The Research Institute at Nationwide Children's Hospital - Federica Montanaro, Ph.D. Profile
Federica Montanaro, Ph.D.
photo of Federica Montanaro, Ph.D.
Center for Gene Therapy

PRINCIPAL INVESTIGATOR

Federica.Montanaro@
nationwidechildrens.org


The Research Institute at Nationwide Children's Hospital
700 Childrens Drive, WA 3020
Columbus, OH 43205
p: 614.355.3571 | f: 614.355.5247

MONTANARO LABORATORY
My laboratory is interested in muscle regeneration and in the development of cell-based therapies for muscular dystrophy disorders, in particular Duchenne Muscular Dystrophy. On one hand, we are studying in vitro models of muscle regeneration to identify genes and pathways that are important for the activation of muscle stem cells and their participation in muscle repair. We are using a combination of gene expression arrays and RNA interference to identify and characterize genes of interest. On the other hand, we have identified stem cells from the adult skin that are able to participate in muscle repair following vascular delivery. We are now optimizing the transplantation parameters and further characterizing these cells to improve the efficiency with which they repair dystrophic muscles.