Mark L. Splaingard, MD

Mark Splaingard, MD, is the Director of the Sleep Disorders Center at Nationwide Children’s Hospital and Professor of Clinical Pediatrics at The Ohio State University College of Medicine. He is board-certified in pediatrics, pediatric pulmonology, physical medicine and rehabilitation and sleep medicine. Dr. Splaingard’s research has concentrated on the outcomes of children with chronic pulmonary and acquired neurological disorders with a recent focus on sleep disorders in children. In 2006, his research projects included studies on a modified smoke alarm to awaken children during slow wave sleep, sleep disorders in children with autism, childhood bipolar disorder, children with obesity and the pathophysiology of aerodigestive reflexes in sleeping infants. In 2006, Dr. Splaingard gave lectures on pediatric sleep medicine to sleep physicians, pediatric residents, pediatric pulmonologists, neonatologists, neurologists, psychiatrists, community pediatricians, nurse practitioners, otolaryngology residents and graduate students at The Ohio State University College of Medicine.

Gender:

• Male

Languages Spoken:

• English

Medical School

• University of Illinois at Chicago
  Date Completed: 06/03/1977

Internship

• Baylor Affiliated Hospitals (Houston)
  Date Completed: 06/30/1978

Residency

• Texas Children's Hospital
  Date Completed: 06/30/1980

Fellowship

• Texas Children's Hospital
  Date Completed: 06/30/1982

Residency

• Baylor Affiliated Hospitals (Houston)
  Date Completed: 08/31/1983

Fellowship

• Children's Memorial Hospital (Chicago)
  Date Completed: 07/31/1999

Department:

• Pediatrics

Section:

• Pulmonary Medicine

Speciality:

• Pediatric Pulmonary Medicine
  
• Pediatrics
  
• Physical Medicine and Rehabilitation
  
• Sleep Medicine
  

Date of Appointment at Nationwide Children’s Hospital:

• 02/27/2004

• Machado RS, Woodley F, Skaggs B, Di Lorenzo C, Splaingard ML, Mousa H. 2012. Gastroesophageal reflux causing sleep interruptions in infants.  J Pediatr Gastoenterol Nutr. Vol. epub, no. November: e..
• Meyer S, Splaingard ML, Repaske D, Zipf W, Atkins J, Jantana K. 2012. Outcomes of upper airway surgery in Prader Willi patients.  Arch Otolaryngol Head Neck Surg. Vol. 138, no. 11. (January): 1047-51.
• Hayes D, Kirkby S, SPLAINGARD ML, Astor T. 2012. Sleep Disordered Breathing after Combined Heart Lung Transplant.  Am J Resp Crit Care Med. Vol. 186, no. (6). (January): 569-70.
• Splaingard ML. . In Sleep Problems in Children.
• *May A, SPLAINGARD ML. Sleep Disturbances. In American Academy of Pediatrics Textbook of Pediatric Care..
• Jadcherla,Sudarshan,R; Parks,Vanessa,N; Peng,Juan; Dzodzomenyo,Samuel; Fernandez,Soledad; Shaker,Reza; Splaingard,Mark. 2012. Esophageal sensation in premature human neonates: temporal relationships and implications of aerodigestive reflexes and electrocortical arousals.  AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. Vol. 302, no. 1. (January): G134-G144.
• Kirkby S, Splaingard ML. ,. In Noisy Breathing in Children Succinct Pediatrics.
• Campbell L, Best J, Khayat R, SPLAINGARD ML. 2012. Issues Applying Math Model to Estimate CPAP Response in CSR.  Am J Respiratory Crit Care Med. Vol. ., no. January: e..
• Kopp B, Hayes D, Ratkiewicz M, Baron N, Splaingard ML. Light and Depression in Cystic Fibrosis.  J Affective Dis.
• Jadcherla SR, Chan CY, Fernandez S, Splaingard ML. Maturation of Upstream and Downstream Esphageal Reflexes in Human Premature Neonates: The Role of Awake and Sleep States.  Amer J Physiology.
• Hayes D, Splaingard ML. . In Sleep Apnea in Adolescents and Adults.
• May A, Splaingard ML. 2011. Central Sleep Apnea. In Common Problems in Rehabilitation Medicine: Pediatrics. Edited by R. Buschbacher & MR Nelson. Philadelphia: Demos.
• Kirkby S, Splaingard ML. 2011. Cystic Fibrosis. In Common Problems in Rehabilitation Medicine: Pediatrics. Edited by R Buschbacher & MR Nelson. London: Demos.
• May A, Splaingard ML. 2011. Obstructive Sleep Apnea. In Common Problems in Rehabilitation Medicine: Pediatrics. Edited by R. Buschbacher & MR Nelson. London: Demos.
• Splaingard, M. 2011. Sleep Disturbances. In American Academy of Pediatrics Textbook of Pediatric Care. Edited by (Authors of book) McInerny, T., Kamat, D.M., Kelleher, K.J., (Editors)Adam, H., Campbell, D, McInerny, T, Adam, H.M.. Elk Grove Village, IL: Americian Academy of Pediatrics.
• Bhattacharjee R; Kheirandish-Gozal L; Spruyt K; Mitchell RB; Promchiarak J; Simakajornboon N; Kaditis AG; Splaingard D; Splaingard M; Brooks LJ; Marcus CL; Sin S; Arens R; Verhulst SL; Gozal D. 2010. Adenotonsillectomy outcomes in treatment of obstructive sleep apnea in children: a multicenter retrospective study.  American Journal Of Respiratory And Critical Care Medicine. Vol. 182, no. 5. (September): e676.
• Hayes D Jr; West SE; Rock MJ; Li Z; Splaingard ML; Farrell PM. 2010. Pseudomonas aeruginosa in children with cystic fibrosis diagnosed through newborn screening: assessment of clinic exposures and microbial genotypes.  Pediatric Pulmonology. Vol. 45, no. 7. (July): e708.
• Lofthouse N; Fristad MA; Splaingard M; Kelleher K; Hayes J; Resko S. 2010. Web-survey of pharmacological and non-pharmacological sleep interventions for children with early-onset bipolar spectrum disorders.  Journal Of Affective Disorders. Vol. 120, no. 1-3. (January): e267.
• Pakalnis A, Splaingard ML, Splaingard D, Kring D, Colvin A. 2009. Serotonin Effects on Sleep and Emotional Disorders in Adolescent Migraines.  Headache. Vol. 49, no. 10. (November): 1486-1492.
• Schechter MS, McColley SA, Silva S, Haselkorn T, Konstan MW, Wagener JS, Investigators and Coordinators of the Epidemiologic Study of Cystic Fibrosis; North American Scientific advisory Group for ESCF. 2009. Association of socioeconomic status with the use of chronic therapies and healthcare utilization in children with cystic fibrosis.  J Pediatr. Vol. 5, no. 155. (November): 634-639.
• Lofthouse N, Gilchrist R, Splaingard M. 2009. Mood-Related Sleep Problems in Children and Adolescents.  Child Adolesc Psychiatr Clin N Am. Vol. 18, no. 4. (October): 893-916.
• Lai HJ, Shoff SM, Farrell PM; Wisconsin Cystic Fibrosis Neonatal Screening Group. 2009. Recovery of Birth Weight z Score Within 2 Years of Diagnosis Is Positively Associated with Pulmonary Status at 6 Years of Age in Children with Cystic Fibrosis.  Pediatrics. Vol. 123, no. 2. (February): 714-722.
• Splaingard, ML. 2009. Sleep Disturbances. In American Academy of Pediatric Textbook of Pediatric Care,. McInerny TK, Adam HM, Campbell DE, Kamat DM, Kelleher KJ ed. Elk Grove Village, Ill: Elsivier.
• Lofthhouse N, Gilchrist N, Splaingard ML. 2009. Sleep and Mood Disorders in Children and Adolescents. In Child Adolescent Psychiatric Clinics of North America. Philadelphia, PA: Elsivier.
• Lofthouse N, Fristad M, Splaingard M, Kelleher K, Hayes J, Resko S. 2008. Web survey of sleep problems associated with early-onset bipolar spectrum disorders.  J Pediatr Psychol. Vol. 33, no. 4. (May): 349-357.
• Splaingard, M. 2008. Sleep Problems in Children with Respiratory Diseases. In Sleep Medicine Clinics: Respiratory Disorders and Sleep. Edited by Magalang, Ulysses. Philadelphia, PA: W.B. Saunders Co, A Division of Elsevier Inc.
• Lofthouse N, Fristad M, Splaingard M, Kelleher K. 2007. Parent and child reports of sleep problems associated with early-onset bipolar spectrum disorders.  Journal of Family Psychology. Vol. 21, no. 1. (January): 114-123.
• Splaingard M, Hayes J, Smith GA. 2007. Impairment of reaction time among children awakened during stage 4 sleep.  Sleep. Vol. 30, no. 1. (January): 104-108.
• Lindstrom DR, Conley SF, Splaingard ML, Gershan WM. 2007. Ibuprofen therapy and nasal polyposis in cystic fibrosis patients.  Journal of Otolaryngology. Vol. 36, no. 5. (January): 309-314.
• Smith GA, Splaingard M, Hayes JR, Xiang H. 2006. Comparison of a personalized parent voice smoke alarm with a conventional residential tone smoke alarm for awakenings children.  Pediatrics. Vol. 118, no. 4. (October): 1623-1632.
• Farrell PM, Lai HJ, Li Z, Kosorok MR, Laxova A, Green CG, Collins J, Hoffman G, Laessig R, Rock MJ, Splaingard ML. 2005. Evidence on improved outcomes with early diagnosis of cystic fibrosis through neonatal screening: enough is enough!.  J Pediatri. Vol. 147, no. 3 Suppl. (September): S30-S36.
• Koscik RL, Douglas JA, Zaremba K, Rock MJ, Splaingard ML, Laxova A, Farrell PM. 2005. Quality of life of children with cystic fibrosis.  J Pediatr. Vol. 147, no. 3 suppl. (September): S64-S68.
• Koscik RL, Lai HJ, Laxova A, Zaremba KM, Kosorok MR, Douglas JA, Rock MJ, Splaingard ML, Farrell PM. 2005. Preventing early, prolonged vitamin E deficiency: an opportunity for better cognitive outcomes via early diagnosis through neonatal screening.  J Pediatr. Vol. 147, no. 3 suppl. (September): S51-S56.
• Corech R, Rao A, Laxova A, Moss J, Rock MJ, Li Z, Kosorok MR, Splaingard ML, Farrell PM, Barbieri JT. 2005. Early immune response to the components of the type III system of Pseudomonas aeruginosa in children with cystic fibrosis.  J Clin Microbiol. Vol. 43, no. 8. (August): 3956-3962.
• Li Z, Kosorok MR, Farrell PM, Laxova A, West SE, Green CG, Collins J, Rock MJ, Splaingard ML. 2005. Longitudinal developmental of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis.  JAMA. Vol. 293, no. 5. (February): 581-588.
• Li Z, Lai HJ, Kosorok MR, Laxova A, Rock MJ, Splaingard ML, Farrell PM. 2004. Longitudinal pulmonary status of cystic fibrosis children with meconium ileus.  Pediatr Pulmonol. Vol. 38, no. 4. (October): 277-284.
• Koscik RL, Farrell PM, Kosorok MR, Zaremba KM, Laxova A, Lai HC, Douglas JA, Rock MJ, Splaingard ML. 2004. Cognitive function of children with cystic fibrosis: deleterious effect of early malnutrition.  Pediatrics. Vol. 113, no. 6. (June): 1549-1558.
• Bandla H, Splaingard M. 2004. Sleep problems in children with common medical disorders.  Pediatr Clin North Am. Vol. 51, no. 1. (February): 203-227 viii Review.
• Farrell PM, Li Z, Kosorok MR, Laxova A, Green CG, Collins J, Lai HC, Rock MJ, Splaingard ML. 2003. Bronchopulmonary disease in children with cystic fibrosis after early or delayed diagnosis.  Am J Respir Crit Care Med. Vol. 168, no. 9. (November): 1100-1108 Epub 2003 Aug 13.
• Farrell PM, Li Z, Kosorok MR, Laxova A, Green CG, Collins J, Lai HC, Makholm LM, Rock MJ, Splaingard ML. 2003. Longitudinal evalation of bronchopulmonary disease in children with cystic fibrosis.  Pediatr Pulmonary. Vol. 36, no. 3. (September): 230-240.
• Aktay AN, Splaingard ML, Miller T, Freeman ME, Hoeppner H, Werlin SL. 2002. Electrogastrography in children with cystic fibrosis.  Dig Dis Sci. Vol. 47, no. 4. (April): 699-703.
• Banwart B, Splaingard ML, Farrell PM, Rock MJ, Havens PL, Moss J, Ehrmantraut ME, Frank DW, Barbieri JT. 2002. Children with cystic fibrosis produce an immune response against exoenzyme S, a type III cytotoxin of Pseudomonas aeruginosa.  J Infect Dis. Vol. 185, no. 2. (January): 269-270.
• Kosorok MR, Zeng L, West SE, Rock MJ, Splaingard ML, Laxova A, Green CG, Collins J, Farrell PM. 2001. Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition.  Pediatr Pulmonol. Vol. 32, no. 4. (October): 277-287.
• Farrell PM, Kosorok MR, Rock MJ, Laxova A, Zeng L, Lai HC, Hoffman G, Laessig RH, Splaingard ML. 2001. Early diagnosis of cystic fibrosis through neonatal screening prevents severe malnutrition and improves long-term growth, Wisconsin Cystic Fibrosis Neonatal Screening Study Group.  Pediatrics. Vol. 107, no. 1. (January): 1-13.
• Kosorok MR, Jalaluddin M, Farrell PM, Shen G, Colby CE, Laxova A, Rock MJ, Splaingard M. 1998. Comprehensive analysis of risk factors for acqusition of Pseudomonas aeruginosa in young children with cystic fibrosis.  Pediatr Pulmonol. Vol. 26, no. 2. (August): 81-88.
• Rusakow LS, Splaingard ML. 1998. What's CIPRO?.  Pediatrics. Vol. 101, no. 6. (June): e1096.
• Farrell PM, Shen G, Splaingard M, Colby CE, Laxova A, Kosorok MR, Rock MJ, Mischler EH. 1997. Acquistion of Pseudomonas aeruginosa in children with cystic fibrosis.  Pediatrics. Vol. 100, no. 5. (November): eE2.
• Farrell PM, Kosorok MR, Laxova A, Shen G, Koscik RE, Bruns WT, Splaingard M, Mischler EH. 1997. Nutritional benefits of neonatal screening for cystic fibrosis. Wisconsin Cystic Fibrosis Neonatal Screening Study Group.  N Engl J Med. Vol. 337, no. 14. (October): 963-969.
• Thakker JC, Splaingard M, Zhu J, Babel K, Bresnahan J, Havens PL. 1997. Survival and functional outcome of children requiring endotracheal intubation during therapy for severe traumatic brain injury.  Crit Care Med. Vol. 1396, no. 825. (August): e1401.
• Gregg, RG, Simantel A, Farrell PM, Koscik R, Kosorok MR, Laxova A, Laessig R, Hoffman G, Hassemer D, Mischler EH, Splaingard M. 1997. Newborn screening for cystic fibrosis in Wisconsin: comparison of biochemical and molecular methods.  Pediatrics. Vol. 99, no. 6. (June): 819-824.
• Spack L, Gedeit R, Splaingard M, Havens PL. 1997. Failure of agressive therapy to alter outcome in pediatric near-drowning.  Pediatr Emerg Care. Vol. 13, no. 2. (April): 98-102.
• Chusid MJ, Splaingard ML, Tweddell JS, Rice TR, Adams M, Havens PL, Kehl KS. 1996. Pulmonary tuberculosis after lung-liver transplantation from cystic fibrosis.  Pediatr Infect Dis J. Vol. 15, no. 5. (May): 462-464.
• Bousamra M 2nd, Tweddell JS, Wells RG, Splaingard ML, Sty JR. 1996. Wire stent for tracheomalacia in a five-year old girl.  Ann Thorac Surg. Vol. 61, no. 4. (April): 1239-1240 Review.
• Madagame ET, Havens PL, Bresnahan JM, Babel KL, Splaingard ML. 1995. Survival and functional outcome of children requiring mechanical ventilation during therapy for acute bacterial meningitis.  Crit Care Med. Vol. 23, no. 7. (July): 1279-1283.
• Rusakow LS, Guarin M, Lyon RM, Splaingard ML. 1995. Syringomyelia and chiari malformation presenting as scoliosis in cystic fibrosis.  Pediatr Pulmonol. Vol. 19, no. 5. (May): 317-318 Review.
• Gershan WM, Rusakow LS, Chetty A, Splaingard ML. 1994. Resolution of chronic atelectasis in a child with asthma after aerosolized recombinant human DNase.  Pediatr Pulmonol. Vol. 18, no. 4. (October): 268-269.
• Gershan WM, Rusakow LS, Henrickson KJ, Splaingard ML. 1994. Brain abscess caused by Blastomyces dermatitidis in a child with cystic fibrosis.  Chest. Vol. 106, no. 2. (August): 601-603 Review.
• Urban M, Splaingard M, Werlin SL. 1994. Pancreatitis associated with remote traumatic brain injury in children.  Childs Nerv Syst. Vol. 10, no. 6. (August): 388-391.
• Murali PS, Pathial K, Saff RH, Splaingard ML, Atluru D, Kurup VP, Fink JN. 1994. Immune responses to Aspergillus fumigatus and Pseudomonas aeruginosa antigens in cystic fibrosis and allergic bronchopulmonary aspergillosis.  Chest. Vol. 106, no. 2. (August): 513-519.
• Tang TT, Segura AD, Chen YT, Ricci LM, Franciosi RA, Splaingard ML, Lubinsky MS. 1994. Neonatal hypotonia and cardiomyopathy secondary to type IV glycogenosis.  Acta Neuropathol. Vol. 87, no. 5. (January): 531-536.
• McGrath SJ, Splaingard ML, Alba HM, Kaufman BH, Glicklick M. 1992. Survival and functional outcome of children with severe cerebral palsy following gastrostomy.  Arch Phys Med Rehabil. Vol. 73, no. 2. (February): 133-137.
• Konkol RJ, D'DCruz O, Splaingard M. 1991. Central respiratory dysfunction in Mobius syndrome.  J Child Neurol. Vol. 6, no. 3. (July): 278-279.
• Splaingard ML. 1991. Acress of diamonds. Noninvasive ventilatory support.  Chest. Vol. 99, no. 6. (June): 1324-1325.
• Brandstetter Y, Weinhouse E, Splaingard ML, Tang TT. 1990. Cor pulmonale as a complication of methylmalonic acidemia and homocystinuria (Cbl-C type).  Am J Med Genet. Vol. 36, no. 2. (June): 167-171.
• Clydescale TT, Fahs IJ, Kilgore KM, Splaingard ML. 1990. Social dimensions to functional gain in pediatric patients.  Arch Phys Med Rehabil. Vol. 71, no. 7. (June): 469-472.
• Splaingard JL, Gaebler D, Havens P, Kalichman M. 1989. Brain injury: functional outcome in children with tracheostomies and gastrostomies.  Arch Phys Med Rehabil. Vol. 70, no. 4. (April): 318-321.
• Splaingard ML, Hutchins B, Sulton LD, Chaudhuri G. 1988. Aspiration in rehabilitation patients: videofluoroscopy vs bedside clinicial assessment.  Arch Phys Med Rehalabil. Vol. 69, no. 8. (August): 637-640.
• Havens PL, Splaingard ML, Bousounis D, Hoffman GM. 1988. Survival after chloroquine ingestion in a child.  J Toxicol Clin Toxicol. Vol. 26, no. 506. (January): 381-388.
• Pokorny WJ, Black CT, McGill CW, Splaingard ML, Harrison GM, Harberg FJ. 1987. Central venous catheters in older children.  Am Surg. Vol. 53, no. 9. (September): 524-527.
• Splaingard M. 1987. Conversion reaction mimicking quadriparesis in children.  South Med J. Vol. 80, no. 6. (June): 794-795.
• Gaebler,D; Splaingard,M. 1986. SURVIVAL AND OUTCOME IN CHILDREN WITH BRAIN INJURY REQUIRING TRACHEOSTOMY AND GASTROSTOMY.  ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION. Vol. 67, no. 9. (September): 624-624.
• Splaingard M, Splaingard D. 1986. Home care of the ventilator-dependent child: realities and limitations.  Pride Inst J Long Term Home Health Care. Vol. Spring:5, no. 2. (January): 15-20.
• Splaingard ML, Frates RC Jr, Jefferson LS, Rosen CL, Harrison GM. 1985. Home negative pressure ventilation: report of 20 years of experience in patients with neuromuscular disease.  Arch Phys Med Rehabil. Vol. 66, no. 4. (April): 239-242.
• Frates RC Jr, Harrison GM, Splaingard ML. 1984. Home care for children on respirators.  N Engl J Med. Vol. 310, no. 17. (April): 1126-1127.
• Splaingard ML, Frates RC, Jr Harrison GM, Carter RE, Jefferson LS. 1983. Home positive-pressure ventilation. Twenty years' experience.  Chest. Vol. 84, no. 4. (October): 376-382.
• Splaingard ML, Frazier OH, Jefferson LS, Stein F, Harrison GM. 1983. Extracorporeal membrane oxygenation: its role in the survival of a child with adenoviral pneumonia and myocarditis.  South Med J. Vol. 76, no. 9. (September): 1171-1173.
• Lindstrom DR, Conley SF, Splaingard M, Gershan WM. Ibuprofen Therapy and Nasal Polyposis in Cystic Fibrosis Patients. Journal of Otolaryngology 36(5): 309-314, 2007.
• Lofthouse N, Fristad M, Splaingard M, Kelleher K. Parent and child reports of sleep problems associated with early-onset bipolar spectrum disorders. Journal of Family Psychology 21(1): 114-123, 2007.
• Splaingard M, Hayes JR, Smith GA. Impairment of Reaction Time among Children Awakened during Stage 4 Sleep. Sleep 30(1): 104-108, 2007.

• Listed, Best Doctor's in America