Medical Professional Publications

Featured Clinic: 22q Center Supported by 17 Service Lines

(From the April 2014 Issue of MedStat)

22q11.2 deletion syndrome, also known as DiGeorge Syndrome (DGS), is a relatively common genetic disorder that affects one of every 4,000 children. The syndrome has the potential to impact every system in the body and can therefore lead to a wide-range of health issues including:

  • Feeding difficulties, including nasal regurgitation of food and fluids
  • Hypocalcemia
  • Gastrointestinal problems, including constipation, and GERD
  • Immune system disorders, including frequent infections
  • Kidney disorders
  • ENT problems, including airway problems, laryngeal abnormalities and hearing loss
  • Asymmetric crying facies
  • Cleft palate or submucous cleft palate
  • Orthopedic issues, such as scoliosis, club feet, cervical spine abnormalities
  • Growth problems, sometimes associated with growth hormone deficiency
  • Developmental delays
  • Psychological and/or psychiatric conditions

The Nationwide Children’s 22q Center is run by co-directors Richard Kirschner, MD, and Adriane Baylis, PhD, CCC-SLP, and involves a multidisciplinary team including staff from: Plastic and Reconstructive Surgery, Cardiology, Immunology, Endocrinology, Genetics, Speech-Language Pathology, Developmental Pediatrics, Pediatric Psychology and Neuropsychology, Psychiatry, Gastroenterology, ENT, Rheumatology, Nephrology, Hematology/Oncology, Ophthalmology, Pediatric Dentistry/Orthodontics and Social Work.

To make a referral: All children and adults with 22q deletion syndrome may be referred. Children with atypical deletions and/or duplications may also benefit from evaluation with the 22q Center, depending on their specific needs. To make a referral, call the Plastic Surgery Department at (614) 722-6299.

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000