Clinical Research Study Viewer

Children Needed for MRI-Speech Study

Who are we looking for?

Children ages 4-12 years old with 22q11.2 deletion syndrome (also known as velocardiofacial/DiGeorge syndrome). Children who have a pharyngeal flap or sphincter pharyngoplasty are not eligible. Children who previously had a palate repair surgery (e.g., Furlow) are also not eligible to participate.

What is involved?

  • 15-minute speech video recording (repeating words and sentences)
  • Oral exam
  • Medical history review
  • 15-minute magnetic resonance imaging (MRI) scan of the head while the child is quiet and while the child is saying sounds

Before the MRI scan, participants will be able to practice lying in an MRI simulator to feel, see and hear what an MRI machine is like. All MRI scans will be done while the child is awake, without any sedation or anesthesia.

A parent or legal guardian may be present with the child for the MRI scan, after passing an initial MRI safety screening.

All tests will be done at Nationwide Children’s Hospital. All study procedures (including paperwork and medical history review) will take up to two hours total and can be completed in one or two visits.

What are the benefits of participating?

  • Participation is completely voluntary and will be at no cost to you.
  • The MRI does not use radiation and is safe for children.
  • Whether or not you choose to participate will not impact your care at Nationwide Children's Hospital.
  • Participants will be compensated for their time and ground travel.

How do I participate or find out more?

Contact Adriane Baylis, PhD, by phone at (614) 722-3895 or by e-mail at



Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000