Lynette K. Rogers, PhD :: Nationwide Children's Hospital, Columbus, Ohio

Lynette K. Rogers, Ph.D.

Lynette K. Rogers, Ph.D.

Center for Perinatal Research
Principal Investigator

Neonatology
Principal Investigator

Neonatology Fellowship
Faculty

Contact Information

The Research Institute at Nationwide Children's Hospital
700 Children's Drive
Columbus, Ohio 43205 [ map ]
PH: (614) 355.3456
E-mail Me

Biography

Lynette K. Rogers, Ph.D. is a Principal Investigator in the Center for Perinatal Research at The Research Institute at Nationwide Children’s Hospital. She is an Assistant Professor at The Ohio State University College of Medicine. Dr. Rogers NIH-funded research focuses on lung injury and growth deficits in preterm infants. Specifically, she is interested in natural product therapies that would lessen the long-term morbidities associated with prematurity.

Gender:

  • Female

Languages Spoken:

  • English

Research Interests

Research Center:

Areas of Interest:

  • The ultimate goal of my lab is to identify the causes of premature birth, help design treatments that would prevent prematurity, and strive to help develop efficacious treatments that would decrease morbidities in prematurely born infants. The research efforts in my lab are two fold. First, we are working to identify biomarkers early in the life of a premature infant that would predict outcomes and development of diseases and better understand the mechanisms involved in these disease processes. We use a broad scope of analytical techniques to identify alterations in proteins and lipids in both animal models of premature birth as well as human studies. Secondly, our animal models focus on inflammation resolution. Inflammation is a large component of diseases associated with prematurity, specifically those that involve the lung. Impaired inflammatory resolution may, in part, be responsible for the progression and chronic state of lung diseases in the premature infant. We are working to develop interventions that would improve inflammatory resolution in a newborn mouse model.

Education and Training

Undergraduate

  • University of Southwestern Louisiana
    Date Completed: 06/30/1977

Post Doctoral

  • The Ohio State University
    Date Completed: 06/30/2004

Professional Experience

2005–present

  • Assistant Professor, Department of Pediatrics, Ohio State University, Columbus, Ohio

2005–present

  • Principal Investigator, Columbus Children’s Research Institute, Columbus, Ohio

2004–2005

  • Senior Research Scientist, Columbus Children’s Research Institute, Columbus, Ohio

2000–2004

  • Sr. Research Associate, Columbus Children’s Research Institute, Columbus, Ohio

1991–2000

  • Research Assistant, Department of Pediatrics, Baylor College of Medicine, Houston Texas

1990–1991

  • Research Technician, Shell Oil Co., Houston, Texas

1986–1990

  • Research Technician, Department of Medicine, Baylor College of Medicine, Houston, Texas

1985–1986

  • Research Technician, Exxon Research and Development Co., Baytown, Texas

1977–1978

  • Research Technician, University of Texas Health Science Center, Houston, Texas

Publications

  • Rogers LK and Velten M. 2011. Maternal Inflammation, Growth Retardation, and Preterm Birth: Insights into Adult Cardiovascular Diseases.  Life Sciences. Vol. 89, no. 13-14. (September): 417-421. (IF: 2.6)
  • Velten M, Hutchinson KR, Wold LE, Lucchesi PA, Rogers LK. 2011. Systemic Maternal Inflammation and Neonatal Hyperoxic Induce Remodeling and Impair Left Ventricular Function.  PLoS One. Vol. 6, no. 9. (September): e24544. (IF: 4.6)
  • Rogers LK and Velten M. 2011. Maternal Inflammation, Growth Retardation, and Preterm Birth: Insights into Adult Cardiovascular Diseases. Review of The effects of prematurity on cardiovascular disease.. Life Sciences. Vol. 89, no. 13-14. (September): 417-421. (2.600) [Peer Reviewed] (Published)
  • Cua CL, Rogers LK, Chicoine LG, Augustine M, Jin Y, Nash PL and Nelin LD. 2011. Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.  European Journal of Pediatrics. Vol. 170, no. 7. (July): 859-863. (IF: 1.634)
  • Heyob KM, Rogers LK, Tipple TE, and Welty, SE. 2011. Riboflavin supplementation does not attenuate hyperoxic lung injury in transgenic spc?mthGR mice.  Experimental Lung Research. Vol. 3, no. 37. (April): 155-161. (IF: 1.177)
  • Rogers LK, Valentine CJ, Pennell M, Velten M, Britt RD, Dingess K, Zhao X, Welty SE, and Tipple TE. 2011. Maternal DHA Supplementation Decreases Lung Inflammation in Hyperoxia-Exposed Newborn Mice.  Journal of Nutrition. Vol. 2, no. 141. (February): 214-222. (IF: 4.091)
  • Velten M, Heyob KM, Britt RD, Tipple TE, Welty SE, Rogers LK. 2011. Perinatal Inflammation Contributes to Adult Pulmonary Fibrosis [Abstract]. Respir and Crit Care Med: A4205. [Peer Reviewed] (Published)
  • Britt RD, Locy ML, Tipple TE, Nelin LD, Rogers LK. 2011. Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Mouse Transformed Clara Cells.  Cell Physiol and Biochem. (Formally Accepted)
  • Khandelwal, AR, Hebert, VY, Kleinedler, JJ, Rogers, LK, Ullevig, SL, Asmis, R, Dugas, TR. 2011. Resveratrol and quercetin interact to inhibit neointimal hyperplasia.  Journal of Nutrition. (IF: 4.4) (Formally Accepted)
  • Velten M, Hutchinson KR, Gorr MW, Velten C, Wold LE, Lucchesi P, Rogers LK. 2011. Perinatal Inflammation Causes Adult Cardiac Diseases: A Novel Model for Fetal Origins of Adult Diseases [Abstract]. Experimental Biology: 644.21. [Peer Reviewed] (Published)
  • Valentine CJ, Morrow G, Hodge AE, Augustine M, Pennell M, Haban-Bartz A, Collins K, Rogers LK. 2011. Randomized Controlled Trial of Docosahexaenoic Acid in Women to Improve Donor Milk [Abstract]. Experimental Biology: 590.1. (Published)
  • Kleinedler, JJ, Orchard, E, Foley, JD, Rogers, LK, Hebert, VY, Dugas, TR. 2011. A dietary approach to increase in-stent stenosis in a rat model of stenting angioplasty.  Atherosclerosis. (IF: 4.1) (Formally Accepted)
  • Rogers LK, Dingess KA, Velten M, Heyob K, Valentine CJ. 2011. Maternal DHA Supplementation Attenuates Newborn Hyperoxia-Induced Lung Developmental Deficits into Early Adulthood [Abstract]. Experimental Biology: 990.17. [Peer Reviewed] (Published)
  • Britt RD, Velten M, Nelin LD, Rogers LK. 2011. Aspirin Therapy Enhances Lung Alveolarization in Newborn Pups Exposed to Neonatal Hyperoxia [Abstract]. Experimental Biology: 660.4. [Peer Reviewed] (Published)
  • Valentine CJ, Hodge AE, Dingess KA, Heyob KM, Rogers LK. 2011. Mammary Gland Development is Altered by LPS-Induced Maternal Inflammation [Abstract]. Experimental Biology: 104.8. [Peer Reviewed] (Published)
  • Tipple TE, Rogers LK, Liu Y, Nelin LD, Welty SE. 2011. Thioredoxin Interacting Protein Overexpression Decreases Hypoxia Response Element Promoter Activity in Murine Alveolar Epithelial Cells [Abstract]. Respir and Crit Care Med: A4155. [Peer Reviewed] (Published)
  • Rogers LK, Dingess K, Velten M, Tipple TE. 2011. Maternal DHA Supplementation Attenuates Hyperoxia-Induced Lung Developmental Deficits in Adult Mice [Abstract]. The Toxicologist. Vol. 120: 2193. (Published)
  • Valentine CJ, Morrow G, Fernandez S, Gulati P, Bartholomew D, Long D, Welty SE, Morrow AL, Rogers LK. 2010. Docosahexaenoic Acid and Amino Acid Contents in Pasteurized Donor Milk are Low for Preterm Infants.  Journal of Pediatrics. Vol. 6, no. 157. (December): 906-910. (IF: 4.092)
  • Farrell MR, Rogers LK, Liu Y, Welty SE, and Tipple TE. 2010. Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activity.  Free Radical Biology and Medicine. Vol. 9, no. 49. (November): 1361-1367. (IF: 5.791)
  • Jiang B, Khandelwal A R, Rogers L K, Shi W, Orr A W, and Dugas T R. 2010. Antiretrovirals Induce Endothelial Dysfunction via Oxidant-Dependent Pathways and Promote Neointimal Hyperplasia in C57BL/6 mice.  Toxicological Sciences. Vol. 2, no. 117. (October): 524-536. (IF: 4.814)
  • Stenger MR, Rose MJ, Joshi MS, Rogers LK, Chicoine LG, Bauer JA, Nelin LD. 2010. Inhaled Nitric Oxide Prevents 3-Nitrotyrosine Formation in the Lungs of Neonatal Mice Exposed to >95% Oxygen.  Lung. Vol. 3, no. 188. (March 17): 214-227. (IF: 1.583)
  • Velten M, Heyob K M, Rogers L K, Welty S E. 2010. Deficits in Lung Alveolarization and Function After Systemic Maternal Inflammation and Neonatal Hyperoxia Exposure.  J Appl Physiol. Vol. 5, no. 108. (March 11): 1347-1356. (IF: 3.6)
  • Rogers LK; Tipple TE; Britt RD; Welty SE. 2010. Hyperoxia exposure alters hepatic eicosanoid metabolism in newborn mice.  Pediatric Research. Vol. 67, no. 2. (February 1): 144. (IF: 2.607)
  • Rogers LK, Tipple TE, Heyob KM, Velten M. 2010. Maternal Inflammation and Neonatal Hyperoxia Results in Adult Pulmonary Fibrosis [Abstract]. Free Rad Biol and Med. Vol. 49: S50. [Peer Reviewed] (Published)
  • Nuthakki S, Giannone PJ, Rogers LK, Nelin LD. 2010. Lipopolysaccharide Induced Arginase Activity Limits Inducible Nitric Oxide Synthase Derived NO Production in Rat Intestinal Epithelial Cells [Abstract]. Pediatr Acad Soc, EPAS. Vol. 4421: 512. [Peer Reviewed] (Published)
  • Raffay TM, Locy ML, Hill CL, Rogers LK, Welty SE, Tipple TE. 2010. Hyperoxia Exposure Transiently Increases Clara Cell Secretory Protein Expression in the Lungs of Newborn Mice [Abstract]. Pediatr Acad Soc, EPAS. Vol. 1467: 154. [Peer Reviewed] (Published)
  • Luchsinger J, Rogers LK, Locy ML, Hill CL, Velten, M, Nelin LD, Tipple TE. 2010. Glutathione Reductase Deficiency Alters Lung Development in Newborn Mice [Abstract]. Free Rad Biol and Med. Vol. 49: S51. [Peer Reviewed] (Published)
  • Velten M, Hutchison KR, Lucchesi PA, Rogers LK. 2010. Persistent Ventricular Dysfunction in Mice Exposed to Systemic Maternal Inflammation and Neonatal Hyperoxia [Abstract]. Respir and Crit Care Med. Vol. A1856 [Peer Reviewed] (Published)
  • Velten M, Heyob KM, Rogers LK, Welty SE. 2010. Systemic Maternal Inflammation and Neonatal Hyperoxia Induces a Persistent BPD-Like Phenotype [Abstract]. Pediatr Acad Soc, EPAS. Vol. 4405: 278. [Peer Reviewed] (Published)
  • Velten M, Hutchinson KR, Welty SE, Lucchesi PA, Rogers LK. 2010. Impaired Cardiac Function in Mice Exposed to Systemic Maternal Inflammation and Neonatal Hyperoxia [Abstract]. Pediatr Acad Soc, EPAS. Vol. 3704: 61. [Peer Reviewed] (Published)
  • Britt RD, Welty SE, Nelin SD, Rogers LK. 2010. Low Dose Aspirin Enhances Lung Alveolarization and Decreases Inflammation in Newborn Pups Exposed to Hyperoxia [Abstract]. Pediatr Acad Soc, EPAS. Vol. 4630: 2. [Peer Reviewed] (Published)
  • Valentine CJ, Morrow G, Haban-Bartz A, Collins K, Hodge A, Pennell M, Welty S, and Rogers LK. 2010. Dietary DHA in Midwestern donor milk population is low [Abstract]. Experimental Biology [Peer Reviewed] (Published)
  • Locy ML, Hill CL, Rogers LK, Welty SE, Tipple TE. 2010. Exposure to Hyperoxia Increases Cytoplasmic Phospholipase-A2 Activity in the Lungs of Newborn Mice [Abstract]. Pediatr Acad Soc, EPAS. Vol. 1464: 119. [Peer Reviewed] (Published)
  • Velten M, Britt RD, Heyob KM Rogers LK. 2010. Systemic Maternal Inflammation and Neonatal Hyperoxia Induces Persistent Alterations in Pulmonary Structure and Function [Abstract]. Respir and Crit Care Med: A3897. (Published)
  • Valentine C J, Morrow G, Fernandez S, Gulati P, Bartholomew D, Long D, Welty S E, Morrow A L, and Rogers L K. 2010. Docosahexaenoic Acid and Amino Acid Contents in Pasteurized Donor Milk are Low for the Preterm Infant.  J Pediatrics. (Revised submission)
  • Hill CL, Locy ML, Rogers LK, Welty SE, Tipple TE. 2010. Thioredoxin Interacting Protein and Vascular Endothelial Growth Factor Expression Are Inversely Correlated In Utero and Postnatally [Abstract]. Pediatr Acad Soc, EPAS. Vol. 1467: 150. [Peer Reviewed] (Published)
  • Tipple TE, Farrell MR, Hill CL, Rogers LK, Liu Y, Welty SE. 2010. Thioredoxin-Independent Decreases in Hypoxia Response Element Promoter Activity by Thioredoxin Interacting Protein in Murine Alveolar Epithelial Cell [Abstract]. Pediatr Acad Soc, EPAS. Vol. 1467: 161. [Peer Reviewed] (Published)
  • Kleinedler J J, Orchard E A, Foley J D, Rogers L K and Dugas T R. 2010. A dietary approach to increase in-stent stenosis in a rat model of stenting angioplasty.  Atherosclerosis. (Revised submission)
  • Britt RD, Welty SE, Nelin SD, Rogers LK. 2010. Low Dose Aspirin Administration Improves Lung Development in Newborn Pups Exposed to Hyperoxia [Abstract]. Respir and Crit Care Med: A5749. (Published)
  • Tipple TE; Welty SE; Nelin LD; Hansen JM; Rogers LK. 2009. Alterations of the thioredoxin system by hyperoxia: implications for alveolar development.  American Journal Of Respiratory Cell And Molecular Biology. Vol. 41, no. 5. (November 1): 612. (IF: 4.3)
  • Valentine CJ; Fernandez S; Rogers LK; Gulati P; Hayes J; Lore P; Puthoff T; Dumm M; Jones A; Collins K; Curtiss J; Hutson K; Clark K; Welty SE. 2009. Early amino-acid administration improves preterm infant weight.  Journal Of Perinatology: Official Journal Of The California Perinatal Association. Vol. 29, no. 6. (June 1): 428. (IF: 1.6)
  • Rogers LK; Tipple TE; Nelin LD; Welty SE. 2009. Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen.  Pediatric Research. Vol. 65, no. 1. (January 1): 33. (IF: 2.7)
  • Nuthakki S, Giannone PJ, Rogers LK, Nelin LD. 2009. Lipopolysaccharide Increases Production of Both Nitric Oxide and Urea in Fetal Intestinal Cells [Abstract]. Pediatr Acad Soc, EPAS: 2839.375 (Published)
  • Rogers LK, Tipple TE, Nelin LD, Welty SE. 2009. Hyperoxia-Induced Oxidant Stress in the Livers of Newborn Mouse Pups [Abstract]. The Toxicologist. no. 108: 240 (Published)
  • Velten M, Heyob KM, Rogers LK, Welty SE. 2009. Prenatal Inflammation and Neonatal Hyperoxia Exposure Leads to Changes in Alveolar Wall Structure. [Abstract]. Pediatr Acad Soc, EPAS. no. 3858: 129. (Published)
  • Lynette K. Rogers, Trent E. Tipple, Xuilan Zhao, and Stephen E. Welty. 2009. Maternal DHA Supplementation Decreases Inflammation and Improves Lung Growth in Hyperoxia-Exposed Newborn Mouse Pups [Abstract]. Free Radical Biology and Medicine. Vol. 47, no. S1: S152. (Published)
  • Rogers LK, Tipple TE, Zhao X, Welty, SE. 2009. Maternal DHA Supplementation Decreases Inflammatory Responses in the Lungs of Newborn Mouse Pups Exposed to Hyperoxia. [Abstract]. Respir and Crit Care Med: A3995 (Published)
  • Britt RD, Nelin LD, Welty SE, Rogers LK. 2009. Administration of Lipoxin Analog Decreases Inflammatory Responses and Enhances Resolution Pathways in H441 Cells Treated with LPS [Abstract]. The Toxicologist. no. 108: 392 (Published)
  • Manaloor NV, Augustine MA, Leonhart KL, Reber KM, Rogers LK. 2009. Plasma ADMA Levels Are Elevated at DOL 1-3 in Preterm Infants That Subsequently Develop Necrotizing Enterocolitis. [Abstract]. Pediatr Acad Soc, EPAS: 2510.8 (Published)
  • Trent E. Tipple, Lynette K. Rogers, Yusen Liu, Leif D. Nelin, and Stephen E. Welty. 2009. Overexpression of Thioredoxin Interacting PRotein Decreases Hypoxia Response Element Promoter Activity in Murine Alveolar Epithelial Cells [Abstract]. Free Rad Biol and Med. Vol. 47, no. S1: S103. (Published)
  • Tipple TE, Welty SE, Rogers LK. 2009. Alteration of Lung Thioredoxin Interacting Protein Expression by Hyperoxia: Implications for Alveolar Development [Abstract]. Respir and Crit Care Med: A2627 (Published)
  • Velten M, Heyob KM, Rogers LK, Welty SE. 2009. Maternal Inflammation Leads to Delayed Pulmonary Development in Mice [Abstract]. Respir and Crit Care Med: A4123 (Published)
  • Rodney D. Britt, Stephen E. Welty, Leif D. Nelin, and Lynette K. Rogers. 2009. Low Dose Aspirin Administration Improves Lung Development in Newborn Pups Exposed to Hyperoxia [Abstract]. Free Radical Biology and Medicine. Vol. 47, no. S1: S98. (Published)
  • Velten M, Heyob KM, Rogers LK, Welty SE. 2009. Combined Effect of Maternal LPS Administration at E16 and Neonatal Hyperoxia-Exposure on Lung Inflammation and Fibrosis. [Abstract]. Respir and Crit Care Med,: A4114 (Published)
  • Heyob KM, Rogers LK, Welty SE. 2009. Transgenic Mice with Glutathione Reductase Targeted to the Mitochondria of Type II Cells Are Not Riboflavin Deficient in Hyperoxia [Abstract]. Respir and Crit Care Med: A5004. (Published)
  • Tipple TE, Rogers LK, Nelin LD, Welty SE. 2009. Thioredoxin Interacting Protein-Dependent Regulation of VEGF Production by Alveolar Epithelial Cells. [Abstract]. Pediatr Acad Soc, EPAS. no. 3859: 145 (Published)
  • Rogers LK, Nelin LD, Welty SE. 2008. Plasma Eicosanoid Levels on Day of Life 1 are Associated with Diagnosis of BPD at 36 weeks [Abstract]. Pediatr Acad Soc, EPAS (Published)
  • Tipple TE, Rogers LK, Nelin LD, Welty SE. 2008. Thioredoxin Interacting Protein-Dependent Regulation of Vascular Endothelial Growth Factor Production by Alveolar Epithelial Cells. [Abstract]. Free Rad Biol and Med. no. 45: S48. (Published)
  • Rogers LK, Tipple TE, Nelin LD, Welty SE. 2008. Oxidant Stress in the Livers of Mouse Pups Exposed to Hyperoxia [Abstract]. Free Rad Biol and Med. no. 45: S74. (Published)
  • Stenger MR, Tipple TE, Rogers LK, Liu Y, Nelin LD. 2008. Inhaled Nitric Oxide Prevents the Hyperoxia-Induced Activation of P38 and JNK in Neonatal Mice Lungs. [Abstract]. Free Rad Biol Med. no. 45: S117. (Published)
  • Rogers LK, Tipple TE, Nelin LD, Welty SE. 2008. Suppression of PPARg activity causes increased proliferation and decreased neutrophil accumulation in the lungs of newborn mice exposed to >95% O2. [Abstract]. The Toxicologist. no. 102: 363. [Peer Reviewed] (Published)
  • Heyob KM, Rogers LK, Welty SE. 2008. Glutathione Reductase Targeted to Type ll Cells Does Not Protect Mice from Hyperoxic Lung Injury.  Am J Resp Mol Cell Biol.. Vol. 39, no. 6. : 683-688. (IF: 4.608)
  • Valentine CJ, Morrow GB, Augustine MD, Welty SE, Rogers LK. 2007. Pasteurized Donor Milk Processing Does Not Alter Fatty Acids and Sterols but Concentrations of Deocosahexaenoic Acid (DHA) Are Low [Abstract]. Pediatr Acad Soc, EPAS. no. 60: 7926.5 (Published)
  • Rogers LK, Nelin LD, Welty SE. 2007. Increases in Lipid Oxidation Products Are Detectable by One Day of Life in Newborn Mice Exposed to Hyperoxia [Abstract]. Respir and Crit Care Med. no. 175: A94 (Published)
  • Tipple TE, Welty SE, Rogers LK, Hansen TN, Choi YE, Kehrer JP, Smith CV. 2007. Thioredoxin-related mechanisms in hyperoxic lung injury in mice.  American Journal of Respiratory Cell and Molecular Biology. Vol. 37, no. 4. : 405-413. (IF: 4.6)
  • Rogers LK, Welty SE, Nelin LD. 2007. Newborn Mice Exposed to Hyperoxia Exhibit Increases in Lipid Oxidation Products and Cytoplasmic Phospholipase A2 [Abstract]. The Toxicologist. Vol. 96: 250 (Published)
  • Rogers LK, Nelin LD, Tipple TE, Welty SE. 2007. Administration of GW9662, a PPARg antagonist, causes decreased inflammation and increased alveolar number in the lungs of newborn mice exposed to>95% O2. [Abstract]. Free Rad Biol and Med. no. 43: S144. (Published)
  • Meng X, Heyob K, Nelin LD, Welty SE, Rogers LK. 2007. Newborn Mice Exposed To Hyperoxia Exhibit Decreases in PPARg Expression [Abstract]. Pediatr Acad Soc, EPAS. Vol. 60: 7935. (Published)
  • Park MS, Rieger-Fackeldey E, Schanbacher BL, Cook AC, Bauer JA, Rogers LK, Hansen TN, Welty SE, Smith CV. 2007. Altered Expressions of Fibroblast Growth Factor Receptors and Alveolarization in Neonatal Mice Exposed to 85% Oxygen.  Pediatric Research. Vol. 6, no. 62. : 652-657. (IF: 2.8)
  • Augustine MS, Meng X, Welty SE, Nelin LD, Rogers LK. 2007. Increases in Lipid Oxidation Products are Detectable at One Day of Life in Newborn Mice Exposed to Hyperoxia [Abstract]. Pediatr Acad Soc EPAS. Vol. 60: 7931 (Published)
  • Tipple TE, Rogers LK, Nelin LD, Welty SE. 2007. Sublethal Hyperoxia Alters Hepatic but Not Pulmonary Thioredoxin-1 Levels in Newborn Mice [Abstract]. Pediatr Acad Soc, EPAS. Vol. 4, no. 60: 8434 (Published)
  • Heyob K, Rogers LK, Welty SE. 2007. Overexpression of Glutathione Reductase in Type-ll Cells Does Not Attenuate Hyperoxia-Induced Lung Injury [Abstract]. Pediatr Acad Soc, EPAS. Vol. 3, no. 60: 8434 (Published)
  • Leonhart KL, Meng X, Welty SE, Nelin LD, Rogers LK. 2007. Plasma Nitrotyrosine Formation is Correlated to Gestational Age in Premature Infants [Abstract]. Pediatr Acad Soc, EPAS. Vol. 19, no. 60: 7935 (Published)
  • Heyob K, Rogers LK, Welty SE. 2007. cPLA2 and sPLA2 Activities Are Not Altered in Hyperoxic Lung Injury in Mice [Abstract]. Pediatr Acad Soc, EPAS. Vol. 2, no. 60: 8434 (Published)
  • Stenger MR, Chicoine LG, Rogers LK, Hatch DM, Welty SE, Nelin LD. 2006. Adding Nitric Oxide to a Hyerpoxic Exposure Results in 3-Nitrotyrosine Formation and Neutrophil Influx in the Lungs of Neonatal Mice [Abstract]. Pediatr Acad Soc, E-PAS. no. 59: 4365.6 (Published)
  • Malleske, Daniel, T; Rogers, Lynette, K; Velluci, Sean, M; Young, Tamara, L; Park, Min, S; Long, Donald, W; Welty, Stephen, E; Smith, Charles, V; Nelin, Leif D. 2006. Hyperoxia increases hepatic arginase expression and ornithine production in mice.  Toxicology and applied pharmacology. Vol. 215, no. 1. : 109-17. (IF: 4.7)
  • Smith CV, Heyob KM, Jenniskens FA, Welty SE, and Rogers LK. 2006. Oxidant responses in LPS-induced preterm birth in mice [Abstract]. The Toxicologist. no. 90: 12351. (Published)
  • Tipple TE, Rogers LK, Welty SE, and Smith CV. 2006. Defense Against Hyperoxic Lung Injury in Glutathione Reductase-Deficient Mice Mediated by Thioredoxin-Dependent Mechanisms [Abstract]. Pediatr Acad Soc, EPAS. no. 59: 4841.158 (Published)
  • Hatch DM, Stenger MR, Young TL, Chicoine LG, Rogers LK, Nelin LD. 2006. Nitric Oxide Preserves Lung Growth and Increases FGF Receptor Signaling in Neonatal Mice Exposed to Hyperoxia [Abstract]. Pediatr Acad Soc, E-PAS. no. 59: 4365.2 (Published)
  • Rogers LK, Leinweber BL, and Smith CV. 2006. Detection of modifications of protein thiols in complex tissue samples [Abstract]. The Toxicologist. no. 90: 123 (Published)
  • Richter JM, Rogers LK, Welty SE, and Smith CV. 2006. Hyperoxia-Induced Increases in Oxysterols and Hydroxy Fatty Acids in Lungs and BAL Fluids of Mice In Vivo [Abstract]. Pediatr Acad Soc, EPAS. no. 59: 5168.11 (Published)
  • Heyob KM, Jiminez-Perez M, Meng XM, Rogers LK, Welty SE, and Smith CV. 2006. Effects of LPS and Diquat on Preterm Birth and Postnatal Development in Strains of Mice Differentially Sensitive to Oxidant Stresses [Abstract]. Pediatr Acad Soc, EPAS. no. 59: 5578.512 (Published)
  • Rogers, Lynette, K; Leinweber, Barbara, L; Smith, Charles V. 2006. Detection of reversible protein thiol modifications in tissues.  Analytical biochemistry. Vol. 358, no. 2. : 171-84. (IF: 2.9)
  • Rogers LK; Bates CM; Welty SE; Smith CV. 2006. Diquat induces renal proximal tubule injury in glutathione reductase-deficient mice.  Toxicology and applied pharmacology. Vol. 217, no. 3. : 289-98. (IF: 4.7)
  • Rogers LK, Leinweber BL, and Smith CV. 2006. Detection and Quantitation of Reversibly Oxidized Protein Thiols in Oxidant Stress Responses In Vivo [Abstract]. Pediatr Acad Soc, EPAS. no. 59: 4812.53 (Published)
  • Rogers LK, Nelin LD, Welty SE. 2006. Newborn Mice Exposed to Hyperoxia Exhibit Increases in Lipid Oxidation Products but Decreases in Levels of 15-Lipoxygenase and PPARg [Abstract]. Free Rad Biol Med. Vol. S1, no. 41: S151. (Published)
  • Tipple TE, Rogers LK, Smith CV, and Welty SE. 2006. Sublethal Hyperoxia Alters Pulmonary and Hepatic Thioredoxin-1 Levels in Neonatal Mice [Abstract]. Free Rad Biol Med. Vol. S1, no. 41: S17 (Published)
  • Nelin LD, Stenger MR, Rogers LK, Welty SE, and Liu Y. 2006. Mitogen Activated Protein Kinase Phosphatase-1 Regulates Nitric Oxide Production in LPS Stimulated Peritoneal Macrophages [Abstract]. Free Rad Biol Med. Vol. S1, no. 41: S52 (Published)
  • Stenger MR, Hatch DM, Rogers LK, Mandar J, Chicoine LG, Bauer JA, Nelin LD. 2006. Nitric Oxide Prevents the Hyperoxia-Induced Arrested Alveolarization and Decreased FGF-10 Levels in Neonatal Mice [Abstract]. Free Rad Biol Med. Vol. S1, no. 41: S54 (Published)
  • Nelin L, Rogers LK, Young T, Malleske D, Welty SE, and Smith CV. 2005. Hyperoxia decreases hepatic nitric oxide production, but increases hepatic orithine production and arginase expression in mice [Abstract]. Free Rad Biol Med. Vol. S1, no. 39: S90 (Published)
  • Tipple TE, Welty SE, Rogers LK, Smith CV, and Hansen TN. 2005. Aurothioglucose-treated glutathione reductase-deficient mice exhibit enhanced sensitivity to hyperoxia suggesting cross-talk between thioredoxin and glutathione systems [Abstract]. Proc Amer Thorac Soc. no. 2: A468 (Published)
  • Rogers LK, Meng X, Augustine MS, Welty SE, Smith CV. 2005. GR-deficient mice (GR1a1Neu) are susceptible to diquat-induced hepatic injury [Abstract]. The Toxicologist. Vol. S1, no. 84: 351 (Published)
  • Tipple TE, Rogers LK, Smith CV, Welty SE, and Hansen TN. 2005. Enhanced sensitivity to hyperoxia after aurothioglucose treatment suggests cross-talk between thioredoxin and glutathione systems in glutathione reductase-deficient mice [Abstract]. Pediatr Acad Soc. no. 57: 813 (Published)
  • Nelin LD, Malleske DT, Velluci SM, Young TL, Rogers LK, Park MS, Welty SE, and Smith CV. 2005. Exposure of mice to hyperoxia increases hepatic arginase [Abstract]. Pediatr Acad Soc. no. 57: 1222 (Published)
  • Rogers LK, Bates CM, Welty SE, and Smith CV. 2005. Diquat administration induces renal proximal tubule injury in glutathione reductase deficient mice [Abstract]. Free Rad Biol Med. Vol. S1, no. 39: S140 (Published)
  • Smith CV, Meng X, Hansen TN, Welty SE, and Rogers LK. 2005. Glutathione reductase-deficient mice demonstrate greater susceptibility to reactive oxygen species-mediated damage in vivo [Abstract]. Pediatr Acad Soc. no. 57: 1784 (Published)
  • Stenger M, Chicoine L, Smith CV, Welty SE, Rogers LK, and Nelin L. 2005. Nitric oxide exposure increases mortality in neonatal mice exposed to hyperoxia. [Abstract]. Free Rad Biol Med. Vol. S1, no. 39: S93 (Published)
  • Tipple TE, Rogers LK, Welty SE, Hansen TN, and Smith CV. 2005. Thioredoxin-dependent mechanisms in defense against hyperoxic lung injury in mice [Abstract]. Free Rad Biol Med. Vol. S1, no. 39: S20 (Published)
  • Stenger MR, Chicoine LG, Smith CV, Rogers LK, Welty SE, and Nelin LD. 2005. Survival and growth of neonatal mice exposed to nitric oxide and hyperoxia [Abstract]. Pediatr Acad Soc. no. 57: 1757 (Published)
  • Welty SE, Rogers LK, Tipple TE, Hansen TN, Smith CV. 2005. Selective enhancement of hyperoxic lung injury by aurothioglucose in glutathione reductase-deficient mice suggests cross-talk between thioredoxin and glutathione systems [Abstract]. The Toxicologist. Vol. S1, no. 84: 379 (Published)
  • Heyob KM, Jenniskens FA, Rogers LK, and Smith CV. 2005. Oxidant stress in LPS-induced preterm birth in mice. [Abstract]. Pediatr Acad Soc, EPAS. no. 57: 808. (Published)
  • Smith CV; Tamura T; Rogers LK; Rogers BJ; Hansen TN; Welty SE. 2004. Genetic mutation analysis of the glutathione reductase hypomorphic mice Gr1a1Neu indicates a genetic knockout animal. [Abstract]. Toxicol Appl Pharmacol. (March) (Published)
  • Rogers LK, Tamura T, Rogers BJ; Hansen TN; Welty SE, and Smith CV. 2004. Molecular mechanisms of subcellular localization of human glutathione reductase [Abstract]. Toxicol Appl Pharmacol. (March) (Published)
  • Welty SE, Park MS, Schanbacher BL, Rogers LK, Cook AC, Hansen TN, Bauer JA, and Smith CV. 2004. Arrested lung development associated with changes in temporal expressions of fibroblast growth factor (FGF) receptors-3 and ?4 in newborn mice exposed to sublethal hyperoxia. [Abstract]. Toxicol Appl Pharmacol. (March) (Published)
  • Meng X, Manson ME, Rogers LK, Shepherd EG, Smith CV, and Liu Y. 2004. Overdose of acetaminophen activates c-Jun N-terminal kinases. [Abstract]. Pediatr Res. no. 55: 586A (Published)
  • Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. 2004. A novel mechanism for nuclear localization of glutathione reductase [Abstract]. Pediatr Res. no. 55: 457A (Published)
  • Park MS, Schanbacher BL, Cook AC, Joshi MS, Rogers LK, Hansen TN, Smith CV, Bauer JA, and Welty SE. 2004. Abnormalities of lung development from exposure of newborn mice to sublethal hyperoxia: Nitration of protein tyrosines and impaired nitric oxide regulation. [Abstract]. Amer J Respir Crit Care Med. no. 169: A422 (Published)
  • Watson DG, Tamura T, Rogers LK, Hansen TN, and Smith CV. 2004. Cytotoxicity of acetaminophen, N-acetyl-p-benzoquinone imine (NAPQI), and diquat in Chinese Hamster Ovary (CHO) cells with genetically modified glutathione reductase activities [Abstract]. Pediatr Res. no. 55: 457A-458A. (Published)
  • Rogers, Lynette, K; Tamura, Toshiya; Rogers, Bryan, J; Welty, Stephen, E; Hansen, Thomas, N; Smith, Charles V. 2004. Analyses of glutathione reductase hypomorphic mice indicate a genetic knockout.  Toxicological sciences. Vol. 82, no. 2. : 367-73. (IF: 3.4)
  • Rieger-Fackeldey EP, Park MS, Schanbacher BL, Cook AC, Joshi MS, Rogers LK, Hansen TN, Smith CV, Bauer JA, and Welty SE. 2004. Abnormalities of lung development from exposure of newborn mice to sublethal hyperoxia: nitration of protein tyrosines and impaired nitric oxide regulation [Abstract]. Pediatr Res. no. 55: 451A (Published)
  • Tipple TE, Rogers LK, Welty SE, Hansen TN, and Smith CV. 2004. Enhanced expression of thioredoxin-2 in mice genetically deficient in glutathione reductase [Abstract]. Free Rad Biol Med. Vol. S1, no. 37: S22 (Published)
  • Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. 2004. Mutation analysis reveals that the Gr1a1Neu (glutathione reductase hypomorph mice) are a genetic knockout. [Abstract]. Pediatr Res. no. 55: 458A (Published)
  • Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. 2004. Nuclear localization of human glutathione reductase requires elements of the mitochondrial targeting signal. [Abstract]. Free Rad Biol Med. Vol. S1, no. 37: S71 (Published)
  • Smith CV, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Rogers LK. 2004. Nuclear glutathione reductase colocalizes with thioredoxin and acetylated histone 3 [Abstract]. Toxicol Appl Pharmacol. no. 197: 335 (Published)
  • Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. 2004. The mitochondrial targeting signal is necessary but not sufficient for nuclear localization of human glutathione reductase [Abstract]. Toxicol Appl Pharmacol. no. 197: 334. (Published)
  • Tipple TE, Choi YE, Rogers LK, Hansen TN, Welty SE, Kehrer JP, and Smith CV. 2004. Enhanced expression of thioredoxin-2 in mice genetically deficient in glutathione reductase [Abstract]. Pediatr Res. no. 55: 457A (Published)
  • Jopperi-Davis, Katrina, S; Park, Min Soo; Rogers, Lynette, K; Backes, Carl H Jr; Lim, In Kyoung; Smith, Charles V. 2004. Compartmental inhibition of hepatic glutathione reductase activities by 1,3-bis(2-chloroethyl)-N-nitrosourea (BCNU) in Sprague-Dawley and Fischer-344 rats.  Toxicology letters. Vol. 147, no. 3. : 219-28. (IF: 2.5)
  • Wright LJ, Meng X, Augustine MS, Rogers LK, and Smith CV. 2004. Protection against hepatotoxic effects of acetaminophen in mice by dimethyl sulfoxide [Abstract]. Pediatr Res. no. 55: 588A (Published)
  • Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. 2004. Subnuclear localization of glutathione reductase [Abstract]. Pediatr Res. no. 55: 457A. (Published)
  • Welty SE, Park MS, Schanbacher BL, Cook AC, Joshi MS, Rogers LK, Hansen TN, Bauer JA, and, Smith CV. 2004. Exposure of newborn mice to sublethal hyperoxia causes abnormalities of lung development from, nitration of protein tyrosines, and impaired nitric oxide regulation [Abstract]. Toxicol Appl Pharmacol. no. 197: 336 (Published)
  • Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. 2004. Nuclear localization of glutathione reductase and subnuclear colocalization with thioredoxin [Abstract]. Free Rad Biol Med. Vol. S1, no. 34: S71 (Published)
  • Rogers LK, Smith CV. 2003. Coenzyme A and coenzyme A-glutathione disulfide measurements by HPLC. In Current Protocols in Toxicology. Vol. 1. Edited by Maines MD. New York City, New York, USA: John Wiley and Sons. 6.9.1-6.9.6.
  • Park MS, Schanbacher BL, Jopperi-Davis KS, Rogers LK, Bauer JA, Hansen TN, Smith CV, and Welty SE. 2003. Effects of 85% oxygen on alveolar development in newborn mice. [Abstract]. Respir Crit Care Med. no. 167: A381 (Published)
  • Malleske DT, Park MS, Rogers LK, Long DW, Smith CV, and Nelin LD. 2003. Hyperoxia decreases liver nitric oxide and increases liver ornithine in mice [Abstract]. Pediatr Res. no. 53: 572A (Published)
  • Rogers LK, Park MS, Hansen TN, Welty SE, and Smith CV. 2003. Effects of genetically diminished glutathione reductase (GR) activities in mice on susceptibilities to hyperoxic lung injury. [Abstract]. Pediatr Res. no. 53: 356A (Published)
  • Park MS, Schanbacher BL, Jopperi-Davis K, Rogers LK, Cook AC, Bauer JA, Hansen TN, Smith CV, and Welty SE. 2003. Developmental expressions of the genes related to alveolarization in newborn mice exposed to 85% O2 [Abstract]. Pediatr Res. no. 53: 439A (Published)
  • Park MS, Rogers LK, Hansen TN, Welty SE, and Smith CV. 2003. Developmental expressions of Clara cell secreted protein (CCSP) and glutathione reductase (GR) in lungs of newborn mice exposed to 85% O2. [Abstract]. Amer J Respir Crit Care Med. no. 167: A386 (Published)
  • Park MS, Rogers LK, Hansen TN, Welty SE, and Smith CV. 2003. Effects of hyperoxia on expressions of glutathione reductase (GR) and Clara cell secreted protein (CCSP) in lungs of mice [Abstract]. Amer J Respir Crit Care Med. no. 167: A594. (Published)
  • Rogers LK, Park MS, Welty SE, Hansen TN, and Smith CV. 2003. Diminished glutathione reductase activities in genetically altered mice (Gr1a1Neu) do not enhance acetaminophen hepatotoxicity. [Abstract]. Pediatr Res. no. 53: 561A (Published)
  • Park MS, Rogers LK, Hansen TN, Welty SE, and Smith CV. 2003. Effects of exposure to > 95% O2 on levels of Clara cell secreted protein (CCSP), glutathione reductase (GR), and glutathione peroxidase (GPX) mRNAs in mouse lungs. [Abstract]. Pediatr Res. no. 53: 576A (Published)
  • Tipple TE, Rogers LK, Hansen TN, Welty SE, and Smith CV. 2003. Enhanced thioredoxin (TRX) levels as possible adaptive responses in mice genetically hypomorphic in glutathione reductase (GR) activities [Abstract]. Pediatr Res. no. 53: 454A (Published)
  • Tamura T, Rogers LK, Welty SE, Hansen TN, and Smith CV. 2003. Nuclear and mitochondrial expression of human glutathione reductase cDNA driven by the human genomic mitochondrial targeting signal. [Abstract]. Pediatr Res. no. 53: 454A (Published)
  • Rogers LK, Smith CV. 2003. Coenzyme A and coenzyme A-glutathione disulfide measurements by HPLC.  Protocols Toxicol. Vol. 6.8: 1-6.
  • Lepp NT, Shepherd EG, Rogers LK, Park MS, Hansen TN, Welty SE, and Smith CV. 2003. Furosemide-induced hepatic necrosis in female mice in vivo. Thiol-disulfide biomarkers of oxidant stress responses. [Abstract]. Pediatr Res. no. 53: 562A (Published)
  • Jopperi-Davis K, Park MS, Rogers LK, Backes CH Jr., and Smith CV. 2003. Compartmental inhibition of glutathione reductase activities by BCNU in Sprague-Dawley (SD) and Fischer-344 (F344 rats). [Abstract]. Pediatr Res. no. 53: 561A (Published)
  • Rogers LK, Park MS, Hansen TN, Welty SE, and Smith CV. 2003. Acetaminophen hepatotoxicity is not enhanced in genetically altered mice (Gr1a1Neu) with diminished glutathione reductase activities. [Abstract]. Toxicologist. no. 72: 350 (Published)
  • Fernandes CJ, Liang R, O'Donovan DJ, Park MS, Rogers LK, Welty SE, Hansen TN, and Smith CV. 2003. . Glutamate-cysteine ligase activities in mice with genetically compromised glutathione reductase expression. [Abstract]. Pediatr Res. no. 53: 409A (Published)
  • Welty SE, Park MS, Rogers LK, Hansen TN, and Smith CV. 2003. Hyperoxic lung injury in glutathione reductase hypomorphic mice. [Abstract]. Amer J Respir Crit Care Med. no. 167: A385 (Published)
  • Giannone PJ, Rogers LK, Welty SE, and Smith CV. 2003. Oxidative modifications of recombinant human Clara cell secretory protein (rhCC10) by myeloperoxidase (MPO) and HOCl in vitro [Abstract]. Pediatr Res. no. 53: 416A (Published)
  • Park MS, Rogers LK, Hansen TN, Welty SE, and Smith CV. 2003. Effects of hyperoxia on lung mRNA levels of Clara cell secreted protein (CCSP) and glutathione reductase (GR) in newborn mice [Abstract]. Pediatr Res. no. 53: 415A. (Published)
  • Welty SE, Park MS, Rogers LK, Hansen TN, and Smith CV. 2003. Divergent effects of hyperoxia on expression of CC10 and glutathione reductase messenger RNA levels in lungs of mice. [Abstract]. Toxicologist. no. 72: 10-11. (Published)
  • Smith CV, Park MS, Rogers LK, Hansen TN, and Welty S. 2003. Hyperoxic lung injury in mice with genetic deficiencies in glutathione reductase activities. [Abstract]. Toxicologist. no. 72: 11 (Published)
  • Shepherd EG, Lepp NT, Rogers LK, Park MS, Hansen TN, Welty SE, and Smith CV. 2003. Furosemide-induced hepatotoxicity in vivo in mice genetically deficient in glutathione reductase [Abstract]. Pediatr Res. no. 53: 561A (Published)
  • Park MS, Backes CH, Jopperi-Davis KS, Rogers LK, and Smith CV. 2002. Sex differences in compartmental expression of glutathione-dependent antioxidants in Fischer-344 rats. [Abstract]. Pediatr Res: 312A (Published)
  • Rogers LK, Welty SE, Hansen TN, and Smith CV. 2002. Glutathione reductase activities are increased in the nuclei of H441 cells during S phase of the cell cycle [Abstract]. Amer J Respir Crit Care Med. no. 165: A53 (Published)
  • O'Donovan, Donough, J; Rogers, Lynette, K; Kelley, Donald, K; Welty, Stephen, E; Ramsay, Patricia, L; Smith, Charles V. 2002. CoASH and CoASSG levels in lungs of hyperoxic rats as potential biomarkers of intramitochondrial oxidant stresses.  Pediatric research. Vol. 51, no. 3. : 346-53. (IF: 3.3)
  • Rogers LK, Hansen TN, Welty SE, and Smith CV. 2002. Cell cycle-dependent increases in nuclear glutathione reductase activities in Chinese Hamster Ovary cells. [Abstract]. Pediatr Res: 312A (Published)
  • Smith CV, Park MS, Rogers LK, Hansen TN, and Welty SE. 2002. Hyperoxic lung injury in mice with genetic deficiencies in glutathione reductase activities [Abstract]. Free Radic Biol Med. no. 33: S358 (Published)
  • Rogers LK, Hansen TN, Welty SE, and Smith CV. 2002. Nuclear glutathione reductase activities are increased during S phase of cell cycle in Chinese hamster ovary (CHO) cells [Abstract]. Toxicol Sci. no. 66: 143 (Published)
  • Welty SE, Jenniskens FA, Jopperi-Davis KS, Walters LC, Rogers LK, and Smith CV. 2002. Effects of fasting on tissue contents of coenzyme A and related intermediates [Abstract]. Toxicol Sci. no. 66: 143-144. (Published)
  • Rogers, Lynette, K; Gupta, Sanjiv; Welty, Stephen, E; Hansen, Thomas, N; Smith, Charles V. 2002. Nuclear and nucleolar glutathione reductase, peroxidase, and transferase activities in livers of male and female Fischer-344 rats.  Toxicological sciences : an official journal of the Society of Toxicology. Vol. 69, no. 1. : 279-85. (IF: 3.3)
  • Jenniskens, Floor, A; Jopperi-Davis, Katrina, S; Walters, Lauren, C; Schorr, Erica, N; Rogers, Lynette, K; Welty, Stephen, E; Smith, Charles V. 2002. Effects of fasting on tissue contents of coenzyme A and related intermediates in rats.  Pediatric research. Vol. 52, no. 3. : 437-42. (IF: 3.3)
  • O'Donovan DJ, Kelley DK, Rogers LK, Welty SE, Ramsay PL, Smith CV. 2002. Mitochondrial oxidant stress iin hyperoxia:CoASH and CoASSG.  Pediatr Res. Vol. 51. : 346-353. (IF: 3.3)
  • Welty SE, Park MS, Rogers LK, Hansen TN, and Smith CV. 2002. Pretranslational effects on expression of CC10 in lungs of mice exposed to hyperoxia. [Abstract]. Free Radic Biol Med. no. 33: S356 (Published)
  • Fernandes, Caraciolo, J; Rong, Liang; Tamura, Toshiya; Stewart, Kerry, D; Rogers, Lynette, K; McMicken, Harilyn, W; Elliston, Jonathan, F; Hansen, Thomas, N; Smith, Charles V. 2002. Stable transfection of Chinese hamster ovary cells with glutamate-cysteine ligase catalytic subunit cDNA confers increased resistance to tert-butyl hydroperoxide toxicity.  Toxicology letters. Vol. 136, no. 2. : 107-20. (IF: 2.2)
  • Smith CV, Jopperi-Davis KS, Schorr EN, Rogers LK, and Welty SE. 2002. Acute effects of diquat on redox status of hepatic coenzyme A and glutathione in Fischer-344 rats [Abstract]. Toxicol Sci. no. 66: 145 (Published)
  • Rogers LK, Hansen TN, Welty SE, and Smith CV. 2002. Cell cycle-dependent increases in glutathione reductase activities in H441 cells [Abstract]. Pediatr Res. no. 52: 352A (Published)
  • Rogers LK, Welty SE, Hansen TN, Tamura T, and Smith CV. 2001. Nuclear glutathione reductase (GR) activities are increased in Chinese hamster ovary (CHO) cells stably transfected with GR containing the MnSOD mitochondrial targeting signal [Abstract]. Pediatr Res. no. 49: 327A (Published)
  • Jenniskens FA, Schorr EN, Rogers LK, Dunaway DJ, Smith CV, and Nowicki PT. 2001. Oxidant stress and endothelin expression in newborn, but not juvenile swine intestine after ischemia-reperfusion [Abstract]. Free Rad Biol Med. no. 31: S94. (Published)
  • Jenniskens FA, Jopperi-Davis KS, Walters LC, Rogers LK, Welty SE, and Smith CV. 2001. Decreases in lung contents of Coenzyme A in hyperoxic rats are not attributable to diminished food intake [Abstract]. Free Rad Biol Med. no. 31: S32. (Published)
  • Rogers LK, Welty SE, Hansen TN, Tamura T, and Smith CV. 2001. Increased glutathione reductase activities in CHO cells do not protect against 7-ketocholesterol toxicity [Abstract]. The Toxicologies. no. 60: 209-210. (Published)
  • Rogers LK, Welty SE, Hansen TN, Tamura T, and Smith CV. 2001. Enhanced glutathione reductase (GR) activities do not attenuate 7-ketocholesterol cytotoxicity [Abstract]. Pediatr Res. no. 49: 327A (Published)
  • Wong YL, Smith CV, McMicken HW, Rogers LK, Welty SE. 2001. Mitochondrial thiol status in the liver is altered by exposure to hyperoxia.  Toxicology letters. Vol. 123, no. 2-3. : 179-93. (IF: 1.6)
  • Welty SE, Rogers LK, Wong YL, and Smith CV. 2001. Hepatic oxidant stress responses in mice exposed to hyperoxia [Abstract]. Toxicol Sci. no. 60: 425 (Published)
  • Welty SE, Wong YL, Rogers LK, and Smith CV. 2001. Intramitochondrial oxidant stress responses in the livers of hyperoxic mice [Abstract]. Pediatr Res. no. 49: 266A (Published)
  • Wong YL, Smith CV, McMicken HW, Rogers LK, and Welty SE. 2001. Hyperoxia diminishes mitochondrial glutathione reductase activities and alters specific mitochondrial protein thiols in murine lung and liver [Abstract]. FASEB J. no. 15: A293 (Published)
  • Smith CV, Rogers LK, Raya JL, Gest AL, and Taylor AA. 2000. Antioxidant and antiatherogenic effects of low dose acetaminophen in hypercholesterolemic rabbits in vivo [Abstract]. Pediatr Res. no. 47: 473A (Published)
  • Hougland KT, Rogers LK, Raya JL, McMicken HW, Smith CV, and Welty SE. 2000. Exposure of lung derived H441 cells to 7-ketocholesterol (7-Keto) leads to cytotoxicity preceded by increases in intracellular contents of glutathione disulfide (GSSG) [Abstract]. Pediatr Res. no. 47: 361A (Published)
  • Rogers LK, Taylor AA, Raya JL, Gest AL, and Smith CV. 2000. Inhibition of fatty streak formation and lipid oxidation by low doses of acetaminophen in hypercholesterolemic rabbits [Abstract]. Toxicol Sci. no. 54: 348 (Published)
  • Rogers LK. Valentine CJ, Szczpyka M, Smith CV. 2000. Effects of hepatotoxic doses of acetaminophen and furosemide on tissue concentrations of CoASH and CoASSG in vivo.  Chemical research in toxicology. Vol. 13, no. 9. : 873-82. (IF: 3.2)
  • Fernandes CJ, Raya JL, Rogers LK, and Smith CV. 2000. Oxysterol-induced enhancement of total cellular glutathione (GSH) in Chinese hamster ovary (CHO) cells with enhanced GSH synthetic capacities [Abstract]. Pediatr Res. no. 47: 397A (Published)
  • Smith CV, Gupta S, Rogers LK, Hansen TN, and Welty SE. 2000. Nuclear and Nucleolar expression of glutathione reductase (GR), peroxidase (GPX) and transferase (GST) activities in livers of male and female fischer-344 rats [Abstract]. Free Rad Biol Med. no. 29: S88 (Published)
  • Dugas, TR, Santa Cruz V, Liu H, Rogers LK, Smith CV, and Kanz MF. 2000. Impact of GSH depletion on hepatic CoASH and CoASSG following treatment with 4,4?-methylene dianiline [Abstract]. Toxicol Sci. no. 54: 27-28. (Published)
  • O?Donovan D, Kelley D, Rogers LK, Welty SE, Ramsey PL, and CV Smith. 2000. Effects of Hyperoxia on Lung CoASH and CoASSG Concentrations in the Rat [Abstract]. Toxicol Sci. no. 54: 163 (Published)
  • Welty SE, Hougland KT, Rogers LK, and Smith CV. 2000. Exposure of H441 cells, a pulmonary-derived cell line, to 7-ketocholesterol leads to cytotoxicity, which is preceded by increases in intracellular glutathione disulfide (GSSG) contents [Abstract]. Toxicol Sci. no. 54: 167 (Published)
  • Rogers LK, Taylor AA, Raya JL, Gest AL, and Smith CV. 1999. Acetaminophen lowers fatty streak formation and lipid oxidation in hypercholesterolemic rabbits [Abstract]. Free Rad Biol Med. Vol. 1, no. 27. (November): S108 (Published)
  • O?Donovan D, Kelly D, Rogers LK, Welty SE, Ramsey PL, and Smith CV. 1999. Mitochondrial oxidant stress in hyperoxia: CoASH and CoASSG [Abstract]. Free Rad Biol Med. Vol. 1, no. 27. (November): S96 (Published)
  • Yang CY, Gu ZW, Yang M, Lin SN, Garcia-Prats AJ, Rogers LK, Welty SE, Smith CV. 1999. Selective modification of apoB-100 in the oxidation of low density lipoproteins by myeloperoxidase in vitro.  Journal of lipid research. Vol. 40, no. 4. : 686-98. (IF: 3.4)
  • Taylor AA, Raya J, Rogers LK, Smith CV. 1999. Acetaminophen inhibits fatty streak formation and LDL oxysterols in hypercholesterolemic rabbits. [Abstract]. Circulation 100, Supplement. no. 1: 697 (Published)
  • Tom DJ, Rogers LK, McNaughton KM, Geske RS, DeMayo FJ, Welty SE, and Smith CV. 1999. Mice expressing a Heme Oxygenase-1 (HO-1) transgene driven by a Surfactant Protein C (SPC) promoter are more susceptible to hyperoxic lung injury [Abstract]. Pediatr Res. no. 45: 71A (Published)
  • Wearden ME, Dzidic N, Rogers LK, Vander Straten MC, and Smith CV. 1999. Effect of inhaled nitric oxide and hyperoxia on heme oxygenase expression in neonatal rat lung tissue. [Abstract]. Peadiatr Res. no. 45: 325A (Published)
  • Fernandes CJ, Rogers LK, and Smith CV. 1999. Transient transfection with glutamate-cysteine ligase (GLCL) cDNA attenuate tert-butyl hydroperoxide (tBuOOH) toxicity in Chinese Hamster Ovary (CHO) cells [Abstract]. Pediatr Res. no. 45: 196A (Published)
  • Welty SE, Rogers LK, Tom DJ, McNaughton KM, Geske RS, DeMayo FJ, and Smith CV. 1999. Hyperoxic lung injury is potentiated by SPC promoter-driven expression of an HO-1 transgene in mice [Abstract]. Am J Respir and Crit Care Med. no. 159: 218A (Published)
  • Ramsey PL, Hegemier SE, Dzidic N, Rogers LK, Wearden ME, and Welty SE. 1999. Clara Cell Secreted Protein (CCSP) oxidation in the first week of life is increased in the tracheal fluids of infants that develop Bronchopulmonary Dysplasia [Abstract]. The Toxicologist. no. 48: 127 (Published)
  • Rogers LK, Tom DJ, McNaughton KM, Geske RS, DeMayo FJ, Welty SE, and Smith CV. 1999. Hyperoxic lung injury in vivo is potentiated by SPC promoter-driven expression of HO-1 [Abstract]. The Toxicologist. no. 48: 201. (Published)
  • Wearden ME, Dzidic N, Rogers LK, and Smith CV. 1998. Inhaled nitric oxide increases protein oxidation in rat bronchoalveolar lavage fluids (BAL) and lung subcellular fractions [Abstract]. Pediatr Res. no. 43: 202A (Published)
  • Smith CV, Rogers LK, and Valentine CJ. 1998. Furosemide-induced oxidant stresses in mice are compartmentalized in hepatic mitochondria [Abstract]. Pediatr Res. no. 43: 196A (Published)
  • Smith CV, Rogers LK, Garcia-Prats AJ, Gu ZW, and Yang C-y. 1998. Oxidation of cysteine residues in proteins by myeloperoxidase (MPO) or HOCl in vitro produces sulfenyl or sulfonyl chloride intermediates [Abstract]. Pediatr Res. no. 43: 196A (Published)
  • Wearden ME, Hegemeier S, Dzidic N, Rogers LK, Ramsay PL, Welty SE, and Smith CV. 1998. Oxidative effects in tracheal aspirates from infants receiving inhaled nitric oxide [Abstract]. Free Rad Biol Med. Vol. 1, no. 25: S69 (Published)
  • Fernandes CJ, Rogers LK, McMicken HW, and Smith CV. 1998. Transient transfection with g-glutamylcysteine synthetase (GGCS) light chain cDNA augments stably enhanced GGCS activities of Chinese hamster ovary cells [Abstract]. Pediatr Res. no. 43: 173A. (Published)
  • Perez EM, Rogers LK, Smith CV, and Weisman LE. 1998. Pharmacokinetics of dexamethasone in rats [Abstract]. Pediatr Res. no. 43: 61A (Published)
  • Smith CV, Rogers LK, Gu ZW, and Yang C-y. 1998. Sulfenyl or sulfonyl chloride intermediates in the oxidation of cyst(e)ine residues of apolipoprotein B100 in low density lipoproteins (LDL) by myeloperoxidase (MPO) and HOCl in vitro [Abstract]. Toxicol Sci. no. 42: 302 (Published)
  • Rogers LK, Tom DJ, McNaughton KM, Geske RS, DeMayo FJ, Welty SE, and Smith CV. 1998. SPC promoter-driven expression of HO-1 exacerbates hyperoxic lung injury in vivo [Abstract]. Free Rad Biol Med. Vol. 1, no. 25: S37 (Published)
  • Wearden ME, Dzidic N, Rogers LK, and Smith CV. 1998. Oxidation of lung proteins in rats exposed to inhaled nitric oxide and hyperoxia [Abstract]. Toxicol Sci. no. 42: 68 (Published)
  • Taylor AA, Raya JL, Blatzheim LP, Rogers LK, Pool JL, and Smith CV. 1998. Acetaminophen inhibits both chemical- and cell-mediated human LDL oxidation in vivo and in vitro. [Abstract]. IUPHAR (Published)
  • Rogers LK, Valentine CJ, and Smith CV. 1998. Intramitochondrial oxidant stresses in furosemide-induced hepatic necrosis in vivo [Abstract]. The Toxicologist. no. 42: 151. (Published)
  • Parker KM, Rogers LK, Smith CV, and Welty SE. 1998. Alveolar protein oxidation in hyperoxic lung injury in rats [Abstract]. Pediatr Res. no. 43: 187A (Published)
  • Wearden ME, Hegemier SE, Dzdic N, Rogers LK, Ramsay PL, Welty SE, and Smith CV. 1998. Protein oxidation and nitrotyrosine formation in tracheal aspirate fluids of mechanically ventilated neonates exposed to hyperoxia and/or inhaled nitric oxide [Abstract]. Pediatr Res. no. 43: 203A (Published)
  • Ramsey PL, Hegemier SE, Dzidic N, Rogers LK, Wearden ME, and Welty SE. 1998. Clara cell secreted protein (CCSP) oxidation in the first week of life is increased in the tracheal fluids of infants that develop bronchopulmonary dysplasia [Abstract]. Pediatrics. Vol. 3, no. 102: A756 (Published)
  • Valentine CJ, Rogers LK, and Smith CV. 1997. Intramitochondrial oxidant stresses in furosemide-induced hepatic necrosis in vivo. [Abstract]. Oxygen. no. 97: 105 (Published)
  • Smith CV, Rogers LK, Gu ZW, and Yang C-y. 1997. Oxidation of cyst(e)ine residues of apolipoprotein B100 in low density lipoproteins by myeloperoxidase and HOCl in vitro. [Abstract]. Oxygen. no. 97: 103 (Published)
  • Yang CY, Gu ZW, Yang H, Yang M, Wiseman WS, Rogers LK, Welty SE, Katta V, Rohde MF, Smith CV. 1997. Oxidation of bovine beta-casein by hypochlorite.  Free radical biology & medicine. Vol. 22, no. 7. : 1235-40. (IF: 3.5)
  • Rogers LK, Garcia-Prats AJ, Gu ZW, and Yang C-y, Smith CV. 1997. Oxidation of glutathione by myeloperoxidase and HOCl in vitro [Abstract]. Oxygen. no. 97: 105 (Published)
  • Fernandes CJ, Rogers LK, McMicken HW, Elliston JF, and Smith CV. 1997. Stable transfection with cDNAs for g-glutamylcysteine synthetase heavy chain (GGCS-Hc) protects Chinese hamster Ovary (CHO) cells against t-butyl hydroperoxide (t-BuOOH) or diquat (DQ) toxicity. [Abstract]. Pediatr Res. no. 41: 148A. (Published)
  • McNatt SA, Rogers LK, Tamura T, Wu B, Welty SE, and Smith CV. 1997. Mitochondrial and nuclear DNA alterations caused by hepatotoxic doses of acetaminophen (AP) in mice. [Abstract]. Pediatr Res. no. 41: 164A (Published)
  • Rogers LK, Yang CY, Garcia-Pratts A, Welty SE, and Smith CV. 1997. Oxidation of b-casein by HOCl in vitro [Abstract]. Fund Appl Toxicol. no. 36: 110. (Published)
  • Wearden ME, Dzidic N, Rogers LK, and Smith CV. 1997. Protein oxidation in lungs of rats exposed to inhaled nitric oxide and hyperoxia [Abstract]. Oxygen. no. 97: 87 (Published)
  • Gupta S, Rogers LK, Taylor SK, Smith CV. 1997. Inhibition of carbamyl phosphate synthetase-I and glutamine synthetase by hepatotoxic doses of acetaminophen in mice.  Toxicology and applied pharmacology. Vol. 146, no. 2. : 317-27. (IF: 2.1)
  • Yang C-y, Gu ZW, Rogers LK, and Smith CV. 1997. Highly selective modification of apolipoprotein B100 in low density lipoproteins by myeloperoxidase in vitro [Abstract]. Circulation (Supplement). no. 96: 1-105. (Published)
  • Gupta S, Kleiner HE, Rogers LK, Lau SS, Smith CV. 1997. Redox stress andhepatic DNA fragmentation induced by diquat in vivo are not accompanied by increased 8-hydroxydeoxyguanosine contents.  Redox Report. Vol. 3. : 31-39. (IF: 1.1)
  • Gupta S, Taylor SK, Rogers LK, and Smith CV. 1997. Dose-dependent inhibition of hepatic carbamyl phosphate synthetase-I (CPS-I) and glutamine synthetase (GS) activities by acetaminophen (AP) in mice [Abstract]. Fund Appl Toxicol. no. 36: 210 (Published)
  • Rogers LK, Moorthy B, Smith CV. 1997. Acetaminophen binds to mouse hepatic and renal DNA at human therapeutic doses.  Chemical research in toxicology. Vol. 10, no. 4. : 470-6. (IF: 2.9)
  • Fernandes CJ, Nguyen UT-L, Rogers LK, Elliston JF, and Smith CV. 1997. Overexpression of g-glutamylcysteine synthetase heavy chain cDNA does not protect Chinese hamster ovary cells from growth inhibition in hyperoxia. [Abstract]. Pediatr Res. no. 41: 148A. (Published)
  • Rogers LK, Garcia-Prats AJ, Gu ZW, and Yang C-y, Smith CV. 1997. Oxidation of glutathione by myeloperoxidase and HOCl in vitro [Abstract]. Oxygen. no. 97: 103 (Published)
  • Boydstun II, McNatt SA, Hu MA, Rogers LK, and Smith CV. 1996. Amphotericin B (AMPHB) renal injury in rats and protein thiol status [Abstract]. Fund Appl Toxicol. no. 30: 303-304. (Published)
  • Fernandes CJ, Nguyen UT-L, Rogers LK, Elliston JF, and Smith CV. 1996. Genetic enhancement of glutathione (GSH) synthetic capacity protects mammalian cells from t-BuOOH toxicity [Abstract]. Oxygen. no. 96: 88A (Published)
  • Fernandes CJ, Stewart KD, Nguyen UT-L, Rogers LK, and Smith CV. 1996. Transfection with cNDAs for ?-glutamylcysteine synthetase (GGCS) in mammalian cells enhances glutathione synthetic capacity [Abstract]. Pediatr REs. no. 39: 208A (Published)
  • Smith CV, Gupta S, Kleiner H, Rogers LK, and Lau SS. 1996. DNA fragmentation caused by reactive oxygen species in vivo without increased 8-OH-dG contents [Abstract]. Pediatr Res. no. 39: 79A (Published)
  • Rogers LK, and Smith CV. 1996. Acetaminophen (AP) at therapeutic doses (for humans) covalently binds to DNA in mice. [Abstract]. Fund Appl Toxicol. no. 30: 1446 (Published)
  • Rogers LK, and Smith CV. 1996. Therapeutic doses of acetaminophen (AP) alkylate mouse hepatic and renal DNA. [Abstract]. Pediatr Res. no. 39: 78A (Published)
  • Fernandes CJ, Stewart KD, Nguyen UT-L, Rogers LK, and Smith CV. 1996. Enhancement of glutathione synthetic capacity in mammalian cells by transfection with cDNA for g-glutamylcysteine synthetase (GGCS) [Abstract]. FASEB J. no. 10: A440. (Published)
  • Boydstun II, McNatt SA, Hu MI, Rogers LK, and Smith CV. 1996. Glutathione and protein thiol status in renal injury by amphotericin B (AMPH) in rats [Abstract]. Pediatr Res. no. 39: 358A (Published)
  • Gupta S, Kleiner H, Rogers LK, and Smith CV. 1996. Diquat causes DNA fragmentation in vivo, but does not increase 8-OH-dG contents [Abstract]. Fund Appl Toxicol. no. 30: 69 (Published)
  • Ramsay PL, Wafelman LS, Rogers LK, Smith CV, and Welty SE. 1996. The effects of dexamethasone (DEX) and hyperoxia on the glutathione (GSH) system in rats. [Abstract]. Pediatr Res. no. 39: 347A (Published)
  • Blomkalns AL, Rogers LK, Tamura T, Tonoki H, Hansen TN, and Smith CV. 1995. Toxicity of acetaminophen, N-acetyl-p-benzoquinone imine (NAPQI) and diquat in Chinese hamster ovary (CHO) cells with genetically modified glutathione reductase (GR) activities [Abstract]. Pediatr Res. no. 37: 75A (Published)
  • Rogers LK, and Smith CV. 1995. HPLC analysis of glutathione (GSH) and related biological thiols and disulfides. [Abstract]. The Toxicologist. no. 15: 153 (Published)
  • Smith CV, Gupta S, and Rogers LK. 1995. Hyperammonemia caused by acetaminophen (AP): Evidence for alkylation of thiols on hepatic carbamyl phosphate synthetase-I (CPS I). [Abstract]. Internat. Congress of Toxicol. no. Vll: 12-PD-2. (Published)
  • Smith CV, Blomkalns AL, Rogers LK, Tamura T, Tonoki H, and Hansen TN. 1995. N-Acetyl-p-benzoquinone imine (NAPQI) toxicity in Chinese hamster ovary (CHO) cells with genetically modified glutathione reductase (GR) activities [Abstract]. FASEB J. no. 9: A694 (Published)
  • Boydstun II, McNatt SA, Rogers LK, and Smith CV. 1995. Protein thiol status in renal injury by amphotericin (AMPH) in rats [Abstract]. J Amer Soc Nephrol. no. 6: 995 (Published)
  • Smith CV, Blomkalns AL, Rogers LK, Tamura T, Tonoki H, and Hansen TN. 1995. Toxicity of N-acetyl-p-benzoquinone imine (NAPQI) and diquat in Chinese hamster ovary (CHO) cells [Abstract]. Toxicologist. no. 15: 151 (Published)
  • Smith CV, Gupta S, and Rogers LK. 1995. Depletion of protein thiol content and inhibition of hepatic carbamyl phosphate synthetase I (CPS I) in mice by hepatotoxic doses of acetaminophen (AP) [Abstract]. Pediatr Res. no. 37: 79A (Published)
  • Wafelman LS, Rogers LK, Awasthi S, and Smith CV. 1995. Exogenous iron disturbs protection against reactive oxygen species (ROS) mediated hepatic necrosis in rats [Abstract]. Pediatr Res. no. 37: 133A (Published)
  • Blomkalns AL, Rogers LK, Tamura T, Tonoki H, Hansen TN, and Smith CV. 1995. Toxicity of N-acetyl-p-benzoquinone imine (NAPQI) and diquat in Chinese hamster ovary (CHO) cells [Abstract]. The Toxicologist. no. 15: 300 (Published)
  • Smith CV, Gupta S, Kleiner HE, Rogers LK, and Lau SS. 1995. Redox stresses and DNA fragmentation induced by diquat in vivo without increases in 8-hydroxydeoxyguanosine (8OHdG) [Abstract]. Oxygen. no. 95: 66 (Published)
  • Tamura T, McMicken HW, Rogers LK, Smith CV, and Hansen TN. 1995. Glutathione (GSH)/glutathione disulfide (GSSG) rations in Chinese hamster ovary (CHO) cells transfected with human glutathione reductase (GR) cDNA [Abstract]. FASEB J. no. 9: A494 (Published)
  • Gupta S, Rogers LK, and Smith CV. 1995. Inhibition of carbamyl phosphate synthase I (CPS I) by hepatotoxic doses of acetaminophen (AP) in mice [Abstract]. Toxicologist. no. 15: 151 (Published)
  • Gupta S, Rogers LK, and Smith CV. 1995. Inhibition of carbamyl phosphate synthase I (CPS I) by hepatotoxic doses of acetaminophen (AP) in mice [Abstract]. Toxic Subst Mech. no. 14: 214 (Published)
  • Smith CV, Blomkalns AL, Rogers LK, Tamura T, Tonoki H, and Hansen TN. 1995. Diquat, acetaminophen, and N-acetyl-p-benzoquinone imine (NAPQI) toxicity in Chinese hamster ovary (CHO) cells with decreased glutathione reductase (GR) activities [Abstract]. Internat Congress of Toxicol. no. 88: 8. (Published)
  • Chang A, McQuinn TC, Rogers LK, and Smith CV. 1994. DNA alterations induced by acetaminophen metabolites in vivo and in vitro [Abstract]. Tox Subst J. no. 13: 208 (Published)
  • Gupta S, Rogers LK, and Smith CV. 1994. Involvement of lysosomal exocytosis in the biliary excretion of iron and oxidized proteins in rats [Abstract]. Tox Subst J. no. 13: 218 (Published)
  • Gupta S, Rogers LK, and Smith CV. 1994. Biliary excretion of oxidized proteins, nonheme iron and lysosomal enzymes by diquat and acetaminophen treated rats [Abstract]. FASEB J. no. 8: A672 (Published)
  • Wafelman LS, Rogers LK, Gyurasics AG, Gupta S, and Smith CV. 1994. Evidence for a critical role of iron chelates in oxidative hepatic injury in rats [Abstract]. Pediatr Res. no. 36: 43A (Published)
  • Gyurasics A, Kelley DK, Rogers LK, Welty SE, Hansen TN, and Smith CV. 1994. Mitochondrial compartmentalization of hyperoxic stresses investigated by measurement of Coenzyme A (CoASH) and CoASSG in rat lungs [Abstract]. Pediatr Res. no. 35: 392A (Published)
  • Gupta S, Rogers LK, Smith CV. 1994. Biliary excretion of lysosomal enzymes, iron, and oxidized protein in Fischer-344 and Sprague-Dawley rats and the effects of diquat and acetaminophen.  Toxicology and applied pharmacology. Vol. 125, no. 1. : 42-50. (IF: 2.1)
  • Smith CV, Rogers LK, Rabin RL, Maldonado YA, Herzenberg LA, Herzenberg LA, and Petru A. 1994. Effects of human immunodeficiency virus (HIV) infection on plasma glutathione status in children [Abstract]. Pediatr Res. no. 35: 196A (Published)
  • Chang A, McQuinn TC, Rogers LK, and Smith CV. 1994. Acetaminophen metabolite alterations of DNA in vivo and in vitro [Abstract]. Pediatr Res. no. 35: 82A (Published)
  • Gomez MR, Benzick A, Rogers LK, Heird WC, Smith CV. 1994. Attenuation of acetaminophen hepatotoxicity in mice as evidence for the bioavailability of the cysteine in D-glucose-L-cysteine in vivo.  Toxicology letters. Vol. 70, no. 1. : 101-8. (IF: 1.1)
  • Benzick AE, Reddy SL, Gupta S, Rogers LK, Smith CV. 1994. Diquat- and acetaminophen-induced alterations of biliary efflux of iron in rats.  Biochemical pharmacology. Vol. 47, no. 11. : 2079-85. (IF: 2.4)
  • Smith CV, Szczpyka M, Rogers LK, Kelley DK, Gilbert HF, Orkisewski RS. 1993. Measurement of CoASH and CoASSG in freeze-clamped tissue as an index of intramitochondrial redox status in vivo [Abstract]. FASEB J. no. 7: A36 (Published)
  • Gupta S, Rogers LK, Smith CV. 1993. Effects of acetaminophen (AP) and diquat on lysosomal exocytosis in rats [Abstract]. FASEB J. no. 7: A37 (Published)
  • Smith CV, Rogers LK, Szczpyka M, and Gilbert HF. 1993. Intramitochondrial redox status in vivo as assessed by measurement of CoASH and CoASSG in freeze-clamped tissue. [Abstract]. Free Rad Biol Med. no. 15: 483 (Published)
  • Gomez MR, Rogers LK, Smith CV, Heird WC. 1993. The fate of parenteral D-glucose-L-cysteine (DGC) in infants [Abstract]. Pediatr Res. no. 33: 303A. (Published)
  • Smith CV, Szczpyka M, Rogers LK, Gilbert HF, Orkisewski RS. 1993. Intramitochondrial redox status in vivo as assessed by measurement of CoASH and CoASSG in freeze-clamped tissue [Abstract]. Pediatr Res. no. 33: 69A (Published)
  • Smith CV, Gupta S, and Rogers LK. 1993. Lysosomal exocytosis of iron and oxidized proteins in rats treated with diquat. [Abstract]. Free Rad Biol Med. no. 15: 518 (Published)
  • Kelley DK, Szczpyka M, Rogers LK, Gilbert HF, and Smith CV. 1993. CoASH/CoASSG as a measure of mitochondrial redox status in vivo and depletion of CoASH by acetaminophen (AP) [Abstract]. The Toxicologist. no. 13: 240 (Published)
  • Smith CV, Gupta S, Rogers LK. 1993. Lysosomal exocytosis of iron and protein in rats and the effects of acetaminophen (AP) and diquat [Abstract]. Pediatr Res. no. 33: 109A. (Published)
  • Smith CV, Chang A, Welty SE, and Rogers LK. 1992. Hepatotoxic doses of acetaminophen cause marked decreases in histone messenger RNA in mouse liver [Abstract]. Pediatr Res. no. 31: 117A (Published)
  • Smith CV, Gupta S, Chang A, and Rogers LK. 1992. Redistribution of hepatic iron in diquat-induced oxidant stress and hepatic necrosis in vivo. [Abstract]. Pediatr Res. no. 31: 117A (Published)
  • Smith CV, Gupta S, Chang A, and Rogers LK. 1992. Diquat-induced redistribution of hepatic iron in rats [Abstract]. The Toxicologist. no. 12: 76 (Published)
  • Smith CV, Chang A, Welty SE, and Rogers LK. 1992. Hepatotoxic doses of acetaminophen cause marked decreases in histone messenger RNA in mouse liver [Abstract]. FASEB J. no. 6: A1274. (Published)
  • Smith CV, Welty SE, Hansen TN, Rogers LK, Chang A, Benzick AE, and Montgomery CA. 1992. Investigation of acetaminophen-induced vascular congestion in mice and observation of a marked decrease in histone messenger RNA [Abstract]. International Congress of Toxicology, Rome, Toxicol Lett Supplement. no. 261 (Published)
  • Gupta S, Chang A, Rogers LK, and Smith CV. 1992. Diquat-induced subcellular redistribution of hepatic iron in rats [Abstract]. FASEB J. no. 6: A1056 (Published)
  • Gomez MR, Benzick AE, Rogers LK, Heird WC, and Smith CV. 1992. Bioavailability in vivo of a glucose-cysteine adduct formed in vitro in parenteral nutrition mixtures [Abstract]. FASEB J. no. 6: A1216 (Published)
  • Smith CV, Gupta S, Chang A, Benzick AE, and Rogers LK. 1992. Diquat-induced oxidant stress and hepatic necrosis in rats in vivo and the redistribution of hepatic iron. [Abstract]. VI International congress of Toxicology, Rome, Toxicol Lett Supplement. no. 219 (Published)
  • Brown SA; Rogers LK; Dunn JK; Gotto AM Jr; Patsch W. 1990. Development of cholesterol homeostatic memory in the rat is influenced by maternal diets.  Metabolism: clinical and experimental. Vol. 39, no. 5. : 468-73. (IF: 1.7)
  • McDaniel LS, Rogers LK, Hill WE. 1978. Survival of recombination -deficient mutants of Escherichia coli during incubation with nalidixic acid.  Journal of Bacteriology. Vol. 134. : 1195-1198. (IF: 3.6)
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000