Clinical Research Study Viewer

Anesthesia during neurophysiologic monitoring in scoliosis patients: volatile agents versus total intravenous anesthesia

Purpose of study:

When patients have spinal surgery, electrodes are placed in many places on the body to measure the nerve signals coming from the spinal cord. This is called motor evoked potentials (MEP) and somatosensory evoked potentials (SSEP). The anesthesia that is used to keep patients asleep during surgery can either be given through an intravenous catheter (IV) or inhaled through the breathing tube. Many hospitals only use IV anesthesia because they feel that measuring MEP and SSEP is easier using IV anesthesia. At this hospital we typically use inhaled anesthesia and are able to successfully measure MEP and SSEP. This is a study to find out if one method of anesthesia is better than the other for measuring MEP and SSEP.

Who can participate: 

Patients with idiopathic scoliosis

What will happen during the study: 

This study will consist of one visit and will last from the time you are taken back to the operating room until the day after your surgery. You will be taken to surgery and be put to sleep with gas that you inhale. After you are asleep you will have an IV started and a tube will be placed in your throat to help you breathe. You will receive anesthesia either through the IV or through the breathing tube, which will keep you asleep and without pain until the surgery is finished. Electrodes will be placed on your head, trunk, arms, and legs to measure MEP and SSEP. MEP and SSEP will be measured 4 times during the surgery. You will also have about 6 mls (½ tablespoon) of blood taken right after you go to sleep, at the end of your surgery, and the day after your surgery. The total amount of blood will not be more than about 20 mls or 1½ tablespoons. This blood will be taken from your IV so you will not have an extra needle stick.

Who to contact: 

Julie Rice, RN, BSN, CCRC 355-3142 

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000