Center for Biobehavioral Health

YEATES LABORATORY
Projects
Postconcussive Symptoms in Children with Mild Head Injuries

The major goals of this study are to examine the natural history, prediction, and consequences of post-concussive symptoms in children with mild closed-head injuries.

Project: R01-HD39834-0156 (Keith Yeates, Ph.D.)
Funding period:5/24/01-4/30/06
Funding agency:NICHD
Collaborating Investigator(s):

Child and Family Sequelae of Preschool Brain Injury

The major goal of this study is to prospectively examine recovery from traumatic brain injury in preschool children and their families.

Project: R01-HD42729-01 (S. Wade)
Funding period:9/10/02-8/31/07
Funding agency:NICHD
Collaborating Investigator(s): Keith Yeates, Ph.D.

Neurobehavioral Late-Effects in Pediatric Brain Tumors

The major goals of this study are to examine the effects of cranial radiation on brain development and neurobehavioral functioning in children with brain tumors.

Project: R01-CA112182-01 (M. D. Ris)
Funding period:3/22/05 - 2/28/10
Funding agency:NCI
Collaborating Investigator(s): Keith Yeates, Ph.D.

TOPS Intervention

The major goal of this study is to undertake an integrative, mulit-level study of the social outcomes of childhood traumatic brain injury.

Project: DOE#H133G050239-06                                                    Funding Period: 10/01/07-9/30/09                                                   Funding Agency: US Dept of Ed (Cinci)                                   Collaborating Investigators:

Teen Online Problem Solving for Adolescent Traumatic Brain Injury

The major goal of this study is to expand a randomized clinical trial examining the efficacy of an on-line problem-solving intervention for adolescents with traumatic brain injuries and their families.

Project:                                                                                                     Funding Period: 7/01/08-6/30/09                                                              Funding Agency: Ohio Department of Safety                                   Collaborating Investigators:

School Transition Reentry Program

Project:                                                                                                     Funding Period:                                                                                          Funding Agency:                                                                                       Collaborating Investigators:

Faculty and Staff
Principal Investigator: Keith Owen Yeates, Ph.D., ABPP/CN
  e-mail: Keith.Yeates@nationwidechildrens.org

 

Davis, Amy
  e-mail: Amy.Davis2@nationwidechildrens.org

 

Ginn, Melissa
  e-mail: Melissa.Ginn@nationwidechildrens.org

 

Hajek, Christine
  e-mail: Christine.Hajek@nationwidechildrens.org

 

Herren, Luke
  e-mail: Luke.Herren@NationwideChildrens.org

 

Mark, Erin
  e-mail: erin.mark@nationwidechildrens.org

 

Moran, Lisa
  e-mail: Lisa.Moran@NationwideChildrens.org

 

Smith, Kamma
  e-mail: Kamma.Smith@nationwidechildrens.org



GERHARDT LABORATORY
Cynthia A. Gerhardt, Ph.D. is an Associate Professor in the Department of Pediatrics and Psychology at The Ohio State University. Her research focuses on risk and resilience factors associated with family adjustment to bereavement and childhood chronic illnesses, such as cancer. In addition, she is currently involved in research that examines the impact of palliative care education, family communication, and health promotion interventions on the care and quality of life of families affected by childhood cancer.
Projects
Sibling and Parent Bereavement from Childhood Cancer

The goal of this multi-site project is to evaluate the psychosocial functioning of siblings and parents following the death of a child from cancer.
 
Project: R01-CA098217-01 (Cynthia Gerhardt, Ph.D.)
Funding period:8/01/05-07/31/10
Funding agency:NCI
Collaborating Investigator(s): Kathryn Vannatta, Ph.D.; Maru Barrera, Ph.D.; MaryJo Gilmer, Ph.D.; Bruce E. Compas, Ph.D.; Diane L. Fairclough, DrPH

Social Outcomes in Pediatric Traumatic Brain Injury
 
R01 HD048946 (Yeates, PI)
Funding period: 04/01/06-03/31/11
Funding agency: NIH/NICHD
Role: CI
Collaborating Investigators: Keith Yeates, Ph.D. ABPP/CN, Kathryn Vannatta, Ph.D., H. Gerry Taylor, Ph.D. ABPP/CN, Maureen Dennis, Erin Bigler.

Parent-Child Communication about Cancer

R01 CA 118332 (Compas, PI)
Funding period: 04/01/07 – 03/31/12
Funding agency: NIH/NCI
Role: Site PI
Collaborating Investigators: Bruce E. Compas, Ph.D; MaryJo Gilmer, PhD.; Tammi Young-Saleme, Ph.D.; Kathryn Vannatta, Ph.D.

Psychosocial Outcomes for Pediatric Brain Tumor Survivors
 
RSGPB PBP-309801 (Vannatta, PI)
Funding period: 07/01/03-06/30/08
Funding agency: American Cancer Society, National Office
Role: Site-PI
Collaborating Investigators: Kathryn Vannatta, Ph.D.; Andrea Farkas-Patenaude, Ph.D.; Maru Barrera, Ph.D.; MaryJo Krupst, Ph.D; Diane L. Fairclough, DrPH

Development of Palliative Care Education for Pediatric Oncologists
 
HSK 345703 (Klopfenstein, PI)
Funding period: 07/01/04-06/30/07
Funding agency: Hope Street Kids
Role: CI

Faculty and Staff
Principal Investigator: Cynthia A. Gerhardt, Ph.D.
  e-mail: Cynthia.Gerhardt@NationwideChildrens.org

 

Ach, Emily
  e-mail: emily.ach@nationwidechildrens.org

 

Corbisiero, Amii
  e-mail: Amii.Corbisiero@nationwidechildrens.org

 

Davis, Amy
  e-mail: Amy.Davis2@nationwidechildrens.org

 

Grossenbacher, Julie
  e-mail: julie.grossenbacher@nationwidechildrens.org

 

Kaal, Julia
  e-mail: Julia.Kaal@nationwidechildrens.org

 

Salley, Chrissy
  e-mail: Chrissy.Salley@nationwidechildrens.org

 

Smith, Kamma
  e-mail: Kamma.Smith@nationwidechildrens.org



LEMANEK LABORATORY

The Lemanek lab is staffed by Kathleen Lemanek, Ph.D. (Principal Investigator), Andrea King, Psy.D. (Fellow/Research Coordinator), and Emily Clough-Paabo, B.A. (Research Assistant). Our lab is currently engaged in a NIH-funded R01 study. This is a multisite randomized clinical trial investigating the effects of a behavioral meal time intervention on nutritional intake and weight status of preschoolers with cystic fibrosis. Our lab is also involved in other studies in both cystic fibrosis and sickle cell disease. We engage in clinical research that focuses on the psychosocial aspects of living with a chronic illness as well as adherence to complex treatment regimens.

Projects

Faculty and Staff
Principal Investigator: Kathleen L. Lemanek, Ph.D.
  e-mail: Kathleen.Lemanek@nationwidechildrens.org

 

Clough-Paabo, Emily
  e-mail: Emily.Clough-Paabo@nationwidechildrens.org

 

Davis, Amy
  e-mail: Amy.Davis2@nationwidechildrens.org

 

King, Andrea
  e-mail: Andrea.King@nationwidechildrens.org

 

Richdale-Robb, June
  e-mail: June.RichdaleRobb@nationwidechildrens.org

 

Smith, Kamma
  e-mail: Kamma.Smith@nationwidechildrens.org



MACKNER LABORATORY
My primary research is in the area of adolescent adjustment to chronic illness and the interaction of biopsychosocial factors that contribute to optimal adjustment, particularly in adolescents with gastrointestinal disorders such as inflammatory bowel disease (IBD). My current work is examining biopsychosocial issues in adolescents with IBD and relationships between inflammation and emotional functioning in pediatric IBD. I am also collaborating with Wallace Crandall, M.D., on his project investigating psychosocial stress and genetic moderators in youth with IBD, as well as John Campo, M.D., on his project that is investigating treatment for abdominal pain.
Projects

Social Functioning in Adolescent Chronic Illness

This project is investigating social functioning in adolescents with IBD and identifying biopsychosocial pathways between chronic illness and its impact on adolescent social functioning. Despite the importance and complexity of adolescents' social world, little is known about the effect of a chronic illness on adolescent social functioning.

Project: 1R01HD058317-01A2                                                                   Funding Period: 4/10/2008 - 3/31/2013                                                 Funding Agency: NICHD- National Institute of Child Health and Human Development                                                                                              Collaborating Investigators: Wallace Crandall M.D., Bill Gardner Ph.D., Kathryn Vannatta, Ph.D.

Inflammation and Depression in Pediatric Gastrointestinal Disorders

This study is investigating the role in the development of depression in children with IBD. Aspects of the inflammatory process (e.g., cytokines, hypothalamic-pituitary-adrenal axis function) may place these children at increased risk for depression symptoms.

Project:                                                                                                        Funding Period: 2/1/2008-12/31/2009                                                       Funding Agency: Broad Foundation & Wolfe Foundation                         Collaborating Investigators: John Campo M.D., Wallace Crandall M.D., Kim McBride M.D., Kathleen Pajer, M.D.

Brief CBT for Pediatric Abdominal Pain & Anxiety

This study is evaluating a brief cognitive behavioral therapy protocol for youth with functional abdominal pain and clinically significant anxiety symptoms.

Project: R34 MH073769                                                                        Funding Period: 11/21/2006 - 11/21/2009                                             Funding Agency: NIMH                                                                        Collaborating Investigators: John Campo M.D. (PI), Carlo DiLorenzo M.D., Robin Weersing Ph.D. 

Faculty and Staff
Principal Investigator: Laura M. Mackner, Ph.D.
  e-mail: Laura.Mackner@nationwidechildrens.org

 

Bickmeier, Bob
  e-mail: bob.bickmeier@nationwidechildrens.org

 

Clough-Paabo, Emily
  e-mail: Emily.Clough-Paabo@nationwidechildrens.org

 

Davis, Amy
  e-mail: Amy.Davis2@nationwidechildrens.org

 

Harvey, Carolyn
  e-mail: Carolyn.Harvey@nationwidechildrens.org

 

Ross, Christina
  e-mail: Christina.Ross2@NationwideChildrens.org

 

Smith, Kamma
  e-mail: Kamma.Smith@nationwidechildrens.org

 

Szarka, Stefanie
  e-mail: Stefanie.Szarka@nationwidechildrens.org



PAJER LABORATORY
Dr. Pajer is a psychiatrist whose research focuses on biological aspects of female antisocial behavior. She is particularly interested in how the hypothalamic pituitary adrenal (HPA) axis portion of the stress response system is correlated with the behavior and physical health of this population. She is currently working on an NIMH-funded project to study HPA axis function in detail in adolescent antisocial girls. This study also examines whether PHA axis function predicts long-term severity and persistence of antisocial behavior in girls. Dr. Pajer is also a co-investigator on a NIDA-funded study that is assessing HPA axis function in neglected and abused offspring of substance-abusing fathers and is a co-investigator on a NIDA- funded study to improve service delivery for adolescent substance abuse problems. Work in progress for funding includes studying the stress response system of women with various types of psychopathology during pregnancy and examining their mothering behaviors after delivery.
Projects
HPA Axis Function in Adolescent Antisocial Females

This study investigates the basal and reactive functions of the HPA axis in antisocial adolescent girls, compared to psychiatric and normal controls. 180 girls will be examined and then followed for a year to determine if HPA axis abnormalities are associated with the severity or persistence of antisocial symptoms.

Project: R01-MH066003-01 (Kathleen Pajer, M.D., MPH)
Funding period:04/01/03-03/31/08
Funding agency:NIMH
Collaborating Investigator(s):

Impact of Child Neglect in Substance Abuse Families

This project investigates neglect as the outcome of both parent and child characteristics it enables prospectively tracking intraindividual factors in familial context that increase and decrease the risk for neglect and subsequent outcomes.

Project: DE13844 (A. Mezzich)
Funding period: 07/01-08/30/05
Funding agency: NIDCR & NIDA
Role: Co-Investigator

Trial of Automated Risk Appraisal and Adolescents

The goal of this study is to improve servies for problem drug use and abuse and other related health risking behaviors for youth in primary care settings through research on early identification and monitoring. 

Project: DA018943-01 (K. Kelleher)
Funding period:10/01/04-09/30/08
Funding agency: NIDA
Role: Co-Investigator

The Spatio-temporal diffusion of Psychotropic Medications to Rural Children

Major goal of this project is to develop interventions that accelerate the adoption of evidence-based practices in rural areas and thereby reduce the burden of mental illness on rural children.

Project:   (R. Penrod)
Funding period: 07/01/06 - 06/30/08
Funding agency: NIMH
Role: Co-Investigator

Faculty and Staff
Principal Investigator: Kathleen Ann Pajer, M.D., M.P.H.
  e-mail: Kathleen.Pajer@nationwidechildrens.org

 

Davis, Amy
  e-mail: Amy.Davis2@nationwidechildrens.org

 

Leininger, Lisa
  e-mail: Lisa.Leininger@nationwidechildrens.org

 

Lourie, Andrea
  e-mail: Andrea.Lourie@nationwidechildrens.org

 

Smith, Kamma
  e-mail: Kamma.Smith@nationwidechildrens.org



REYNOLDS LABORATORY
Dr. Reynolds is a developmental psychologist with research interests in the assessment of different dimensions of impulsive behavior, primarily through the use of laboratory behavioral tasks, and how impulsive behavior is related to cigarette-smoking uptake and cessation among adolescents. His interests also include the development and evaluation of contingency management smoking-cessation programs oriented to adolescent populations.
Projects

Impulsive Behavior and Treatment Outcomes for  Adolescent Smoking

PROJECT: R01 DA023087-01A2
FUNDING PERIOD: 07/01/08 - 6/30/13
FUNDING AGENCY: NIH/NIDA
ROLE: PI                               

The primary goal of this research is to assess the relationships between different dimensions of impulsive behavior and treatment response for adolescents participating in a widely prescribed, social-cognitive type  treatment program for smoking.

 

A Web-Based Intervention with Adolescent Smokers of Appalachian Ohio

PROJECT: 1RC1CA144744-01
FUNDING PERIOD: 09/30/09 - 09/29/11
FUNDING AGENCY: NIH/NCI
ROLE: PI

A web-based contingency management program for cigarette smoking will be evaluated that utilizes an Internet server and video recordings of smoking-status verifications as an effective way to reach rural adolescents. Also, different dimensions of impulsive behavior will be explored as predictors of treatment response. 

 

Web-Based Contingency Management for Smoking Abstinence with Adolescents

PROJECT: R01 DA023476-01A2
FUNDING PERIOD: 03/01/10 - 2/28/15
FUNDING AGENCY: NIH/NIDA
ROLE: PI

In response to the need for treatments appropriate for adolescent smokers, this research (utilizing a two-group randomized-control design, n = 63 per group) will evaluate the effectiveness and efficacy of a new and innovative Internet-based contingency-management (CM) program for smoking abstinence with adolescent smokers.

Faculty and Staff
Principal Investigator: Brady Reynolds, Ph.D.
  e-mail: Brady.Reynolds@nationwidechildrens.org

 

Brennan, Cody
  e-mail: cody.brennan@nationwidechildrens.org

 

Davis, Ashley
  e-mail: ashley.davis@nationwidechildrens.org

 

Fields, Sherecce
  e-mail: Sherecce.Fields@nationwidechildrens.org

 

Huynh, Lynn
  e-mail: Lynn.Huynh@nationwidechildrens.org

 

Patak, Michele
  e-mail: Michele.Patak@nationwidechildrens.org

 

Riley, Christine
  e-mail: Christine.Riley@nationwidechildrens.org

 

Sabet, Mae
  e-mail: mae.sabet@nationwidechildrens.org

 

Tingler, Laura
  e-mail: laura.tingler@nationwidechildrens.org

 

Wallace, Bryan
  e-mail: bryan.wallace@nationwidechildrens.org

 

Weiser, Daniel
  e-mail: Daniel.Weiser@nationwidechildrens.org

 

Whitt, Melissa
  e-mail: Melissa.Whitt@nationwidechildrens.org



VANNATTA LABORATORY
Kathryn Vannatta, Ph.D., is an Associate Professor in the Departments of Pediatrics and Psychology at The Ohio State University. Dr. Vannatta completed her graduate work at the University of Oregon, a pre-doctoral internship at Duke University Medical Center, and a post-doctoral fellowship at Cincinnati Children's Hospital Medical Center. She has a history of funded research in pediatric psychology emphasizing social, emotional and behavioral outcomes of children affected by cancer and its treatment. Dr. Vannatta is broadly interested in childhood family and peer relations and how risk and resilience are demonstrated in social development when children are faced with severe chronic illness or significant disruption in family functioning. These interests have led Dr. Vannatta to conduct research on the psychosocial and family outcomes experienced by children with a variety of chronic illnesses, children who have undergone stem cell transplantation, and children with a family member affected by a severe or life threatening disease (e.g. maternal breast cancer). Her collaborators on these projects include colleagues in Columbus as well as at Children's Hospital of Philadelphia, Cincinnati Children's Hospital Medical Center, Dana Farber Cancer Institute, MD Anderson Cancer Center, Medical College of Wisconsin, St. Jude's Research Hospital, The Hospital for Sick Kids in Toronto, University of Colorado Health Sciences Center. Dr. Vannatta has provided clinical, research, and professional mentorship to graduate students, pre-doctoral interns, and post-doctoral fellows in pediatric psychology.
Projects

Psychosocial Impact of Pediatric Brain Tumors

This research is identifying school-aged children who have completed treatment for primary CNS tumors at four pediatric oncology centers.  Indentical data will be obtained for these children and comparison classmates from multiple sources in classroom (teacher, peer, self-report) and homes (mother, father, and child-report) to allow tests of group differences in social, emotional, behavioral, and parent/family functioning. In addition to testing group differences, analyses will test models about the mechanisms that mediate differences in outcomes, including medical late effects, child attributes, and soical information processing skills.  This work is designed to aid efforts to design clinical trials to prevent or ameliorate long-term psychosocial morbidity in BT survivors.

Project: RSGPB-03-098-01-PBP (Kathryn Vannatta, Ph.D.)
Funding period:07/01/03-6/30/08
Funding agency: American Cancer Society
Collaborating Investigator(s):  Dr. Cynthia Gerhardt & Dr. Randy Olshefski in Columbus as well as co-investigators at Dana Farber Cancer Institute, Medical College of Wisconsin, the Hospital for Sick Kids in Toronto, and the University of Colorado Health Science Center.

 

Neurobehavioral Late-Effects in Pediatric Brain Tumors

The overall goal of the proposal is to investigate whole brain and regional IBED in predicting brain and neurobehavioral late-effects of radiation therapy.  Advanced imaging (volumetrics, spectroscopy, diffusion imaging) and neuropsychological measurement strategies will be utilized in a two-center, prospective longitudinal design.

Project: R01-CA112182 (Co-Investigator)
Funding period:04/01/05-3/31/10
Funding agency: National Cancer Institute
Collaborating Investigator(s):  This investigation is a collaboration with Dr. Doug Ris who is the overall PI for the study at Cincinnati Children's Hospital Medical Center.  Dr. Keith Yeates is the site PI in Columbus. 

 

Sibling and Parent Bereavement from Childhood Cancer

This investigation is a multi-site study of families who have recently experienced child bereavement following treatment for cancer using a controlled, short term (12-18 month) longitudinal design.

Project: R01 CA098217
Funding period:07/01/05-6/30/10
Funding agency: National Cancer Institute
Collaborating Investigator(s): Dr. Cynthia Gerhardt is the overall PI for the study which is a collaboration with investigators at The Hospital for Sick Kids in Toronto, University of Colorado Health Sciences Center and Vanderbilt University.

 

Social Outcomes in Pediatric Traumatic Brain Injury

The major goal of this study is to undertake an integrative, multi-level study of the social outcomes of childhood traumatic brain injury.

Project:  R01 HD048946
Funding period:08/01/06-03/31/11
Funding agency: National Institute of Child Health and Human Development
Collaborating Investigator(s):  Dr. Keith Yeates is the overall PI for the study which is a collaboration with investigators at the Cleveland Clinic, The Hospital for Sick Children in Toronto and the University of Maryland.

 

 

Parent-Child Communication about Cancer

The objective of this study is to describe the content and process of communication about a child's cancer diagnosis and treatment using direct observations of parents and children as well as traditional self report measures. Longitudinal questionnaire assessments will also evaluate the association of communication and outcomes for children and their families.

Project: R01 CA118332-01
Funding period:07/01/07-6/30/12
Funding agency: National Cancer Institute
Collaborating Investigator(s): This investigation is a collaboration with Dr. Bruce Compas at Vanderbilt University.  Dr. Cynthia Gerhardt is the site PI in Columbus.

 

Faculty and Staff
Principal Investigator: Kathryn Vannatta, Ph.D.
  e-mail: Kathryn.Vannatta@nationwidechildrens.org

 

Ach, Emily
  e-mail: emily.ach@nationwidechildrens.org

 

Acker, Jenna
  e-mail: Jennifer.Acker@nationwidechildrens.org

 

Davis, Amy
  e-mail: Amy.Davis2@nationwidechildrens.org

 

Grossenbacher, Julie
  e-mail: julie.grossenbacher@nationwidechildrens.org

 

Kaal, Julia
  e-mail: Julia.Kaal@nationwidechildrens.org

 

Salley, Chrissy
  e-mail: Chrissy.Salley@nationwidechildrens.org

 

Smith, Kamma
  e-mail: Kamma.Smith@nationwidechildrens.org