Garg Lab Publications

1.  *Yamagishi, H., *Garg, V., Matsuoka, R., Thomas, T., and Srivastava, D.  “A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects.”  Science 283:1158-1161 (1999). *co-first authors  PMID: 10024240

2.  Garg, V., Yamagishi, C., Hu, T., Kathiriya, I.S., Yamagishi, H., and Srivastava, D.  “Tbx1, a DiGeorge syndrome candidate gene, is regulated by Sonic Hedgehog during pharyngeal arch development.”  Developmental Biology 235:62-73 (2001).  PMID: 11412027

3.  Kunte, A., Ivey, K., Yamagishi, C., Garg, V., Yamagishi, H., and Srivastava, D.  “A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L.”  Mechanisms of Development 108:81-92 (2001).  PMID: 11578863

4.  Srivastava, D. and Garg, V.  “Potential for fetal gene therapy in congenital heart disease.” Frontiers in Fetal Health 3(7):211-212 (2001).

5.  Garg, V., Kathiriya, I.S., Barnes, R., Schluterman, M.K., King, I.N., Butler, C. A., Rothrock, C.R., Eapen, R.S., Hirayama-Yamada, K., Joo, K., Matsuoka, R., Cohen, J.C., and Srivastava, D.  “GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5”.  Nature 424(6947):443-447 (2003).  PMID: 12845333

6.  Garg, V. and Srivastava, D.  “Genetic Underpinnings of Cardiogenesis and Congenital Heart Disease”. Eds. C. Patterson and M. Runge in Principles of Molecular Cardiology.  Springer-Verlag, New York (2005).

7.  Garg, V., Muth, A.N., Ransom, J.F., Schluterman, M.K., Barnes, R., King, I.N., Grossfeld, P.D., and Srivastava, D.  “Mutations in NOTCH1 Cause Aortic Valve Disease”.  Nature 437(7056):270-274 (2005).  PMID: 16025100

8.  Garg, V.  “Insights into the Genetic Basis of Congenital Heart Disease”. Cellular Molecular Life Sciences.  63(10):1141-1148 (2006).  PMID: 16568242

9.  Garg, V.  “Molecular Genetics of Aortic Valve Disease”.  Curr Opin in Cardiology 21(3): 180-184 (2006).  PMID: 16601454

10.  Schluterman, M.K., Krysiak, A.E., Kathiriya, I.S., Abate, N., Chandalia, M., Srivastava, D., and Garg, V. “Screening and Biochemical Analysis of GATA4 Sequence Variations in Patients with Congenital Heart Disease”.  Am J Med Genet A 143(8):817-823 (2007).  PMID: 17352393

11.  Rajagopal, S.K., Ma, Q., Obler, D., Shen, J., Manichaikul, A., Tomita-Mitchell, A., Boardman, K, Briggs, C, Garg, V., Srivastava, D., Goldmuntz, E., Broman, K.W., Benson, D.W., Smoot, L., and Pu, W.T.  2007. Spectrum of Heart Disease Associated with Murine and Human GATA4 Mutation.  J Mol Cell Cardiol 43(6):677-85 (2007).  PMID: 17643447

12.  Tomita-Mitchell, A., Maslen, C.L., Morris, C.D., Garg, V., and Goldmuntz, E.  “GATA4 Sequence Variants in Patients with Congenital Heart Disease” J Med Genet 44(12): 779-783 (2007).  PMID: 18055909

13. Richards, A., Jaeckle, L., Nichols, H., Crider, B., Elder, F., Hauser, N., Zinn, A.R., and Garg, V. Cryptic chromosomal abnormalities identified in children with congenital heart disease and additional birth anomalies.  Pediatr Res 64(4):358-363 (2008).  PMID: 18535492

14.  Ransom, J.F., King, I.N., Garg, V., and Srivastava, D.  “A Rare Human Sequence Variation Reveals Myocardin Autoinhibition” J Biol Chem, 283(51):35845-52 (2008).  PMID: 18852265

15.  Maitra, M., Schluterman, M.K., Nichols, H., Richardson, J.A., Lo, C., Srivastava, D. and Garg, V.  “Interaction of Gata4 and Tbx5 is critical for normal cardiac development” Dev Biol, 326(2):368-77 (2009).  PMID: 19084512

16.  Pan, H., Richards, A.A., Xhu, X., Joglar, J.A., Yin, H.L., and Garg, V.  “A novel mutation in LAMIN A/C is associated with isolated early-onset atrial fibrillation and progressive atrioventricular block followed by cardiomyopathy and sudden cardiac death” Heart Rhythm, 6(5):707-710 (2009).  PMID: 19328042

17.  Richards A.A. and Garg, V.  Genetics of Congenital Heart Disease.  Current Cardiology Reviews, 6(2):91-97 (2010).

18.  Garg, V.  “Growth of the Normal Human Heart” Ed. Victor R. Preedy.  Handbook of Growth and Growth Monitoring in Health and Disease. Springer, New York, in press (2010).

19.  Maitra, M., Koenig, S., Srivastava, D. and Garg, V. “GATA6 Sequence Variations in Human Congenital Heart Disease” Pediatr Res in press (2010).

20.  Yu, S., Poe, B., Schwarz, M., Elliot, S., Albertine, K.H., Fenton, S., Garg, V., and Moon, A.M.  “Fetal and post-natal lung defects reveal a novel and required role for Fgf8 in lung development” Dev Biol, in press (2010).

21.  McBride, K.L. and Garg, V.  Impact of Mendelian Genetics in Cardiovascular Disease.  Annals of New York Acad Sci, in press (2010).