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A comparison of functional magnetic resonance imaging (fMRI) findings in children with and without a history of early exposure to general anesthetics

Purpose of study:

We want to find out if there are changes in the way the brain works in children who received anesthesia at a very young age. By taking MRI pictures of a child’s brain while he or she is pushing a button, and comparing those pictures to a child who never had anesthesia, we hope to see if there are differences in how the brain works.

Who can participate:

Children ages 10-17 years.

What will happen during the study:

First, the child will be given a tour of the MRI room. After the tour, we teach him/her how to push the button. The child will be shown a variety of shapes on a computer screen. He/she will be told to push the button each time a shape appears on the screen, except when the shape is a small square. The child will be given a chance to practice this task to make sure he/she understands the instructions.


Next, the child will be moved into the MRI machine to have the pictures taken. While in the MRI machine the child will lay on his/her back and a special MRI head-holder will be positioned around his/her head. The child will view the shapes through a mirror that sits on the head holder. It will take approximately one hour to take the pictures.

Who to contact:

Julie Rice, BSN, RN, CCRC

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000