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|
| Education |
| 2008 |
|
Fellowship |
|
Pediatric Infectious Diseases |
|
Nationwide Children's Hospital, Columbus, OH |
| 2004 |
|
Residency |
|
Internal Medicine/Pediatrics |
|
The Ohio State University, Nationwide Children's Hospital, Columbus, OH |
| 2000 |
|
MD |
|
Medicine |
|
Indiana University School of Medicine, Indianapolis, IN |
| 1995 |
|
BS |
|
Chemistry |
|
Purdue University School of Science, West Lafayette, IN |
| Professional Experience |
| 2008- PRES |
Investigator, Center for Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital |
| 2008- PRES |
Assistant Professor, Department of Pediatrics, Division of Pediatric Infectious Diseases, The Ohio State University College of Medicine and Nationwide Children's Hospital |
| 2004- 2005 |
Internal Medicine-Pediatrics Practice, Columbus Neighborhood Health Centers, Columbus, OH. |
Research Interests
Dr. Honegger’s research is focused on understanding the role of T-cell immunity in the vertical transmission of the hepatitis C virus (HCV). Vertical transmission (passage from mother to child during pregnancy or birth) of HCV occurs in approximately 5% of pregnancies to HCV infected mothers and is now the leading route of infection in children. Although T-cell immunity is known to be critical for control of acute infection in adults and animal models of HCV, the roles of maternal and infant T-cell responses in preventing vertical transmission and reasons for their failure remain unknown. To address these issues Dr. Honegger is studying ex-vivo T-cell responses to HCV antigens in a cohort of HCV-infected pregnant women and their subsequent infants.
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| Selected Publications |
| Honegger JR, Brady MT. Viral Respiratory Infections. In Rudolph's Pediatrics. 22nd ed. Edited by Rudolph AM, Hoffman JIE, Rudolph CD. Stamford, CN: Appleton & Lange. (In press) |
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