Jennifer K. Trittmann, MD, MPH

Jennifer Trittmann MD, MPH is Principal Investigator in the Center for Perinatal Research at The Research Institute at Nationwide Children’s Hospital and Neonatology Attending in the Department of Pediatrics. She is an Assistant Professor of Pediatrics at the Ohio State University College of Medicine. Dr. Trittmann’s research focuses on identifying risk factors that predict the evolution of pulmonary hypertension in bronchopulmonary dysplasia, which is the most common chronic lung disease of premature neonates.

Gender:

• Female

Languages Spoken:

• English

Research Center:

• Center for Perinatal Research

Areas of Interest:

• Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease of premature neonates. Pulmonary hypertension (PH) occurs in approximately 30% of BPD patients and is associated with a dramatic increase in morbidity and mortality. There are currently no tests for accurately predicting which BPD patients will develop this life-threatening complication. Nitric oxide (NO) metabolism has been found to be altered in patients with severe BPD. Nitric oxide, an endogenous pulmonary vasodilator, is produced by NO synthase from L-arginine in endothelial cells. In patients with PH from causes other than BPD, circulating levels of L-arginine are decreased, due to decreased endogenous L-arginine production resulting in decreased NO production in the lung. Therefore, the overall hypothesis of our research is that there are single nucleotide polymorphisms (SNPs) and/or metabolites involving the L-arginine/NO pathway that predict the development of PH in BPD, such that effective therapies can be initiated prior to the onset of PH.

Medical School

• Ohio State University College of Medicine
  Date Completed: 06/30/2005

Residency

• Nationwide Children's Hospital
  Date Completed: 06/30/2008

Fellowship

• Nationwide Children's Hospital
  Date Completed: 09/28/2011

Department:

• Pediatrics

Section:

• Neonatology

Speciality:

• Neonatal-Perinatal Medicine
  
• Pediatrics
  

Date of Appointment at Nationwide Children’s Hospital:

• 09/30/2011

• Backes,Carl,H; Reber,Kris,M; Trittmann,Jennifer,KB; Huang,Hong; Tomblin,Jordanna; Moorehead,Pamela,A; Bauer,John,A; Smith,Charles,V; Mahan,John,D. 2011. Fellows as teachers: a model to enhance pediatric resident education.  Medical education online. Vol. 16, no. January.