Clinical Research Study Viewer

Heavy Menstrual Bleeding Study for Adolescent Girls

What is the purpose of the study?

Heavy menstrual bleeding is the most common symptom in females with bleeding disorders, and it can have a significant impact on a person's quality of life. The purpose of this study is to learn more about a drug called tranexamic acid (TA), otherwise known as Lysteda, and to determine whether or not this drug can decrease menstrual blood loss in young women to increase their quality of life.

TA is a hormone-free fmedicine that has been approved by the FDA for use in patients who are at least 18 years of age, but not for younger patients.

Who is eligible for the study?

Females ages 10-19 years old who experience heavy menstrual bleeding and are non-smokers are eligible for this study.

What will happen during this study?

Participation in this study will last for about six (6) months. There are two required study visits at which a physical exam will be completed and blood will be drawn, and there are four telephone calls.

All patients will take tranexamic acid (TA) during their menses for three (3) months. The study will also include surveys each month to record the heaviness of menstrual bleeding and how it affects everyday life (school, extracurrical activities, etc.)

What are the benefits of participating?

Possible benefits to the participant may be an improvement in quality of life and a decrease in menstrual blood loss. Additionally, for their time and inconvenience, participants will receive gift cards after completing several study milestones. 

Who can I contact if I want to learn more?

If you want to learn more or are interested in participating in this study, please contact either of the following two individuals:

Heidi Ziegler, RN
Phone: (614) 722-3883
Email: Heidi.Ziegler@NationwideChildrens.org

Sarah O'Brien, MD
Phone: (614) 722-6230
Email: Sarah.O'Brien@NationwideChildrens.org

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000