Mark A. Ranalli, MD

Mark A. Ranalli, MD, is an attending physician in the Division of Hematology/Oncology/BMT at Nationwide Children’s Hospital and an Associate Professor of Clinical Pediatrics at The Ohio State University College of Medicine. Dr. Ranalli serves as medical director of the Comprehensive Hemoglobinopathy Center at Children’s and oversees the Embryonal Tumor Program. His clinical and academic interests include: cardiopulmonary and cerebrovascular complications in sickle cell anemia; the treatment of neuroblastoma, primary renal tumors, and germ cell malignancies; and the use of novel therapies for >refractory malignancies. Dr. Ranalli is a member of The Ohio State University Comprehensive Cancer Center Institutional Review Board. He serves as the institutional principle investigator for national clinical trials investigating the natural history of iron overload and the management of silent cerebral infarcts in children and young adults with sickle cell anemia.

Gender:

• Male

Languages Spoken:

• English

Research Funding*:

• Silent Infarct Transfusion Trial (SIT Study), Washington University/National Institutes of Health
• Comprehensive Sickle Cell Treatment Center, Ohio Department of Health

Medical School

• University of Chicago Pritzker School of Medicine
  Date Completed: 06/15/1989

Internship

• Children's Hospital of Philadelphia
  Date Completed: 06/30/1990

Residency

• Children's Hospital of Philadelphia
  Date Completed: 06/30/1992

Fellowship

• Children's Memorial Hospital (Chicago)
  Date Completed: 06/30/1999

Department:

• Pediatrics

Section:

• Hematology/Oncology

Speciality:

• Pediatric Hematology Oncology
  
• Pediatrics
  

Date of Appointment at Nationwide Children’s Hospital:

• 11/16/1999

• Bechtel Michael, Ranalli, Mark, Mchugh Kirk, Hains David, Onimoe Grace, Schwaderer Andrew. 2011. Hepatoblastoma and Prune Belly Syndrome: A Potential Association.  Pediatric Nephrology.
• Pai Vinita, Porter Kyle, Ranalli Mark. 2011. Octreotide acetate is efficacious and safe in children for treating diarrhea due to chemotherapy but not acute graft versus host disease.  Pediatric Blood and Cancer. Vol. 56, no. 1. (January): 45-49.
• Lagmay JP, London WB, Gross TG, Termuhlen A, Sullivan N, Axel A, Mundy B, Ranalli M, Canner J, McGrady P, Hall B. 2009. Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor).  Clin Cancer Res.. Vol. 15, no. 16. (August): 5234-5239.
• Lagmay JP, Ranalli M, Arcila M, Baker P. 2009. Clear cell sarcoma of the stomach in a Child: A Rare Diagnosis.  Pediatr Blood Cancer. Vol. 53, no. 2. (August): 214-216.
• Joanne Lagmay, MD; Amanda Termuhlen, MD; Bonita Fung, MD; Mark Ranalli, MD. 2009. Primary Testicular Presentation of Anaplastic Large Cell Lymphoma in a Pediatric Patient.  Journal of Pediatric Hematology/ Oncology. Vol. 31, no. 5. (May): 330-332.
• Lemanek KL, Ranalli M, Lukens C. 2009. A Randomized Controlled Trial of Massage Therapy in Children with Sickle Cell Disease.  Journal of Pediatric Psychology. Vol. 10, no. March: e1093.
• Lemanek K., Ranalli M. 2009. Diseases of the Blood: Sickle Cell Disease.  Handbook of Pediatric Psychology.
• Kerlin BA, Palumbo JS, Nicol KK, Bove KE, Ranalli MA. 2009. Tissue Factor Expression by Common Pediatric Malignant Tumors: A Pilot Feasibility Study.  Haemophilia. Vol. 627, no. 15. (January).
• Diab M, Bechtel M, Coloe J, Kurtz E, Ranalli M. 2008. Treatment of refractory pemphigus erythematosus with rituximab.  Int J Dermatol. Vol. 47, no. 12. (December): 1317-1318.
• Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP; Multi-Center Iron Overload Study Group. 2008. Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia.  Bone. Vol. 43, no. 1. (January): 162-168.
• James T. Naprawa, Deborah Goodman, Bema K. Bonsu, Mark A. Ranalli. 2005. Serum Biomarkers for Identifying Acute Chest Syndrome Among Patients who have Sickle Cell Disease and Present to the Emergency Department.  Pediatrics. Vol. 116, no. 3. (September): 420-425.
• Kapil Saxena MD, MS, Mark Ranalli MD, Nadeem Khan MD, Carol Blanchong MD, Samir Kahwash MD. 2005. Fatal Stroke in a Child with Severe Iron Deficiency Anemia and Multiple Hereditary Risk Factors for Thrombosis.  Clinical Pediatrics. Vol. 44, no. 2. (March): 175-180.
• Lawrence J. Druhan, Jing Ai, Pam Massullo, Tamila Kindwall-Keller, Mark A. Ranalli, and Belinda R. Avalos. 2005. Novel mechanism of G-CSF refractoriness in patients with severe congenital neutropenia.  Blood. Vol. 105, no. 2. (January): 584-591.
• Jacobsohn, DA; Hewlett, B; Ranalli, M; Seshadri, R; Duerst, R; Kletzel, M. 2004. Outcomes of Unrelated Cord Blood Transplants and Allogeneic-Related Hematopoietic Stem Cell Transplants in Children with High-Risk Acute Lymphocytic Leukemia.  Bone Marrow Transplantation. Vol. 34, no. 10. (November): 901-907.
• Koranyi K., Ranalli M. 2003. Mycobacterium Aurum Bacteremia in an immunocompromised Child.  The Pediatric Infectious Disease Journal. Vol. 22, no. 12. (December).
• Wynn, Tung, Heerema Nyla K, Hammond Sue, Ranalli M, Kahwash, Samir. 2003. Acute Lymphoblastic Leukemia with Hypereosinophilia. Report of a Case with 5q Deletion and Review of the Literature.  Pediatric and Developmental Pathology.
• Lemanek K., Ranalli M., Green K., Biega C., Lupia C. 2003. Diseases of the Blood: Sickle Cell Disease and Hemophilia.  Handbook of Pediatric Psychology. Vol. 3rd Edition, no. January.
• Susan E. Crawford, Veronica Stellmach, Mark Ranalli, Xuemei Huang, Olga Volpert, George DeVries, Noël Bouck. 2001. Pigment Epithelium-Derived Factor (PEDF) in Neuroblastoma: A Multifunctional Mediator of Schwann Cell Anti-Tumor Activity.  J Cell Sci. Vol. 114, no. pt 24. (December): 4421-4428.
• Crawford SE, Flores-Stadler EM, Huang L, Tan X, Ranalli MA, Mu Y, Gonzalez-Crussi F. 1998. Rapid Growth of Cutaneous Metastases After Surgical Resection of Thrombospondin Secreting Small Round Blue Cell Tumor of Childhoodg Small Round Blue Cell Tumor of Childhood.  Human Pathology. Vol. 29, no. 10. (October): 1039-1044.