Infectious Diseases Fellowship Accomplishments :: Nationwide Children's Hospital

Infectious Diseases Fellow Accomplishments

2014-2015 Abstracts

Katherine Moyer, Eleonora Bunsow, Douglas Salamon, MB(ASCP)SV, Amy Leber, PhD, Octavio Ramilo, MD and Asuncion Mejias, MD, PhD. “Implementation of Routine Testing for Human Rhinovirus (HRV) detection and quantitation: Impact of Coinfections, Age and Disease Severity.” ID week. Philadelphia, PA October 2014.

Katherine Moyer, Impact of Preoperative Respiratory Viral Screening in Children Undergoing Cardiac Surgery. 2015 Pediatric Academic Societies Annual Meeting, San Diego, April 25 – 28, 2015.

Saha D, Watson J, Feldkamp R, Thornton D, Cummings M, Barber T. Urine Culture Follow Up in the Urgent Care: A Stewardship Opportunity. Sixth Annual International Pediatric Antimicrobial Stewardship Conference. Kansas City, MO. June 2015 (Oral Presentation).

Watson JR, Schwaderer AL, Hains DS. Urine β-defensin 2 concentration increases during urinary tract infection. IDWeek 2014. Philadelphia, PA. October 2014 (Poster Presentation).

Watson JR, Hains DS, Cohen DM, Schwaderer AL. Urine Antimicrobial Peptides: Novel Biomarkers to Improve Urinary Tract Infection Diagnosis. 2015 Pediatric Academic Societies Meeting. San Diego, CA. April 2015 (Oral Platform Presentation).

Christopher Ouellette, Andrea Ronchi, MD, Asuncion Mejias, MD, PhD, Susana Chavez-Bueno, MD, Douglas Salamon, MB(ASCP)SV, Lorenza Pugni, Fabio Mosca and Pablo J Sánchez, MD. Detection of Cytomegalovirus (CMV) in Cerebrospinal Fluid of Infants with Congenital CMV Infection: Is It Worth Doing the Lumbar Puncture? ID week. Philadelphia, PA October 2014.

Christopher Ouellette, MD, Preeti Jaggi, MD. Bartonella henselae Infective Endocarditis in Children: 2 Cases and Review of the Literature. 2015 Pediatric Academic Societies Meeting. San Diego, CA. April 2015

Eunkyung Song. Comparison of the FILMARRAY RESPIRATORY PANEL v1.7 and Human Adenovirus (HAdV) Specific Laboratory-Developed RT-PCR for Detection of HAdV in Pediatric Nasopharyngeal Samples. Daytona, FL. April 2015

Eunkyung Song. Detection of Human Adenovirus in Blood Is Associated with Higher Viral Load in Pediatric HAdV Respiratory Samples. IDWeek 2014. Philadelphia, PA. October 2014

Claudia Vicetti Miguel, Pablo Sánchez, Octavio Ramilo, Monica Ardura and Asuncion Mejias. Cytomegalovirus Meningitis: A Rare Complication of Severe Combined Immunodeficiency. St. Judes/PIDS Conference, Memphis, TN. Feb 20-21, 2014.

Antonara S, Wang H, Salamon D, Ouellette CP, Kahwash S, Leber A. Cat Got your Lymph Node? Verification and Clinical Application of a Laboratory Developed Test for the Diagnosis of Bartonella henselae in Pediatric Patients. ASM Conference 2015, New Orleans LA.

2014-2015 Presentations

Huanyu Wang, Doug Salamon, Stella Antonara, Cindy Burch, Claudia Vicetti Miguel and Amy Leber. Verification and Clinical Application of a Laboratory Developed Real Time PCR Assay for the Detection of Kingella kingae in Pediatric Patients. ASM Conference. New Orleans, LA. May 30 - June 2, 2015.

Eunkyung Song. Human Adenovirus (HAdV): acute HAdV disease vs. Incidental shedding. Nationwide Children’s Hospital Infectious Disease Research Consortium, 2014 (Oral presentation)

Eunkyung Song. Human Adenovirus (HAdV): acute HAdV disease vs. Incidental shedding. The Research Institute at Nationwide Children’s Hospital, Columbus, OH, 2014

Joshua Watson. 2015 “Pediatric Urinary Tract Infections: A Translational Approach to Address Clinical Challenges” Nephrology Urology Research Affinity Group. The Research Institute at Nationwide Children’s Hospital, Columbus, OH

Joshua Watson. 2015 Pediatric Urinary Tract Infections: A Translational Approach to Address Clinical Challenges” Infectious Diseases Consortium. Nationwide Children's Hospital, Columbus, OH

2014-2015 Publications

Spencer JD, Schwaderer AL, Becknell B, Watson J, Hains DS. The innate immune response during urinary tract infection and pyelonephritis. Pediatr Nephrol. 2014 Jul;29(7):1139-49. PMID: 23732397

Watson J and Mejias A. Human Herpesvirus-6 and Human Herpesvirus-7. In: McInerny T, ed. AAP Textbook of Pediatric Care. 2nd ed. (Publication pending)

2014-2015 Awards & Grants

201213 Watson (PI)        10/1/2013-9/30/2015
Intramural Grant, The Research Institute at Nationwide Children’s Hospital “A Novel Biomarker for Accurate UTI Diagnosis.” The goal of this study is to evaluate the antimicrobial peptide human α-defensin 5 as a diagnostic biomarker for urinary tract infections in children. Role: PI

20053814 Watson (PI)        7/1/2014-12/31/2014
Intramural Grant, Infectious Diseases Consortium, The Research Institute at Nationwide Children’s Hospital
“An Improved Biomarker for Pediatric Urinary Tract Infection” The goal of this study is to evaluate the antimicrobial peptide human neutrophil peptide 1-3 as a diagnostic biomarker for urinary tract infections in children. Role: PI

20054914 Christopher Ouellette MD (PI)        10/01/2014 - 09/30/2016
Intramural Grant, The Research Institute at Nationwide Children’s Hospital. Pablo J. Sanchez, MD, Asuncion Mejias MD, PhD. Whole Genome Expression Profiles in Infants with Congenital Cytomegalovirus Infection

Joshua Watson, 2015 Pediatric Academic Societies Young Investigator Travel Award
2015 Pediatric Academic Societies Meeting, San Diego, CA

IDSA Travel Grant: Eunkyung Song, Joshua Watson, Christopher Ouellette & Katherine Moyer

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Abstracts

Pietropaolo D, Magee M, Kao C, Knieper R, Mack K, Salamon D, Barson W, Ramilo O. “Non-CSF PCR Testing for Enterovirus in the Evaluation of Infants with Suspected Sepsis” [Abstract 1149]. Poster to be presented at the 2012 IDWeek Meeting, San Diego, CA, October 19, 2012.

Pietropaolo D, Magee M, Kao C, Mack K, Salamon D, Barson W, Ramilo O. “Should all young febrile infants 60 days of age or younger be tested for enterovirus in CSF with PCR?” [Abstract 69]. Poster presented at Pediatric Hospital Medicine 2012, Covington, KY, July 20, 2012.

Elizabeth J. Lucas, Birong Li, Sheryl Justice “Targeted Replacement of Uropathogens with Probiotic Nissle 1917.” NIAID/IDSA Infectious Diseases Research Careers Meeting. June 7, 2013 (Poster Presentation)

Elizabeth J. Lucas, Birong Li, Sheryl Justice “Targeted Replacement of Uropathogens with Probiotic Nissle 1917.” Clinical and Scientific Advances in Urinary Tract Infections, June 1, 2013 (Poster Presentation)

Cheryl Baxter, Chandra Singh, Ahmad Z. Mohamed, Elizabeth J. Lucas, Birong Li, Venkata R. Jayanthi, Sephen A Koff, Brian Vander-Brink, Sheryl S Justice. “Comparison of bacterial properties with hydrophilic catheters and PVC catheters of patients performing clean intermittent catheterization.” Clinical and Scientific Advances in Urinary Tract Infections. June 1, 2013 (Poster Presentation)

Elizabeth J. Lucas, Birong Li, Sheryl Justice “Targeted Replacement of Uropathogens with Probiotic Nissle 1917.” Physician Academic Societies Annual Meeting. May 5, 2013 (Poster Presentation)

Elizabeth J. Lucas, Birong Li, Sheryl Justice “Targeted Replacement of Uropathogens with Probiotic Nissle 1917.” 12th Annual Trainee Research Day Ohio State University. April 11, 2013 (Poster Presentation)

Elizabeth Lucas, “Targeted Pathogen Replacement with Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children.” Midwest Society of Pediatric Research, Inc. October 2012 (Platform Presentation)

Public Health Emergency Preparedness (PHEP) Epidemiologists’ Statewide Meeting. September 2012. Christine Zamastil, Kathy Mack. La Crosse Encephalitis Clinical Characteristics. Columbus, OH. (Oral Presentation)

Clinical Virology Symposium. April 2012. Kathy Mack, Kathy Everhart, Chris Bowersock, Christine Zamastil, Elizabeth Lucas, Katalin Koranyi, Amy Leber, and Mario J Marcon. Clinical Utility of Detection of IgG Antibodies by IFA to California Encephalitis Group Viruses in a Pediatric Hospital.

ID Week. October 2012. Christine Zamastil, Octavio Ramilo, Mario Marcon, Douglas Salamon, Rebecca Wallihan, Kathy Everhart. Clinical characteristics of children hospitalized with Mycoplasma pneumoniae (Mp) lower respiratory tract infection (LRTI) during a 2011 community outbreak in central Ohio. San Diego, California.

Pediatric Academic Society Conference. May 2013. Christine Zamastil, Octavio Ramilo, Douglas Salamon, Kathy Everhart, Mario Marcon. Severity of disease and co-morbidities during an outbreak of Mycoplasma pneumoniae in Central Ohio. Washington, DC.

Eunkyung Song, Co-Author: P. Jaggi. Can human Adenovirus viral loads distinguish acute HAdV infections from incidental shedding? IDSA, 2013 (Poster presentation)

Presentations

Pietropaolo D, Magee M, Kao C, Knieper R, Mack K, Salamon D, Barson W, Ramilo O. “Should all young febrile infants 60 days of age or younger be tested for enterovirus in CSF with PCR?” [Publication 4350.3]. Podium presentation at The Pediatric Academic Societies Annual Meeting, Boston, MA, May 1, 2012.

Invited panel member, Elizabeth Lucas, Alan Yates Distinguished Research Scholars Panel 12th Annual Trainee Research Day Ohio State University. April 11, 2013

Work in Progress: “Targeted Pathogen Replacement with Novel Probiotic Treatment of Prevention of Recurrent UTIs in Children” Combined Center for Microbial Pathogenesis and Section of Infectious Diseases. December 2012, Elizabeth Lucas

Publications

Eunkyung Song, Preeti Jaggi, and Amy Leber. Positive Human Adenovirus Testing from the Nasopharynx: Type and Viral Burden Aid in Discrimination between true disease and incidental detection. (soon to be submitted)

Awards & Grants

Thrasher Young Investigator Award, Elizabeth Lucas (PI) 6/1/2012-5/31/2014 Targeted pathogen replacement with novel probiotic treatment for prevention of recurrent UTIs in children The purpose of this study is to determine the efficacy of Nissle 1917 against multiple known uropathogens and the effect of probiotic treatment on the intestinal microbiota.

Elizabeth Lucas Co-principle investigator for an Investigational New Drug application with the FDA (IND#14997). “Phase 1 open label trial of Nissle 1917 to assess safety and tolerance in healthy adult volunteers”

April 2012 – 2012 NCH Research Poster Competition – Finalist, Domenico Pietropaolo

ID Week 2012 Travel Grant: Elizabeth Lucas, Christine Zamastil, Domenico Pietropaolo

 


 



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Abstracts

Elizabeth J. Lucas, Jennifer L Edwards. “Insights into Meningococcal Diseases” BOSS Seminar. March 2013 (Platform presentation)

Elizabeth J. Lucas, Cheryl Baxter. “Effect of catheter type on the microbiological milieu of patients with neurogenic bladder” NURAG consortium. December 2013 (Platform Presentation)

Elizabeth J. Lucas. “Urinary Tract Infections: An ID primer for ED physicians” Pediatric Emergency Dept Fellows Education. November 2013 (Platform Presentation)

Cheryl Baxter, Chandra Singh, Ahmad Z. Mohamed, Elizabeth J. Lucas, Birong Li, Venkata R. Jayanthi, Sephen A Koff, Brian VanderBrink, Sheryl S Justice. “Comparison of bacterial properties with hydrophilic catheters and PVC catheters of patients performing clean intermittent catheterization.” Magnet Nursing Conference. October 2013 (Poster Presentation)

Elizabeth J Lucas, Cheryl Baxter, Chandra Singh, Ahmad A. Mohamed, Birong Li, Jingwen Zhang, Venkata R. Jayanthi, Stephen A. Koff, Brian VanderBrink, Sheryl S. Justice. “Changes in urinary microbiological milieu of neurogenic bladder patients with use of a hydrophilic catheter as compared to conventional PVC catheters.” The Research Institute at Nationwide Children’s Hospital Annual Retreat. October 2013 (Poster Presentation)

Elizabeth J. Lucas, Chole Hamrick Williams, Birong Li, Sheryl Justice “Targeted Replacement of Uropathogens with Probiotic Nissle 1917.” IDWeek. October 3, 2013 (Poster Presentation)

ID Week. October 2013. Christine Zamastil, Octavio Ramilo, Mario Marcon, Douglas Salamon, Kathy Everhart. Molecular melting curve analysis demonstrates that 9% of Mycoplasma pneumoniae strains in Central Ohio are macrolide resistant. San Francisco, CA. (Oral Presentation)

Pediatric Academic Society Conference. May 2014. Christine Zamastil, Octavio Ramilo, Douglas Salamon, Kathy Everhart, Mario Marcon. Macrolide-resistant (mac-R) Mycoplasma pneumoniae (Mp) strains are detected in Central Ohio and may not respond to macrolide therapy. Vancouver, BC. (Oral Presentation)

Watson J, Spencer JD, Cohen D, Sánchez P, Hains D. Outpatient management of presumed urinary tract infection in the Emergency Department – another challenge in antimicrobial stewardship. 2014 Pediatric Academic Societies and Asian Society for Pediatric Research joint Meeting. Vancouver, BC. May 2014 (Poster Presentation).

Eunkyung Song, Co-Author: P. Jaggi. Human Adenovirus (HAdV) Viral Loads May Help Differentiate Acute HAdV Infections From Incidental Shedding. 2014 Pediatric Academic Societies and Asian Society for Pediatric Research joint Meeting. Vancouver, BC. May 2014 (Poster Presentation).

Watson J, Easterling B, Spencer JD. Antimicrobial peptides: promising therapeutics against uropathogenic Escherichia coli. 2014 Pediatric Academic Societies and Asian Society for Pediatric Research joint Meeting. Vancouver, BC. May 2014 (Poster Presentation).

Eunkyung Song, Octavio Ramilo, Amy Leber, Douglas Salamon, Adriana Kajon, Preeti Jaggi. Human Adenovirus (HAdV) Viral Loads May Help Differentiate Acute HAdV Infections from Incidental Shedding. 2014 Pediatric Academic Societies and Asian Society for Pediatric Research joint Meeting. Vancouver, BC. May 2014 (Poster Presentation)

Elizabeth Lucas, Amy Leber, Octavio Ramilo. Broad –Range PCR Application in a Large Academic Pediatric Center: Clinical Value and Challenges. 2014 Pediatric Academic Societies and Asian Society for Pediatric Research joint Meeting. Vancouver, BC. May 2014

Presentations

2013 “Urine Trouble: Burning Issues in the Innate Response to Urinary Tract Infections” Joshua Watson, Co-Presenter, Bench to Outcomes Seminar Series The Research Institute at Nationwide Children’s Hospital Columbus, OH

2014 “Diagnosis & Management of UTI in Infants” Joshua Watson. Pediatric Emergency Medicine Fellowship Lecture Series. Nationwide Children’s Hospital, Columbus, Ohio


Publications

Chandra Singh, Cheryl Baxter, Ahmad Z. Mohamed, Elizabeth J Lucas, Birong Li, Jingwen Zhang, Venkata R. Jayanthi, Stephen A. Koff, Brian VanderBrink, Sheryl S. Justice. “Changes in urinary microbiological milieu of neurogenic bladder patients with use of a hydrophilic catheter as compared to conentional PVC catheteters.”

Spencer JD, Schwaderer AL, Becknell B, Watson J, Hains DS. The innate immune response during urinary tract infection and pyelonephritis. Pediatr Nephrol. 2013 Jun 5. [Epub ahead of print] PMID: 23732397

Awards & Grants

201213 Watson (PI) 10/1/2013-9/30/2015
Intramural Grant, The Research Institute at Nationwide Children’s Hospital “A Novel Biomarker for Accurate UTI Diagnosis.” The goal of this study is to evaluate the antimicrobial peptide human α-defensin 5 as a diagnostic biomarker for urinary tract infections in children. Role: PI

Internal Grant PI: Preeti Jaggi Co-Investigator, Eunkyung Song                                                         August 2013 – April 2015
Title: Identifying comprehensive virologic characteristics of HAdV to discriminate true disease from latent infection.
Study Goal: To improve the clinical interpretation of molecular based detection of HAdV in various states of health utilizing comprehensive virologic characterizations including viral cultures, typing, blood PCR and microarray.

“Posters in the Park” ID Week 2013, Elizabeth Lucas

ID Week 2013 Travel Grant: Elizabeth Lucas, Christine Zamastil, Eunkyung Song

Pediatric Infectious Disease Society Poster Award, October 2013, Elizabeth Lucas
 



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