PAJER LABORATORY
Dr. Pajer is a psychiatrist whose research focuses on biological aspects of female antisocial behavior. She is particularly interested in how the hypothalamic pituitary adrenal (HPA) axis portion of the stress response system is correlated with the behavior and physical health of this population. She is currently working on an NIMH-funded project to study HPA axis function in detail in adolescent antisocial girls. This study also examines whether PHA axis function predicts long-term severity and persistence of antisocial behavior in girls. Dr. Pajer is also a co-investigator on a NIDA-funded study that is assessing HPA axis function in neglected and abused offspring of substance-abusing fathers and is a co-investigator on a NIDA- funded study to improve service delivery for adolescent substance abuse problems. Work in progress for funding includes studying the stress response system of women with various types of psychopathology during pregnancy and examining their mothering behaviors after delivery. |
| Projects |
HPA Axis Function in Adolescent Antisocial Females
This study investigates the basal and reactive functions of the HPA axis in antisocial adolescent girls, compared to psychiatric and normal controls. 180 girls will be examined and then followed for a year to determine if HPA axis abnormalities are associated with the severity or persistence of antisocial symptoms.
Project: R01-MH066003-01 (Kathleen Pajer, M.D., MPH)
Funding period:04/01/03-03/31/08
Funding agency:NIMH
Collaborating Investigator(s):
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Impact of Child Neglect in Substance Abuse Families
This project investigates neglect as the outcome of both parent and child characteristics it enables prospectively tracking intraindividual factors in familial context that increase and decrease the risk for neglect and subsequent outcomes.
Project: DE13844 (A. Mezzich)
Funding period: 07/01-08/30/05
Funding agency: NIDCR & NIDA
Role: Co-Investigator
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Trial of Automated Risk Appraisal and Adolescents
The goal of this study is to improve servies for problem drug use and abuse and other related health risking behaviors for youth in primary care settings through research on early identification and monitoring.
Project: DA018943-01 (K. Kelleher)
Funding period:10/01/04-09/30/08
Funding agency: NIDA
Role: Co-Investigator
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The Spatio-temporal diffusion of Psychotropic Medications to Rural Children
Major goal of this project is to develop interventions that accelerate the adoption of evidence-based practices in rural areas and thereby reduce the burden of mental illness on rural children.
Project: (R. Penrod)
Funding period: 07/01/06 - 06/30/08
Funding agency: NIMH
Role: Co-Investigator
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Pediatric PROMIS: Advancing the Measurement and Conceptualization of Child Health
Pediatric PROMIS network is intended to be a resource for the clinical research community. The aims of the study are to 1) develop and test a large bank of items measuring patient-reported outcomes (PROS) 2) create a computerized adaptive testing (CAT) system that would allow for efficient, psychometrically robust assessment of PROs in clinical research involving a wide range of chronic diseases and 3) create a publicly available system that could be added to and modified periodically and that would allow researchers to access a common repository of items and CAT system.
Project: 1U01AR057956-01 (Gardner)
Funding period: 09/30/2009-07/31/2010
Funding agency: Children's Hospital of Philadelphia |
Psychoneuroimmune contributions to postpartum depression
This Funding Opportunity Announcement (FOA) solicits research project grant applications on the topic of women's mental health in relation to pregnancy and the postpartum period. Stdies exploring the effects of current or lifetime drug abuse, including treatment status and comorbid conditions, on onset and course of mental disorders during the perinatal period are also encouraged.
Project: 7R01NR011278-02 (Kathleen Pajer, M.D., MPH)
Funding period: 07/01/2009-6/30/2013
Funding agency:University of Colorado Denver
Collaborating Investigator(s): |
Faculty and Staff
Principal Investigator: Kathleen Ann Pajer, M.D., M.P.H.
e-mail: Kathleen.Pajer@nationwidechildrens.org |
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Cochran, Justinn
e-mail: Justinn.Cochran@nationwidechildrens.org |
