuppermann, MD, MPH, at UC Davis Medical Center.
Read the Pediatrics Nationwide article.
$2.5 Million Grant Supports Calcific Aortic Valve Disease Research at Nationwide Children’s Hospital
Calcific aortic valve disease (CAVD) is the most common valvular disorder in developed countries, sending 55,000 patients to the hospital and causing 15,000 deaths annually. The only effective therapy currently available is surgical repair and replacement, which is costly and risky. The National Heart, Lung, and Blood Institute at the National Institutes of Health (NIH) has awarded Vidu Garg, MD, along with Joy Lincoln, PhD, and Brenda Lilly, PhD, in the Center for Cardiovascular Researchin The Research Institute at Nationwide Children’s Hospital a four-year, $2.5 million grant to continue working to identify what causes CAVD.
Read the Research Now article.
New Study Finds Low Transfer Rates of Pediatric Burn Patients in the U.S.
According to a new study from researchers in the Center for Pediatric Trauma Research and the Center for Injury Research and Policy at The Research Institute at Nationwide Children’s Hospital, there is a need for clearer transfer and outpatient referral guidelines for the nearly 189 children per day who have burns that are considered significant injuries by the American Burn Association. Jonathan Groner, MD, pediatric burn surgeon and medical director of the Center for Pediatric Trauma Research, is co-author of the study, which was published online and in the September issue of the journal Burns.
Read the News Room article.