Purpose of study:
The purpose of this study is to determine if there are differences in velopharyngeal (palate) function in children with 22q11.2 deletion syndrome (velocardiofacial/DiGeorge syndrome) when compared to children with cleft palate and controls.
Who can participate:
Children with a diagnosis of 22q11.2 deletion syndrome (including children with velocardiofacial or DiGeorge syndrome).
Children with repaired cleft palate without a syndrome.
Children must be ages 4-18 years, have normal hearing, and speak English.
What will happen during the study:
Children will be asked to come to Nationwide Children's for a visit that will include:
Making a recording of your child's voice? while they repeat words, name pictures, and wear a special microphone on their head.
Asking your child to repeat words and sounds while we measure the amount of air that comes out of your child's nose and mouth when they talk.
Asking your child to repeat words and sentences while a tiny camera looks into their nose to see how your child's palate and throat move when they talk.
Being in the study takes about 1 hour. There is no cost to be in the study. We will tell you the results of the tests when your child completes the study. Compensation for time and travel is available.
Who to contact:
Adriane Baylis, PhD, CCC-SLP