Endocrinology, Metabolism & Diabetes Research and Innovations :: Nationwide Children's Hospital, Columbus, Ohio

Endocrinology, Metabolism and Diabetes Research and Innovation

Clinician scientists within Endocrinology are committed to improving care for children. Clinical-based research studies are informing new treatment strategies involving new technologies. Information about some of the latest research done by our hospital can be found here. 

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How to Accurately Determine Testicular Volume Without Ultrasound
The most commonly used clinical methods can overestimate volumes by 250 percent, but a new calculator gives providers much more reliable values.

Is Central Adrenal Insufficiency Over-diagnosed in Prader-Willi Syndrome?
A first-of-its-kind study shows poor agreement between two testing methods for central adrenal insufficiency– suggesting one of the tests may be preferred to avoid over-diagnosis and treatment in this patient population.

A Vulnerable Population Lacks Access To Beneficial Puberty-Blocking Hormone Therapy
Insurance companies often decline to cover costs of therapy for transgender youth.

Finding Better Markers of Cardiovascular Risk in Pediatric Type 1 Diabetes
Children and adolescents with type 1 diabetes are at risk for cardiovascular disease. Are there ways to determine who is at greatest risk, and who benefits most from early intervention?

Hormonal Contraception Safer Than Expected for Women With Diabetes
Women with diabetes often fall through the cracks when it comes to prescription contraception. A new study illuminates the issues and highlights safe options.

Endocrinology Issues in Children With Williams Syndrome
The 2016 Annual Williams Syndrome Association Conference included a presentation on the importance of including endocrinologists as part of a multidisciplinary care team.

Bone Turnover Markers Can Help Monitor Response in Children With Bone Fragility Treated With Bone-Strengthening Therapy
While the interpretation of bone turnover markers in growing children can be complicated, a study demonstrates the clinical usefulness of these markers, as marker indexes are suppressed during bisphosphonate treatment.

Myxedema Coma: A Cause of Altered Mental Status in Children
A case study highlights the importance of evaluating thyroid function when a child presents with acute altered mental status, even if the child has not previously been diagnosed with hypothyroidism.

Should Hormone Therapy be Considered for Inappropriate Sexual Behavior in Adolescents With Autism Spectrum Disorder?
Families worry when children with autism spectrum disorder display inappropriate sexual behaviors, but specialists say hormonal suppression should not be the first-line approach.

DSD Clinical Studies

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