Lynette K. Rogers, PhD :: Nationwide Children's Hospital, Columbus, Ohio

Lynette K. Rogers, Ph.D.

Lynette K. Rogers, Ph.D.

Center for Perinatal Research
Principal Investigator

Principal Investigator

Neonatology Fellowship

Contact Information

The Research Institute at Nationwide Children's Hospital, Center for Perinatal Research
575 Children's Crossroads, Research Building III, 6th Floor
Columbus, Ohio 43215 [ map ]
PH: (614) 355-6715
Email Me


Lynette K. Rogers, Ph.D. is a Principal Investigator in the Center for Perinatal Research at The Research Institute at Nationwide Children’s Hospital. She is an Associate Professor at The Ohio State University College of Medicine. Dr. Rogers NIH-funded research focuses on lung injury and growth deficits in preterm infants.
The ultimate goal of the Rogers lab is to better understand the consequences of premature birth and strive to develop efficacious treatments that would decrease morbidities in prematurely born infants. Many preterm births are a result of maternal inflammation and once born, the infant often requires oxygen therapy for survival. The combination of inflammatory stimuli results in a much more severe pathophysiology with more critical and long lasting morbidities. Our studies have identified several epigenetic markers that are affected by one or both of these adverse conditions and may be linked to further disease development. These include microRNAs, upregulation of methylation enzymes, and methylation of key genes. These markers have been identified in infants diagnosed with Bronchopulmonary dysplasia (BPD) and in our mouse model of combined inflammatory exposures. We are working to better understand the mechanisms driving these alterations, how they affect the morbidities observed, and to identify pathways that can be targeted for interventions.


  • Female

Languages Spoken:

  • English

Research Interests

Research Center:

Areas of Interest:

  • The ultimate goal of my lab is to identify the causes of premature birth, help design treatments that would prevent prematurity, and strive to help develop efficacious treatments that would decrease morbidities in prematurely born infants. The research efforts in my lab are two fold. First, we are working to identify biomarkers early in the life of a premature infant that would predict outcomes and development of diseases and better understand the mechanisms involved in these disease processes. We use a broad scope of analytical techniques to identify alterations in proteins and lipids in both animal models of premature birth as well as human studies. Secondly, our animal models focus on inflammation resolution. Inflammation is a large component of diseases associated with prematurity, specifically those that involve the lung. Impaired inflammatory resolution may, in part, be responsible for the progression and chronic state of lung diseases in the premature infant. We are working to develop interventions that would improve inflammatory resolution in a newborn mouse model.

Education and Training

Undergraduate School

  • University of Southwestern Louisiana
    Date Completed: 06/30/1977

Post Doctoral

  • The Ohio State University
    Date Completed: 06/30/2004

Professional Experience


  • Associate Professor (with tenure), Department of Pediatrics, Ohio State University, Columbus, Ohio


  • Principal Investigator, Columbus Children’s Research Institute, Columbus, Ohio


  • Assistant Professor, Department of Pediatrics, Ohio State University, Columbus, Ohio


  • Senior Research Scientist, Columbus Children’s Research Institute, Columbus, Ohio


  • Sr. Research Associate, Columbus Children’s Research Institute, Columbus, Ohio


  • Research Assistant, Department of Pediatrics, Baylor College of Medicine, Houston Texas


  • Research Technician, Shell Oil Co., Houston, Texas


  • Research Technician, Department of Medicine, Baylor College of Medicine, Houston, Texas


  • Research Technician, Exxon Research and Development Co., Baytown, Texas


  • Research Technician, University of Texas Health Science Center, Houston, Texas


  • Trittmann,Jennifer,K; Gastier-Foster,Julie,M; Zmuda,Erik,J; Frick,Jessica; Rogers,Lynette,K; Vieland,Veronica,J; Chicoine,Louis,G; Nelin,Leif,D. 2016. A single nucleotide polymorphism in the dimethylarginine dimethylaminohydrolase gene is associated with lower risk of pulmonary hypertension in bronchopulmonary dysplasia.  ACTA PAEDIATRICA. Vol. 105, no. 4. (April): E170-E175.
  • Hilbert,Tobias; Duerr,Georg,Daniel; Hamiko,Marwan; Frede,Stilla; Rogers,Lynette; Baumgarten,Georg; Hoeft,Andreas; Velten,Markus. 2016. Endothelial permeability following coronary artery bypass grafting: an observational study on the possible role of angiopoietin imbalance.  CRITICAL CARE. Vol. 20, no. March: e51.
  • Ali,Mehboob; Heyob,Kathryn; Rogers,Lynette,K. 2016. DHA Suppresses Primary Macrophage Inflammatory Responses via Notch 1/Jagged 1 Signaling.  SCIENTIFIC REPORTS. Vol. 6, no. March: e22276.
  • MARTINEZ,J,T; Rogers,L,K; Kellogg,C; Iazbik,M,C; Couto,C,G; Pressler,B,M; Hoepf,T,M; Radin,M,J. 2016. Plasma Vasoprotective Eicosanoid Concentrations in Healthy Greyhounds and Non-Greyhound Dogs.  JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 30, no. 2. (March): 583-590.
  • Geraghty,Sheela,R; McNamara,Kelly; Kwiek,Jesse,J; Rogers,Lynette; Klebanoff,Mark,A; Augustine,Molly; Keim,Sarah,A. 2015. Tobacco Metabolites and Caffeine in Human Milk Purchased via the Internet.  BREASTFEEDING MEDICINE. Vol. 10, no. 9. (November): 419-424.
  • Rogers LK, Robbins M, Dakhlallah D, Yang Z, Lee LJ, Mikhail M, Nuovo G, Pryhuber GS, McGwin G, Marsh CB, Tipple TE. 2015. microRNA-17~92 Cluster Expression is Attenuated in Bronchopulmonary Dysplasia.  Annals of the American Thoracic Society. Vol. 10, no. October: 1506-13.
  • Ali,Mehboob; Heyob,Kathryn,M; Velten,Markus; Tipple,Trent,E; Rogers,Lynette,K. 2015. DHA suppresses chronic apoptosis in the lung caused by perinatal inflammation.  AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. Vol. 309, no. 5. (September): L441-L448.
  • Ali M, Heyob K, Rogers LK. 2015. DHA-mediated regulation of lung cancer cell migration is not directly associated with Gelsolin or Vimentin expression.  Life Sciences. Vol. 155, no. June: 1-9.
  • Velten, M and Rogers, LK. 2015. Linkage Between in Utero Environmental Changes and Preterm Birth. In The Epigenome and Developmental Origins of Health and DIsease. Edited by Rosenfeld, C. S.. London: Academic Press.
  • Ali,Mehboob; Rogers,Lynette,K; Pitari,Giovanni,M. 2015. Serine phosphorylation of vasodilator-stimulated phosphoprotein (VASP) regulates colon cancer cell survival and apoptosis.  LIFE SCIENCES. Vol. 123, no. February: 1-8.
  • Trittmann,Jennifer,K; Peterson,Eric; Rogers,Lynette,K; Chen,Bernadette; Backes,Carl,H; Klebanoff,Mark,A; Nelin,Leif,D. 2015. Plasma Asymmetric Dimethylarginine Levels Are Increased in Neonates with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension.  JOURNAL OF PEDIATRICS. Vol. 166, no. 2. (February): 230-233.
  • Augustine MA, Bonny AE, Rogers LK. 2014. Medroxyprogesterone Acetate and Progesterone Measurement in Human Serum: Assessments of Contraceptive Efficacy.  J of Analytical & Bioanalytical Techniques. Vol. 5, no. S5:005. (October): 377-384.
  • Britt,Rodney,D; Velten,Markus; Locy,Morgan,L; Rogers,Lynette,K; Tipple,Trent,E. 2014. The Thioredoxin Reductase-1 Inhibitor Aurothioglucose Attenuates Lung Injury and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome.  ANTIOXIDANTS & REDOX SIGNALING. Vol. 20, no. 17. (June): 2681-2691.
  • Bonny,Andrea,E; Lange,Hannah,LH; Rogers,Lynette,K; Gothard,Dave,M; Reed,Michael,D. 2014. A pilot study of depot medroxyprogesterone acetate pharmacokinetics and weight gain in adolescent females.  CONTRACEPTION. Vol. 89, no. 5. (May): 357-360.
  • Velten,Markus; Gorr,Matthew,W; Youtz,Dane,J; Velten,Christina; Rogers,Lynette,K; Wold,Loren,E. 2014. Adverse perinatal environment contributes to altered cardiac development and function.  AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. Vol. 306, no. 9. (May): H1334-H1340.
  • Rogers, LK , Lucchesi PA. 2014. Stress adaptation and the resilience of youth: fact or fiction?.  Physiology. Vol. 29, no. May: e156.
  • Rodney D. Britt Jr., Markus Velten, Trent E.Tipple, Leif D. Nelin, Lynette K. Rogers. 2014. Cyclooxygenase-2 in Newborn Hyperoxic Lung Injury.  Free Radical Biology and Medicine. Vol. 61C, no. April: 502-511.
  • Velten,Markus; Britt,Rodney,D; Heyob,Kathryn,M; Tipple,Trent,E; Rogers,Lynette,K. 2014. Maternal Dietary Docosahexaenoic Acid Supplementation Attenuates Fetal Growth Restriction and Enhances Pulmonary Function in a Newborn Mouse Model of Perinatal Inflammation.  JOURNAL OF NUTRITION. Vol. 144, no. 3. (March): 258-266.
  • Graf,Amanda,E; Haines,Krista,M; Pierson,Christopher,R; Bolon,Brad,N; Houston,Ronald,H; Velten,Markus; Heyob,Kathryn,M; Rogers,Lynette,K. 2014. Perinatal inflammation results in decreased oligodendrocyte numbers in adulthood.  LIFE SCIENCES. Vol. 94, no. 2. (January): 164-171.
  • Rogers,Lynette,K; Graf,Amanda,E; Bhatia,Anisha; Leonhart,Karen,L; Oza-Frank,Reena. 2013. Associations between Maternal and Infant Morbidities and sRAGE within the First Week of Life in Extremely Preterm Infants.  PLOS ONE. Vol. 8, no. 12. (December): ee82537.
  • Augustine MS and Rogers LK. 2013. Measurement of Arginine Metabolites: Regulators of Nitric Oxide Metabolism. In Current Protocols in Toxicology. Hoboken, NJ: Wiley.
  • Sharkey LC, Radin MJ, Heller L, Rogers LK, Tobias A, Matise I, Wang Q, Apple F, McCune SA. 2013. Differential Cardiotoxicity in Response to Chronic Doxorubicin Treatment in Male Spontaneous Hypertension-Heart Failure (SHHF), Spontaneously Hypertensive (SHR), and Wistar Kyoto (WKY) rats.  Toxicology and Applied Pharmacology. Vol. 273, no. 1. (November): 47-57.
  • Jing Yan, Melissa M. Ralston, Xiaomei Meng, Kathleen D. Bongiovanni, Amanda L. Jones, Rainer Benndorf, Leif D. Nelin, Lynette K. Rogers, Charles V. Smith, Yusen Liu. 2013. Glutathione Reductase Is Essential for Host Defense against Bacterial Infection.  Free Radical Biology and Medicine. Vol. 61C, no. April: 320-332.
  • Valentine CJ, Morrow G, Pennell M, Morrow AL, Hodge A, Haben-Bartz A, Collins K, Rogers LK. 2013. Randomized Controlled Trial of Docosahexaenoic Acid Supplementation in Midwestern U.S. Human Milk Donors.  Breast Feeding Medicine. Vol. 8, no. 1. (February): 86-91.
  • Raffay,Thomas,M; Locy,Morgan,L; Hill,Cynthia,L; Jindal,Nik,S; Rogers,Lynette,K; Welty,Stephen,E; Tipple,Trent,E. 2013. Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobins and Annexin A1.  BIOMED RESEARCH INTERNATIONAL. Vol. 2013, no. January: e408485.
  • Rogers LK, Valentine CJ, Keim SA. 2012. DHA Supplementation: Current Implications in Pregnancy and Childhood.  Pharmacol Res. Vol. 70, no. 1. (December): 13-19.
  • Wancket LM, Meng X, Rogers LK, Liu Y. 2012. Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 Protects Mice against Acetaminophen-induced Hepatic Injury.  Toxicologic Pathology. Vol. 40, no. 8. (December): 1095-1105.
  • Locy,Morgan,L; Rogers,Lynette,K; Prigge,Justin,R; Schmidt,Edward,E; Arner,Elias,SJ; Tipple,Trent,E. 2012. Thioredoxin Reductase Inhibition Elicits Nrf2-Mediated Responses in Clara Cells: Implications for Oxidant-Induced Lung Injury.  ANTIOXIDANTS & REDOX SIGNALING. Vol. 17, no. 10. (November): 1407-1416.
  • Velten,Markus; Britt,Rodney,D; Heyob,Kathryn,M; Welty,Stephen,E; Eiberger,Britta; Tipple,Trent,E; Rogers,Lynette,K. 2012. Prenatal inflammation exacerbates hyperoxia-induced functional and structural changes in adult mice.  AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. Vol. 303, no. 3. (August): R279-R290.
  • Khandelwal, AR, Hebert, VY, Kleinedler, JJ, Rogers, LK, Ullevig, SL, Asmis, R, Dugas, TR. 2012. Resveratrol and quercetin interact to inhibit neointimal hyperplasia.  Journal of Nutrition. Vol. 142, no. 8. (August): 1487-1494.
  • Rogers LK, Young CM, Pennell ML, Tipple TE, Leonhart KL, Welty SE. 2012. Plasma Lipid Metabolites are Associated with Gestational Age but Not Bronchopulmonary Dysplasia.  Acta Paediatrica. Vol. 101, no. 8. (August): 321-326.
  • Yan,Jing; Meng,Xiaomei; Wancket,Lyn,M; Lintner,Katherine; Nelin,Leif,D; Chen,Bernadette; Francis,Kevin,P; Smith,Charles,V; Rogers,Lynette,K; Liu,Yusen. 2012. Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps.  Journal of immunology (Baltimore, Md. : 1950). Vol. 188, no. 5. (March): 2316-2327.
  • Britt RD, Locy ML, Tipple TE, Nelin LD, Rogers LK. 2012. Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Mouse Transformed Clara Cells.  Cell Physiol and Biochem. Vol. 29, no. 1-2. (March): 213-22.
  • Tipple TE, Rogers LK. 2012. Methods for the Determination of Plasma or Tissue Glutathione Levels. In Methods in Molecular Biology. Edited by Craig Harris, Jason Hansen. Clifton, NJ: Humana Press.
  • Kleinedler JJ, Orchard E, Foley JD, Rogers LK, Hebert VY, Dugas TR. 2011. A dietary approach to increase in-stent stenosis in a rat model of stenting angioplasty.  Atherosclerosis. Vol. 219, no. 2. (December): 484-91.
  • Velten M, Hutchinson KR, Wold LE, Lucchesi PA, Rogers LK. 2011. Systemic Maternal Inflammation and Neonatal Hyperoxic Induce Remodeling and Impair Left Ventricular Function.  PLoS One. Vol. 6, no. 9. (September): ee24544.
  • Rogers,Lynette,K; Velten,Markus. 2011. Maternal inflammation, growth retardation, and preterm birth: Insights into adult cardiovascular disease.  LIFE SCIENCES. Vol. 89, no. 13-14. (September): 417-421.
  • Cua CL, Rogers LK, Chicoine LG, Augustine M, Jin Y, Nash PL and Nelin LD. 2011. Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.  European Journal of Pediatrics. Vol. 170, no. 7. (July): 859-863.
  • Heyob KM, Rogers LK, Tipple TE, and Welty, SE. 2011. Riboflavin supplementation does not attenuate hyperoxic lung injury in transgenic spc-mthGR mice.  Experimental Lung Research. Vol. 3, no. 37. (April): 155-161.
  • Rogers LK, Valentine CJ, Pennell M, Velten M, Britt RD, Dingess K, Zhao X, Welty SE, and Tipple TE. 2011. Maternal DHA Supplementation Decreases Lung Inflammation in Hyperoxia-Exposed Newborn Mice.  Journal of Nutrition. Vol. 2, no. 141. (February): 214-222.
  • Valentine CJ, Morrow G, Fernandez S, Gulati P, Bartholomew D, Long D, Welty SE, Morrow AL, Rogers LK. 2010. Docosahexaenoic Acid and Amino Acid Contents in Pasteurized Donor Milk are Low for Preterm Infants.  Journal of Pediatrics. Vol. 6, no. 157. (December): 906-910.
  • Farrell MR, Rogers LK, Liu Y, Welty SE, and Tipple TE. 2010. Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activity.  Free Radical Biology and Medicine. Vol. 9, no. 49. (November): 1361-1367.
  • Jiang B, Khandelwal A R, Rogers L K, Shi W, Orr A W, and Dugas T R. 2010. Antiretrovirals Induce Endothelial Dysfunction via Oxidant-Dependent Pathways and Promote Neointimal Hyperplasia in C57BL/6 mice.  Toxicological Sciences. Vol. 2, no. 117. (October): 524-536.
  • Stenger MR, Rose MJ, Joshi MS, Rogers LK, Chicoine LG, Bauer JA, Nelin LD. 2010. Inhaled Nitric Oxide Prevents 3-Nitrotyrosine Formation in the Lungs of Neonatal Mice Exposed to >95% Oxygen.  Lung. Vol. 3, no. 188. (March): 214-227.
  • Velten M, Heyob K M, Rogers L K, Welty S E. 2010. Deficits in Lung Alveolarization and Function After Systemic Maternal Inflammation and Neonatal Hyperoxia Exposure.  J Appl Physiol. Vol. 5, no. 108. (March): 1347-1356.
  • Rogers LK; Tipple TE; Britt RD; Welty SE. 2010. Hyperoxia exposure alters hepatic eicosanoid metabolism in newborn mice.  Pediatric Research. Vol. 67, no. 2. (February): e144.
  • Tipple TE; Welty SE; Nelin LD; Hansen JM; Rogers LK. 2009. Alterations of the thioredoxin system by hyperoxia: implications for alveolar development.  American Journal Of Respiratory Cell And Molecular Biology. Vol. 41, no. 5. (November): e612.
  • Valentine CJ; Fernandez S; Rogers LK; Gulati P; Hayes J; Lore P; Puthoff T; Dumm M; Jones A; Collins K; Curtiss J; Hutson K; Clark K; Welty SE. 2009. Early amino-acid administration improves preterm infant weight.  Journal Of Perinatology: Official Journal Of The California Perinatal Association. Vol. 29, no. 6. (June): e428.
  • Rogers LK; Tipple TE; Nelin LD; Welty SE. 2009. Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen.  Pediatric Research. Vol. 65, no. 1. (January): e33.
  • Heyob KM, Rogers LK, Welty SE. 2008. Glutathione Reductase Targeted to Type ll Cells Does Not Protect Mice from Hyperoxic Lung Injury.  Am J Resp Mol Cell Biol.. Vol. 39, no. 6. (January): 683-688.
  • Park MS, Rieger-Fackeldey E, Schanbacher BL, Cook AC, Bauer JA, Rogers LK, Hansen TN, Welty SE, Smith CV. 2007. Altered Expressions of Fibroblast Growth Factor Receptors and Alveolarization in Neonatal Mice Exposed to 85% Oxygen.  Pediatric Research. Vol. 6, no. 62. (January): 652-657.
  • Tipple TE, Welty SE, Rogers LK, Hansen TN, Choi YE, Kehrer JP, Smith CV. 2007. Thioredoxin-related mechanisms in hyperoxic lung injury in mice.  American Journal of Respiratory Cell and Molecular Biology. Vol. 37, no. 4. (January): 405-413.
  • Rogers, Lynette, K; Leinweber, Barbara, L; Smith, Charles V. 2006. Detection of reversible protein thiol modifications in tissues.  Analytical biochemistry. Vol. 358, no. 2. (January): 171-84.
  • Malleske, Daniel, T; Rogers, Lynette, K; Velluci, Sean, M; Young, Tamara, L; Park, Min, S; Long, Donald, W; Welty, Stephen, E; Smith, Charles, V; Nelin, Leif D. 2006. Hyperoxia increases hepatic arginase expression and ornithine production in mice.  Toxicology and applied pharmacology. Vol. 215, no. 1. (January): 109-17.
  • Rogers LK; Bates CM; Welty SE; Smith CV. 2006. Diquat induces renal proximal tubule injury in glutathione reductase-deficient mice.  Toxicology and applied pharmacology. Vol. 217, no. 3. (January): 289-98.
  • Rogers, Lynette, K; Tamura, Toshiya; Rogers, Bryan, J; Welty, Stephen, E; Hansen, Thomas, N; Smith, Charles V. 2004. Analyses of glutathione reductase hypomorphic mice indicate a genetic knockout.  Toxicological sciences. Vol. 82, no. 2. (January): 367-73.
  • Jopperi-Davis, Katrina, S; Park, Min Soo; Rogers, Lynette, K; Backes, Carl H Jr; Lim, In Kyoung; Smith, Charles V. 2004. Compartmental inhibition of hepatic glutathione reductase activities by 1,3-bis(2-chloroethyl)-N-nitrosourea (BCNU) in Sprague-Dawley and Fischer-344 rats.  Toxicology letters. Vol. 147, no. 3. (January): 219-28.
  • Rogers LK, Smith CV. 2003. Coenzyme A and coenzyme A-glutathione disulfide measurements by HPLC. In Current Protocols in Toxicology. Edited by Maines MD. New York City, NY: John Wiley and Sons.
  • Jenniskens,F,A; Jopperi-Davis,K,S; Walters,L,C; Schorr,E,N; Rogers,L,K; Welty,S,E; Smith,C,V. 2002. Effects of fasting on coenzyme A and relate tissue contents of intermediates in rats.  PEDIATRIC RESEARCH. Vol. 52, no. 3. (September): 437-442.
  • Jenniskens, Floor, A; Jopperi-Davis, Katrina, S; Walters, Lauren, C; Schorr, Erica, N; Rogers, Lynette, K; Welty, Stephen, E; Smith, Charles V. 2002. Effects of fasting on tissue contents of coenzyme A and related intermediates in rats.  Pediatric research. Vol. 52, no. 3. (January): 437-42.
  • O'Donovan, Donough, J; Rogers, Lynette, K; Kelley, Donald, K; Welty, Stephen, E; Ramsay, Patricia, L; Smith, Charles V. 2002. CoASH and CoASSG levels in lungs of hyperoxic rats as potential biomarkers of intramitochondrial oxidant stresses.  Pediatric research. Vol. 51, no. 3. (January): 346-53.
  • Fernandes, Caraciolo, J; Rong, Liang; Tamura, Toshiya; Stewart, Kerry, D; Rogers, Lynette, K; McMicken, Harilyn, W; Elliston, Jonathan, F; Hansen, Thomas, N; Smith, Charles V. 2002. Stable transfection of Chinese hamster ovary cells with glutamate-cysteine ligase catalytic subunit cDNA confers increased resistance to tert-butyl hydroperoxide toxicity.  Toxicology letters. Vol. 136, no. 2. (January): 107-20.
  • O'Donovan DJ, Kelley DK, Rogers LK, Welty SE, Ramsay PL, Smith CV. 2002. Mitochondrial oxidant stress iin hyperoxia:CoASH and CoASSG.  Pediatr research. Vol. 51, no. January: 346-353.
  • Rogers, Lynette, K; Gupta, Sanjiv; Welty, Stephen, E; Hansen, Thomas, N; Smith, Charles V. 2002. Nuclear and nucleolar glutathione reductase, peroxidase, and transferase activities in livers of male and female Fischer-344 rats.  Toxicological sciences : an official journal of the Society of Toxicology. Vol. 69, no. 1. (January): 279-85.
  • Wong YL, Smith CV, McMicken HW, Rogers LK, Welty SE. 2001. Mitochondrial thiol status in the liver is altered by exposure to hyperoxia.  Toxicology letters. Vol. 123, no. 2-3. (January): 179-93.
  • Rogers LK. Valentine CJ, Szczpyka M, Smith CV. 2000. Effects of hepatotoxic doses of acetaminophen and furosemide on tissue concentrations of CoASH and CoASSG in vivo.  Chemical research in toxicology. Vol. 13, no. 9. (January): 873-82.
  • Yang CY, Gu ZW, Yang M, Lin SN, Garcia-Prats AJ, Rogers LK, Welty SE, Smith CV. 1999. Selective modification of apoB-100 in the oxidation of low density lipoproteins by myeloperoxidase in vitro.  Journal of lipid research. Vol. 40, no. 4. (January): 686-98.
  • Rogers LK, Moorthy B, Smith CV. 1997. Acetaminophen binds to mouse hepatic and renal DNA at human therapeutic doses.  Chemical research in toxicology. Vol. 10, no. 4. (January): 470-6.
  • Yang CY, Gu ZW, Yang H, Yang M, Wiseman WS, Rogers LK, Welty SE, Katta V, Rohde MF, Smith CV. 1997. Oxidation of bovine beta-casein by hypochlorite.  Free radical biology & medicine. Vol. 22, no. 7. (January): 1235-40.
  • Gupta S, Rogers LK, Taylor SK, Smith CV. 1997. Inhibition of carbamyl phosphate synthetase-I and glutamine synthetase by hepatotoxic doses of acetaminophen in mice.  Toxicology and applied pharmacology. Vol. 146, no. 2. (January): 317-27.
  • Gupta S, Kleiner HE, Rogers LK, Lau SS, Smith CV. 1997. Redox stress andhepatic DNA fragmentation induced by diquat in vivo are not accompanied by increased 8-hydroxydeoxyguanosine contents.  Redox Report. Vol. 3, no. January: 31-39.
  • Benzick AE, Reddy SL, Gupta S, Rogers LK, Smith CV. 1994. Diquat- and acetaminophen-induced alterations of biliary efflux of iron in rats.  Biochemical pharmacology. Vol. 47, no. 11. (January): 2079-85.
  • Gupta S, Rogers LK, Smith CV. 1994. Biliary excretion of lysosomal enzymes, iron, and oxidized protein in Fischer-344 and Sprague-Dawley rats and the effects of diquat and acetaminophen.  Toxicology and applied pharmacology. Vol. 125, no. 1. (January): 42-50.
  • Gomez MR, Benzick A, Rogers LK, Heird WC, Smith CV. 1994. Attenuation of acetaminophen hepatotoxicity in mice as evidence for the bioavailability of the cysteine in D-glucose-L-cysteine in vivo.  Toxicology letters. Vol. 70, no. 1. (January): 101-8.
  • Brown SA; Rogers LK; Dunn JK; Gotto AM Jr; Patsch W. 1990. Development of cholesterol homeostatic memory in the rat is influenced by maternal diets.  Metabolism: clinical and experimental. Vol. 39, no. 5. (January): 468-73.
  • McDaniel LS, Rogers LK, Hill WE. 1978. Survival of recombination -deficient mutants of Escherichia coli during incubation with nalidixic acid.  Journal of Bacteriology. Vol. 134, no. January: 1195-1198.
  • Graf AE, Lallier SW, Waidyaratne GR, Thompson MD, Tipple TE, Hester ME, Trask AJ, Rogers LK. Maternal high fat diet exposure is associated with increased hepcidin levels, decreased myelination, and neurobehavioral changes in male offspring.  Brain, Behavior, and Immunity.
  • Thompson MD, Cismowski MJ, Trask AJ, Lallier SW, Graf AE, Rogers LK, Lucchesi PA, Brigstock DR. ENHANCED STEATOSIS AND FIBROSIS IN LIVER OF ADULT OFFSPRING EXPOSED TO MATERNAL HIGH FAT DIET.  Gene Expression.
  • Velten M, Britt RD, Heyob KM, Tipple TE, Rogers LK. Maternal Dietary Docosahexaenoic Acid (DHA) Supplementation Prevents Fetal Growth Restriction and Pulmonary Injury in a Newborn Murine Model of Perinatal Inflammation.  J of Nutrition.
  • Britt RD, Velten M, Locy ML, Rogers LK, Tipple TE. The Thioredoxin Reductase-1 Inhibitor Aurothioglucose Attenuates Lung Injury and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome.  Antioxidants and Redox Signaling.
  • Raffay,Thomas,M; Locy,Morgan,L; Hill,Cynthia,L; Jindal,Nik,S; Rogers,Lynette,K; Welty,Stephen,E; Tipple,Trent,E. Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobins and Annexin A1.  BIOMED RESEARCH INTERNATIONAL.
  • Ali M,Heyob KM, Jacob NK, Rogers LK. Alterative Expression and Localization of Profilin 1/VASPpS157 and Cofilin 1/VASPpS239 Regulates Metastatic Growth and is Modified by DHA Supplementation.  Molecular Cancer Therapeutics.
  • Li Q, Wall SB, Ren C, Velten M, Hill CL, Locy ML, Rogers LK, Tipple TE. Thioredoxin Reductase Inhibition Attenuates Neonatal Hyperoxic Lung Injury and Enhances Nrf2 Activation.  Am J Respir Cell Mol Biol..
  • Lallier SW, Graf AE, Waidyarante GR, Rogers LK. Nurr 1 Expression is Modified by Inflammation in Primary Microglia.  NeuroReports.
  • Bonny AE, Lange HLH, Rogers LK, Gothard DM, Reed MD. A Pilot Study of Depot Medroxyprogesterone Acetate Pharmacokinetics and Weight Gain in Adolescent Females.  Contraception.

Awards, Honors and Organizations

  • Member, Society of Toxicology, 2003-Present
  • Member, American Thoracic Society, 2006-Present
  • Member, American Physiological Society, 2011-Present
  • Member, American Society for Nutrition, 2011-Present
  • Member, American Heart Association, 2011-Present
  • Member, Sigma Xi, 2012-Present
  • Member, Perinatal Research Society, 2013-Present
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000