Medical Professional Publications

Innovation and Discovery

(From the May 2015 Issue of MedStat)

Visit NationwideChildrens.org/Research-Newsfor additional information regarding these articles. More news from The Research Institute can be found at NationwideChildrens.org/Research-Now.

No “One-Size-Fits-All” Treatment for Obese Children with Asthma

While a connection between childhood obesity and asthma is well established, there have been few studies to define the biological factors that link the two conditions. A recent study and its accompanying editorial, published in the Journal of Allergy and Clinical Immunology, are now offering insight into how a child’s body weight may deeply impact the way that asthma is experienced – and ultimately managed. David Stukus, MD, an allergy and immunology expert and director of the Complex Asthma Clinic at Nationwide Children’s Hospital, is the author of the study’s editorial.

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Study Finds Cow Milk is Added to Breast Milk and Sold to Parents Online

A Pediatrics study published last month on the safety of human breast milk purchased over the Internet found that 10 percent of samples contained added cow’s milk, confirming a danger for the large number of babies receiving the purchased milk due to medical conditions such as an allergy or intolerance to cow’s milk. Previous research by the same team at Nationwide Children’s Hospital, led by Sarah A. Keim, PhD, principal investigator in the Center for Biobehavioral Health in The Research Institute, identified that these babies are also vulnerable to the risk of infectious disease from bacterial and viral contamination of such milk.

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Transcriptional Profiling: A Promising Tool for Diagnosing Bacterial and Viral Respiratory Infections

Lower respiratory tract infections (LRTIs) are one of the most frequent reasons for hospitalization in adults and children worldwide, but establishing the cause of the infection is challenging in most cases. This leads to unnecessary treatment with antibiotics which facilitates the development of antimicrobial resistance and contributes to increased health care costs. Octavio Ramilo, MD, chief of Infectious Diseases at Nationwide Children’s Hospital, and colleagues from Nationwide Children’s and the University of Rochester, recently published a study in the Journal of Infectious Disease demonstrating that transcriptional profiling can accurately determine whether LRTIs are bacterial or viral in origin.

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