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MUNSON LABORATORY
Nontypeable Haemophilus influenzae (NTHi) is an important cause of otitis media in children, and a major cause of lower respiratory disease in children in the developing world. The organism is also associated with exacerbations of chronic bronchitis, and pneumonia in elderly and immunocompromised patients.
Haemophilus ducreyi is the causative agent of chancroid, a sexually transmitted disease. Chancroid ulcers facilitate the transmission of HIV.
My laboratory is employing a number of genetic and immunological approaches in order to assess the role of outer membrane proteins, toxins and adhesins in the pathogenesis of Haemophilus disease.
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| Education |
| 1980 |
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Fellow |
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Biochemistry |
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Washington University School of Medicine, St. Louis, MO |
| 1976 |
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Ph.D. |
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Microbiology |
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University of Connecticut School of Medicine, Farmington, CT |
| 1968 |
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B.A. |
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Bacteriology |
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University of Connecticut, Storrs, CT |
| Professional Experience |
| 1999- PRES |
Professor of Microbiology. The Ohio State University. |
| 1997- PRES |
Director, Core DNA Sequencing Facility, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio. |
| 1994- PRES |
Professor of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, College of Medicine |
| 1994- PRES |
Professor of Pediatrics, The Ohio State University, School of Medicine |
| 1989- 1994 |
Associate Professor of Molecular Microbiology, Washington University, School of Medicine |
| 1989- 1994 |
Associate Professor of Pediatrics, Washington University, School of Medicine |
| 1987- 1988 |
Assistant Professor of Molecular Microbiology, Washington University, School of Medicine |
| 1982- 1988 |
Assistant Professor of Pediatrics, Washington University, School of Medicine |
| 1980- 1982 |
Research Assistant Professor of Pediatrics, Washington University, School of Medicine, St. Louis, MO. |
MUNSON LABORATORY STAFF
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Principal Investigator:
Robert S. Munson, Jr., Ph.D.
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| Selected Publications |
Post DM, Munson RS Jr., Baker BD, Zhong H, Bozue JA, and Gibson BW. "Identification of genes involved in the expression of atypical lipooligosaccharide structures from a second class Haemophilus ducreyi, Infect. Immun 2007; 75(1):113-21. |
| Harrison A, Ray WC, Baker BD, Armbruster DW, Bakaletz LO and Munson RS Jr. "The OxyR regulon in nontypeable Haemophilus influenze", J Bacteriol 2007; 189(3):1004-12. |
| Harrison A, Dyer DW, Gillaspy A, Ray WC, Mungur R, Carson MB, Zhong H, Gipson J, Gipson M, Johnson LS, Lewis L, Bakaletz LO and Munson RS Jr. "Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: Comparative study with H. influenzae serotype d, strain KW20", J Bacteriol 2005; 187(13):4627-36. |
| Johnston JW, Zaleski A, Allen S, Mootz JM, Armbruster D, Gibson BW, Apicella MA, and Munson RS Jr. "Regulation of sialic acid transport and catabolism in Haemophilus influenzae", Molecular Microbiology 2007; 66(1):26-39. |
Bakaletz LO, Baker BD, Jurcisek JA, Harrison A, Novotny LA, Bookwalter JE, Mungur R and Munson RS Jr,. “Demonstration of type IV pilus expression and a twitching phenotype by Haemophilus influenzae”, Infect Immun 2005; 73(3):1635-43. |
Post DM, Mungur R, Gibson BW and Munson RS Jr., "Identification of a novel sialic acid transporter in Haemophilus ducreyi", Infect Immun. 2005; 73(10):6727-35.
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