Clinical Research Study Viewer

Effects of Serotonin Reuptake Inhibitors on Bone in Depressed Youth

Purpose of study:

Some studies of older adults taking medications known as Selective Serotonin Reuptake Inhibitors (SSRIs) suggest that they may be at greater risk for broken bones. Dr. Gracious is interested in finding out if adolescents and young women who have been taking an SSRI for at least two years are at risk for broken bones because of a decrease in their bone density.

Who can participate: 

Caucasian adolescents ages 7 to 11 and young women ages 16 to 20 years of age who have been taking one of the listed antidepressant medications for at least 2 years:

Citalopram (Celexa) Escitalopram (Lexapro)
Fluvoxamine (Luvox) Fluoxetine (Prozac)
Paroxetine (Paxil) Sertraline (Zoloft)?

What will happen during the study: 

Qualified volunteers will have a comprehensive medical history of potential factors affecting bone health, a limited physical examination, a bone density test, hand x-ray, a blood draw, and a urine test at no cost to you. Participants will be compensated for their time. This study involves one visit which takes about an hour and a half to two hours. ?

Who to contact: 

Rachel Jones (614) 722-3221? 

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000