Carlo Di Lorenzo, MD

Carlo Di Lorenzo, MD, is Chief of the Division of Pediatric Gastroenterology at Nationwide Children's Hospital and Professor of Clinical Pediatrics at The Ohio State University College of Medicine. Dr. Di Lorenzo has been among the first clinical investigators to assess the diagnostic value of antroduodenal and colonic manometry and to use the electronic barostat to assess visceral sensitivity in children. He co-authored the only book on pediatric gastrointestinal motility and has published more than 140 peer-reviewed original articles and 80 chapters, invited reviews and editorials.

Named among the “Best Doctors in America," Dr. Di Lorenzo serves on the editorial board of the Journal of Pediatric Gastroenterology, Hepatology and Nutrition and the Journal of Neurogastroenterology and Motility. He has functioned as a grant reviewer for the National Institutes of Health and abstract reviewer for the American Gastroenterological Association (AGA). Dr. Di Lorenzo has also held prominent roles in numerous national and international organizations and work groups, including:
• NASPGHAN President
• Chair of the American Academy of Pediatrics (AAP) subcommittee to develop evaluation and treatment guidelines for functional abdominal pain
• Chair of the Functional Gastrointestinal Disorders and Neurogastroenterology working group of the second World Congress of Pediatric Gastroenterology
• Chair of the American Neurogastroenterology and Motility Society (ANMS) committee for the development of minimal standards for motility testing in children
• Chair of the Adolescent Committee of the Rome III criteria
• Chair of the Growth, Development and Child Health Section of the American Gastroenterology Association
• Council member of the Functional Bowel Group
• Member of the American Board of Pediatrics’ Pediatric Gastroenterology Sub-board
• Member of the Functional GI Disorders and Motility Disorders Working Group of the National Commission on Digestive Diseases (NCDD)
• ANMS council member
• Member of U.S. News & World Report’s digestive disorders working group for America’s best children’s hospitals

Gender:

• Male

Languages Spoken:

• English
• Italian
• French

Research Center:

• Hospital-Based Research Faculty

Medical School

• 2nd University of Naples - Italy
  Date Completed: 07/31/1984

Internship

• 2nd University of Naples - Italy
  Date Completed: 07/31/1986

Fellowship

• Hospital Universitaire des Enfants - Brussels
  Date Completed: 12/31/1986

Fellowship

• University of Southern California County Hospital
  Date Completed: 04/30/1988

Residency

• 2nd University of Naples - Italy
  Date Completed: 07/31/1988

Fellowship

• Harbor UCLA Medical Center
  Date Completed: 06/30/1990

Department:

• Pediatrics

Section:

• Gastroenterology/Nutrition

Speciality:

• Pediatric Gastroenterology
  

Date of Appointment at Nationwide Children’s Hospital:

• 08/27/2004

• Mugie SM, Machado RS, Mousa HM, Punati JB, Hogan M, Benninga MA, Di Lorenzo C. 2012. Ten-Year Experience Using Antegrade Enemas in Children.  Journal of Pediatrics. Vol. 161, no. 4. (October): 700-4.
• Burgers R, Levin AD, Di Lorenzo C, Dijkgraaf MG, Benninga MA. 2012. Functional Defecation Disorders in Children: Comparing the Rome II with the Rome III Criteria.  Journal of Pediatrics. Vol. 161, no. 4. (October): 615-620.
• Chogle A, Sztainberg M, Youssef NN, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C, Saps M. 2012. Accuracy of Pain Recall in Children.  Journal of Pediatric Gastroenterology and Nutrition. Vol. 55, no. 3. (September): 288-291.
• Gomez,Roberto; Fernandez,Sergio; Aspirot,Ann; Punati,Jaya; Skaggs,Beth; Mousa,Hayat; di Lorenzo,Carlo. 2012. Effect of Amoxicillin/Clavulanate on Gastrointestinal Motility in Children.  JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. Vol. 54, no. 6. (June): 780-784.
• Burgers,Rosa; Bonanno,Elvira; Madarena,Elisa; Graziano,Francesca; Pensabene,Licia; Gardner,William; Mousa,Hayat; Benninga,Marc,A; di Lorenzo,Carlo. 2012. The care of constipated children in primary care in different countries.  ACTA PAEDIATRICA. Vol. 101, no. 6. (June): 677-680.
• Camilleri,Michael; di Lorenzo,Carlo. 2012. Brain-Gut Axis: From Basic Understanding to Treatment of IBS and Related Disorders.  JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. Vol. 54, no. 4. (April): 446-453.
• Rippel,Sara,W; Acra,Sari; Correa,Hernan; Vaezi,Michael; di Lorenzo,Carlo; Walker,Lynn,S. 2012. Pediatric Patients With Dyspepsia Have Chronic Symptoms, Anxiety, and Lower Quality of Life as Adolescents and Adults.  GASTROENTEROLOGY. Vol. 142, no. 4. (April): 754-761.
• Liem,O; Burgers,R,E; Connor,F,L; Benninga,M,A; Reddy,S,N; Mousa,H,M; Di Lorenzo,C. 2012. Solid-state vs water-perfused catheters to measure colonic high-amplitude propagating contractions.  NEUROGASTROENTEROLOGY AND MOTILITY. Vol. 24, no. 4. (April): 345-e167.
• Jadcherla,Sudarshan,R; Peng,Juan; Moore,Rebecca; Saavedra,Jason; Shepherd,Edward; Fernandez,Soledad; Erdman,Steven,H; Dilorenzo,Carlo. 2012. Impact of Personalized Feeding Program in 100 NICU Infants: Pathophysiology-based Approach for Better Outcomes.  JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. Vol. 54, no. 1. (January): 62-70.
• Mugie,Suzanne,M; di Lorenzo,Carlo; Benninga,Marc,A. 2011. Constipation in childhood.  NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. Vol. 8, no. 9. (September): 502-511.
• Jadcherla,Sudarshan,R; Peng,Juan; Chan,Chin,Yee; Moore,Rebecca; Wei,Lai; Fernandez,Soledad; Di Lorenzo,Carlo. 2011. Significance of Gastroesophageal Refluxate in Relation to Physical, Chemical, and Spatiotemporal Characteristics in Symptomatic Intensive Care Unit Neonates.  PEDIATRIC RESEARCH. Vol. 70, no. 2. (August): 192-198.
• Sood MR, Di Lorenzo C, Hyams J, Miranda A, Simpson P, Mousa H, Nurko S. 2011. Beliefs and Attitudes of General Pediatricians and Pediatric Gastroenterologists Regarding Functional Gastrointestinal Disorders: A Survey Study.  Clin Pediatr (Phila).
• Burgers R, Di Lorenzo C, Rao SS. 2011. Colonic monometry. In GI Motility Testing: A Laboratory and Office Handbook. Edited by Parkman HP, McCalum RW, Rao SS. Thorofare, NJ: SLACK Inc..
• Mugie SM, Benninga MA, Di Lorenzo C. 2011. Epidemiology of constipation in children and adults: A systematic review.  Best Pract Res Clin Gastroenterol. Vol. 25, no. January: 3-18.
• Dinning PG, Di Lorenzo C. 2011. Colonic dysmotility in constipation.  Best Pract Res Clin Gastroenterol. Vol. 25, no. January: 89-101.
• Green AD, Alioto A, Mousa H, Di Lorenzo C. 2011. Severe pediatric rumination syndrome: successful interdisciplinary inpatient management.  J Pediatr Gastroenterol Nutr. Vol. 52, no. January: 414-418.
• Vd Baan-Slootweg OH, Liem O, Bekkali N, van Aalderen WM, Rijcken TH, Di Lorenzo C, Benninga MA. 2011. Constipation and Colonic Transit Times in Children With Morbid Obesity.  J Pediatr Gastroenterol Nutr. Vol. 52, no. January: 442-445.
• Kaul A, Garza JM, Connor FL, Cocjin JT, Flores AF, Hyman PE, Di Lorenzo C. 2011. Colonic Hyperactivity Results in Frequent Fecal Soiling in a Subset of Children After Surgery for Hirschspring Disease.  J Pediatr Gastroenterol Nutr. Vol. 52, no. January: 433-436.
• Saps M, Di Lorenzo C. 2011. Gastric motililty disorders. In Wyllie R, Hyams JS, Kay M Pediatric Gastrointestinal and Lliver Disease. 4th ed. Philadelphia, PA: Elsevier Sauders Inc..
• Binkovitz LA, Lorenz EA, Di Lorenzo C, Kahwash S. 2010. Pediatric eosinophilic esophagitis: radiologic findings with pathologic correlation.  Pediatr Radiol. Vol. 40, no. December: 714-719.
• Aziz S, Moiz Fakih HA, Di Lorenzo C. 2010. Bowel Habits and Toilet Training in Rural and Urban Dwelling Children in a Developing Country.  J Pediatr.
• Liem O, van den Berg MM, Mousa HM, Youssef NN, Langseder AL, Benninga MA, Di Lorenzo C. 2010. Distention of the colon is assosicated with initiation of propagated contractions in children.  Neurogastroenterol Motil. Vol. 22, no. August: 19-23.
• Fernandez S, Aspirot A, Kerzner B, Friedlander J, Di Lorenzo C. 2010. Do Some Adolescents with Rumination Syndrome Have "Supragastric Vomiting"?.  J Pediatr Gastroenterol Nutr. Vol. 50, no. June: 103-105.
• Pena EM, Parks VN, Peng J, Fernandez SA, Di Lorenzo C, Shaker R, Jadchera SR. 2010. Lower Esophageal Sphincter (LES) Relaxation Reflex kinetics: Effects of Peristaltic Reflexes and Maturation in Human Premature Neonates.  Am J Physiol Gastrointest Liver Physiol. Vol. 299, no. January: GI386-395.
• Chogle A, Dhroove G, Sztainberg M, Di Lorenzo C, Saps M. 2010. How Reliable are the Rome III Criteria for the Assessment of Functional Gastrointestinal Disorders in Children?.  Am J Gastroenterol Nutr. Vol. 105, no. January: 2697-2701.
• Di Lorenzo C, Youssef NN. 2010. Diagnosis and management of intestinal motility disorders.  Semin Pediatr Surg. Vol. 19, no. January: 50-58.
• Gomez R, Mousa H, Liem O, Hayes J, Di Lorenzo C. 2010. How Do Antegrade Enemas Work? Colonic Motility in Response to Administratin of Normal Saline Solution Into the Proximal Colon.  J Pediatr Gastroenterol Nutr. Vol. 51, no. January: 741-746.
• Burger R. Liem O, Canon S, Mousa H, Benninga MA, Di Lorenzo C, Koff SA. 2010. Effect of rectal distention on lower urinary tract function in children.  J Urol. Vol. 184 (4 Suppl), no. January: 1680-1685.
• Vandenplas Y, Rudolph CD, Di Lorenzo C, Hassall E, Liptak G, Mazur L, Sondheimer J, Staiano A, Thomson M, Veereman-Wauters G, Wenzl TG. 2009. Pediatric Gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition.  J Pediatr Gastroenterol Nutr. Vol. 49, no. September: 498-547.
• Connor FL, Hyman PE, Faure C, Tomomasa T, Pehlivanov N, Janosky J, Rudolph C, Liem O, Di Lorenzo C. 2009. Interobserver variability in antroduodenal manometry.  Neurogastroenterol Motil. Vol. 21, no. July: 500-507.
• Yacob D, Di Lorenzo C. 2009. Functional abdominal pain: All roads lead to Rome (Criteria).  Pediatric Annals. Vol. 38, no. 5. (May): 253-258.
• Saps M, Pensabene L, Turco R, Staiano A, Cupuro D, Di Lorenzo C. 2009. Rotavirus gastroenteritis: precursor of functional gastrointestinal disorders?.  J Pediatr Gastroenterol Nutr. Vol. 49, no. January: 580-583.
• van den Berg M, Di Lorenzo C, Mousa H, Benninga M, Boeckxstaens G, Luquette M. 2009. Morphological Changes of the Enteric Nervous System, Interstitial Cells of Cajal, and Smooth Muscle in Children With Colonic Motility Disorders.  J Pediatr Gastroenterol Nutr. Vol. 48, no. January: 22-29.
• Jadcherla SR, Stoner E, Gupta A, Bates DG, Fernandez S, Di Lorenzo C, Linscheid T. 2009. Evaluation and management of neonatal dysphagia: impact of pharyngoesophageal motility studies and multidisciplinary feedings strategy.  J Pediatr Gastroenterol Nutr. Vol. 48, no. January: 186-192.
• Saps M, Youssef N, Miranda A, Nurko S, Hyman P, Cocjin J, Di Lorenzo C. 2009. Multicenter, randomized, placebo-controlled trial of amitriptyline in children with functional gastrointestinal disorders.  Gastroenterology. Vol. 137, no. January: 1261-1269.
• Aspirot A, Fernandez S, Di Lorenzo C, Skaggs B, Mousa H. 2009. Antegrade enemas for defecation disorders: do they improve the colonic motility?.  J Pediatr Surg. Vol. 44, no. January: 1575-1580.
• Wald ER, Di Lorenzo C, Cipriani L, Colborn DK, Burgers R, Wald A. 2009. Bowel habits and toilet training in a diverse population of children.  J Pediatr Gastroenterol Nutr. Vol. 48, no. January: 294-298.
• Connor FL, Hyman PE, Faure C, Tomomasa T, Pehlivanov N, Janosky J, Rudolph C, Liem O, Di Lorenzo C. 2009. Interobserver variability in antroduodenal manometry.  Neurogastroenterol Motil. Vol. 21, no. January: 500-507.
• Nurko S, Di Lorenzo C. 2008. Functional abdominal pain: time to get together and move forward.  J Pediatr Gastroenterol Nutr. Vol. 47, no. 5. (November): 679-680.
• Saps M, Seshadri R, Sztainberg M, Schaffer G, Marshall BM, Di Lorenzo C. 2008. A Prospective School-based Study of Abdominal Pain and Other Common Somatic Complaints in Children.  J Pediatr.
• Liem O, Harman J, Benninga M, Kelleher K, Mousa H, Di Lorenzo C. 2008. Health Utilization and Cost Impact of Childhood Constipation in the United States.  J Pediatr.
• Nurko S, Youssef NN, Sabri M, Langseder A, McGowan J, Cleveland M, Di Lorenzo C. 2008. PEG3350 in the treatment of childhood constipation: a multicenter, double-blinded, placebo-controlled trial.  J Pediatr. Vol. 153, no. 2. (August): 254-261.
• Sabri M, Di Lorenzo C, Henderson W, Thompson W, Barksdale E Jr, Khan S. 2008. Colon cleansing with oral sodium phosphate in adolescents: dose, efficacy, acceptability, and safety.  Am J Gastroenterol. Vol. 103, no. 6. (June): 1533-1539; quiz 1540.
• Saps M, Pensabene L, Di Martino L, Staiano A, Wechsler J, Zheng X, Di Lorenzo C. 2008. Post-infectious functional gastrointestinal disorders in children.  J Pediatr. Vol. 152, no. 6. (June): 812-816.
• Saps M, Bolioli P, Espana M, Marshall BM, Di Lorenzo C. 2008. Cost and consultation patterns of abdominal pain in Uruguayan children.  J Pediatr Gastroenterol Nutr. Vol. 46, no. 2. (February): 159-163.
• Saps M, Pensabene L, Staiano A, Weschler J, Zheng XT, Di Lorenzo C. 2008. Postinfectious functional gastrointestinal disorders in children.  J Pediatr 152.
• Mousa H, Di Lorenzo C. 2008. Motility disorders. In Intestinal failure: diagnosis, management and transplantation. Edited by Langnas AN, Goulet O, Quigley EMM, Tappenden KA. Malden, MA: Blackwell Publishing, Inc.
• Saps M, Blank C, Khan S, Seshadri R, Marshall B, Bass L, Di Lorenzo C. 2008. Seasonal variation in the presentation of abdominal pain.  J Pediatr Gastroenterol Nutr. Vol. 46, no. January: 279-284.
• Liem O, Mousa HM, Benninga MA, Di Lorenzo C. 2008. Safety and Efficacy of Tegaserod in Children.  J Pediatr Gastroenterol Nutr. Vol. 46, no. 1. (January): 54-58.
• Camilleri M, Bharucha AE, Di Lorenzo C, Hasler WL, Prather CM, Rao SS, Wald A. 2008. American Neurogastroenterology and Motility Society consensus statement on intraluminal measurement of gastrointestinal and colonic motility in clinical practice.  Neurogastroenterol Motil 20.
• Khan S, Campo J, Bridge JA, Chiappetta LC, Wald A, di Lorenzo C. 2007. Long-term outcome of functional childhood constipation.  Digestive Diseases and Sciences. Vol. 52, no. 1. (January): 64-69.
• Saps M, Di Lorenzo C. 2007. Probiotics for abdominal pain disorders in children--safe to use but are they helpful?.  Nature Clinical Practice Gastroenterology & Hepatology. Vol. 4, no. 8. (January): 430-431.
• Mousa H, DiLorenz C. 2007. Intestinal Failure: Diagnosis, Management and Transplantation "Motility Disorders". Boston, MA: Blackwell Publishing.
• van den Berg MM, Hogan M, Mousa HM, Di Lorenzo C. 2007. Colonic manometry catheter placement with primary fluoroscopic guidance.  Digestive Diseases Sciences. Vol. 52, no. 9. (January): 2282-2286.
• Campo JV, Bridge J, Lucas A, Savorelli S, Walker L, Di Lorenzo C, Iyengar S, Brent DA. 2007. Physical and emotional health of mothers of youth with functional abdominal pain.  Arch Pediatr Adolesc Med. Vol. 161, no. 2. (January): 131-137.
• Liem O, Benninga MA, Mousa HM, Di Lorenzo C. 2007. Novel and alternative therapies for childhood constipation.  Current Gastroenterology Reports. Vol. 9, no. 3. (January): 214-218.
• Liem O, Di Lorenzo C, Taminiau JAJM, Mousa HM, Benninga, MA. 2007. Current treatment of Childhood Constipation.  Annales Nestle. Vol. 65, no. January: 73-79.
• Mousa H, Caniano DA, Alhajj M, Gibson L, Di Lorenzo C, Binkowitz L. 2006. Effect of Nissen fundoplication on gastric motor and sensory functions.  J Pediatr Gastroenterol Nutr 43.
• Di Lorenzo C, Blank C, Saps M. 2006. Children. In Therapy of Digestive Disorders. Philadelphia: Elsevier, Inc..
• Mousa HM, van den Berg MM, Caniano DA, Hogan M, Di Lorenzo C, Hayes J. 2006. Cecostomy in children with defecation disorders.  Dig Dis Sci 51.
• van den Berg MM, Hogan M, Caniano DA, Di Lorenzo C, Benninga MA, Mousa HM. 2006. Colonic manometry as predictor of cecostomy success in children with defacation disorders.  J Pediatr Surg 41.
• Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, Walker LS. 2006. Childhood functional gastrointestinal disorders: child/adolescent.  Gastroenterology 130.
• Saps M, Sztainberg M, Di Lorenzo C. 2006. A prospective community-based study of gastroenterological symptoms in school-age children.  J Pediatr Gastroenterol Nutr 43.
• Di Lorenzo C, Rasquin A, Forbes D, Guiraldes E, Hyams JS, Staiano A, Walker LS. 2006. Childhood functional gastrointestinal disorders: child/adolescent. In Rome III: The Functional Gastrointestinal Disorders. McLean: Degnon Associates.
• van den Berg MM, Benninga MA, Di Lorenzo C. 2006. Epidemiology of childhood constipation: a systematic review.  Am J Gastroenterol 101.
• van den Berg MM, van Rossum CH, de Lorijn F, Reitsma JB, Di Lorenzo C, Benninga MA. 2005. Functional Constipation in Infants: A Follow-Up Study.  J Pediatr 147.
• Pensabene L, Brundler MA, Bank JM, Di Lorenzo C. 2005. Evaluation of mucosal eosinophils in the pediatric colon.  Dig Dis Sci 50.
• Saps M, Di Lorenzo C. 2005. Interobserver and Intraobserver Reliability of the Rome II Criteria in Children.  Am J Gastoenterol 100.
• Di Lorenzo C, Colletti RB, Lehmann HP, Boyle JT, Gerson WT, Hymans JS, Squires RH Jr, Walker LS, Kanda PT. 2005. Chronic Abdominal Pain In Children: A Technical Report of the American Academy of Pediatrics and the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition: AAP Subcommittee and NASPGHAN Committee on Chronic Abdominal Pain.  J Pediatr Gastroenterol Nutr 40.
• Di Lorenzo C, Colletti RB, Lehmann HP, Boyle JT, Gerson WT, Hyams JS, Squires RH Jr, Walker LS, Kanda PT. 2005. Chronic Abdominal Pain in Children: A Clinical Report of the American Academy of Pediatrics and the North American Society of Pediatric Gastroenterology, Hepatology, and Nutrition: American Academy of Pediatrics Subcommittee on Chronic Abdominal Pain and NASPGHAN Committee on Abdominal Pain.  J Pediatr Gastroenterol Nutr 40.
• Duong M, Dinoulos JG, Gupta A, Bryk T, Saps M, Di Lorenzo C, Sveen A, Waseem M, Kin LL. 2005. Index of Suspicion.  Pediatr Rev 26.
• Sabri M, Davie J, Orlando S, Di Lorenzo C, Ranganathan S. 2004. Gastrointestinal presentation of Langerhans Cell Histiocytosis in a child with perianal skin tags: A case report.  J Pediatr Gastroenterol Nutr 39.
• Connor F, Di Lorenzo C. 2004. Physiology and Pathophysiology: Motility. In Walker WA, Goulet OJ, Kleinman RE, Sanderson IR, Sherman PM, Shneider BL. Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Mangement. 4th ed. Hamilton, ON: BC Decker, Inc..
• Campo JV, Perel J, Lucas A, Bridge J, Ehmann M, Kalas C, Monk K, Axelson D, Birmaher B, Ryan N, Di Lorenzo C, Brent DA. 2004. Citalopram treatment of pediatric recurrent abdominal pain and comorbid internalizing disorders: An exploratory study.  J Am Acad Child Adolesc Psychiatr 43.
• Campo JV, Bridge J, Ehmann M, Altman S, Lucas A, Birmaher B, Di Lorenzo C, Iyengar S, Brent DA. 2004. Recurrent abdominal pain, anxiety, and depression in primary care.  Pediatrics 113.
• Connor F, Di Lorenzo C. 2004. Drug Therapy: Motility. In Walker WA, Goulet OJ, Kleinman RE, Sanderson IR, Sherman PM . Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, mangement. 4th ed. Hamilton, ON: BC Decker, Inc..
• Sabri M, Di Lorenzo C. 2004. Features of entities mimicking gastroesophageal reflux. In The gastroesophageal reflux in infants and children. Eds:Esposito C, Montupet P, Rothenberg S.. Berlin: Springer-Verlag.
• Youssef NN, Pensabene L, Barksdale E Jr, Di Lorenzo C. 2004. Is there a role for surgery beyond colonic aganglionosis and anorectal malformations in children with intractable constipation?.  J Pediatr Surg 39.
• Hussain SZ, Peters JM, Di Lorenzo C. 2004. Tranplante de intestino. In Silva LR. Urgencias clinicas e cirurgicas em gastroenterologia e hepatologia pediatricas. Rio De JaneIro: MEDSI Editora Medica e Cientifica Ltda.
• Saps M, Di Lorenzo C. 2004. Functional abdominal pain and other functional bowel disorders. In Textbook of Pediatric Gastroenterology and Nutrition. Edited by S. Guandalini. London, UK: Taylor & Francis.
• Pensabene L, youssef NN, Di Lorenzo C. 2003. Success of antegrade enemas in children with functional constipation.  Pediatr Med Chir 25.
• Zangen T, Ciarla C, Zangen S, Di Lorenzo C, Flores AF, Cocjin J, Reddy SN, Rowhani A, Schwankovsky L, Hyman PE. 2003. Gastrointestinal motility and sensory abnormalities may contribute to food refusal in medically fragile toddlers.  J Pediatr Gastroenterol Nutr.
• Dorn LD, Campo JC, Thato S, Dahl RE, Lewin D, Chandra R, Di Lorenzo C. 2003. Psychological comorbidity and stress reactivity in children and adolescents with recurrent abdominal pain and anxiety disorders.  J Am Acad Child Adolesc Psychiatry 42.
• Di Lorenzo C. 2003. Motor disorders of the stomach and intestine. In Rudolph et al: Pediatrics. 21st ed. New York City: The McGraw-Hill Companies.
• Khan S, Orenstein SR, Di Lorenzo C, Kocoshis SA, Putnam PE, Sigurdsson L, Shalaby TM. 2003. Eosinophilic esophagitis: Strictures, impactions, dysphagia.  Dig Dis Sci 48.
• Ciamarra P, Nurko S, Barksdale E, Fishman S, Di Lorenzo C. 2003. Internal anal sphincter achalasia in children: Clinical characteristics and treatments with clostridium botulinum toxin.  J Pediatr Gastroenterol Nutr 37.
• Pensabene L, Youssef NN, Griffiths JM, Di Lorenzo C. 2003. Colonic manometry in children with defecatory disorders: role in diagnosis and management.  Am J Gastroenterol 98.
• Khan S, Orenstein SR, Di Lorenzo C, Kocoshis SA, Putnam PE, Sigurdsson L, Shalaby TM. 2003. Eosinophilic esophagitis. Strictures, impactions, dysphasia.  Dig Dis Sci 48.
• Nadler Ep, Boyle P, Murdock AD, Di Lorenzo C, Barksdale EM, Ford HR. 2003. Newborn Endothelin Receptor Type B Mutant (Piebald) Mice have a Higher Resting Anal Sphincter Pressure than Newborn.  Contemp Top Lab Anim Sci 42.
• Saps M, Slivka A, Khan S, Meza MP, Goyal A, Di Lorenzo C. 2003. Pancreatic ascites in an infant: lack of symptoms and normal amylase.  Dig Dis Sci 48.
• Di Lorenzo C. 2003. Approach to the child with constipation and encopreis. In Rudolph et al: Pediatrics. 21st ed. New York City: The McGraw-Hill Companies, Inc..
• Sabri M, Barksdale E, Di Lorenzo C. 2003. Constipation and lack of colonic interstitial cells of Cajal.  Dig Dis Sci 48.
• Hyman PE, Bursch B, Beck D, Di Lorenzo C, Zeltzer LK. 2002. Discriminating pediatric condition falsification from chronic intestinal pseudo-obstruction in toddlers.  Child Maltreat 7.
• Youssef NN, Peters JM, Henderson W, Shutlz-Peters S, Lockhart Dk, Di Lorenzo C. 2002. Dose response of PEG 3350 for the treatment of childhood fecal impaction.  J Pediatr 141.
• Charron M, Di Lorenzo C, Kocoshis S. 2002. CT and 99mTc-WBC vs. colonoscopy in the evaluation of inflammation and complications of inflammatory bowel diseases.  J Gastroenterol 37.
• Di Lorenzo. 2002. Motility disorders. In Pediatric Gastroenterology and Nutrition in Clinical Practice. Edited by Lifschitz C. New York, NY: Marcel Decker, Inc..
• Di Lorenzo C, Hillemeier C, Hyman P, Loening-Baucke V, Nurko S, Rosenburg A, Taminiau J. 2002. Manometry studies in children: minimum standards for procedures.  Neurogastroenterol Motil 14.
• Youssef NN, Di Lorenzo C. 2002. Hirschsprung's Disease. In Burg FD at al: Current pediatric therapy. Philadelphia: W.B. Saunders, Co..
• Youssef NN, Di Lorenzo C. 2002. Anorectal anomalies. In Burg FD at al: Current pediatric therapy. Philadelphia: W.B. Saunders, Co..
• Youssef NN, Barksdale E Jr, Griffiths JM, Flores AF, Di Lorenzo C. 2002. Management of intractable constipation with antegrade enemas in neurologically intact children.  J Pediatr Gastroenterol Nutr 34.
• Mousa H, Hyman PE, Cocjin J, Flores AF, Di Lorenzo c. 2002. Long-term outcome of congenital intestinal pseudo-obstruction.  Dig Dis Sci 47.
• Schwankovsky L, Mousa H, Rowhani A, Di Lorenzo C, Hyman PE. 2002. Quality of life outcomes in congenital chronic intestinal pseudo-obstruction.  Dig Dis Sci 47.
• Sood MR, Cocjin J, Di Lorenzo C, Reddy SN, Flores AF, Hyman PE. 2002. Ileal manometry in children following ileostomies and pull-through operations.  Neurogastroenterol Motil 14.
• Villareal J, Sood M, Zangen T, Flores A, Michel R, Reddy N, Di Lorenzo C, Hyman PE. 2001. Colonic diversion for intractable constipation in children: colonic manometry helps guide clinical decision.  J Pediatr Gastroenterol Nutr 33.
• Charron M, Di Lorenzo C, Kocoshis SA, Hickson MP, Orenstein SR, Goyal A, Khan S, Collins L. 2001. 99mTc antigranulocyte monoclonal antibody imaging for the detection and assessment of inflammatory bowel disease newly diagnosed by colonoscopy in children.  Pediatr Radiol 31.
• Zangen S, Di Lorenzo c, Zangen T, Schwankovsky L, Hyman PE. 2001. Rapid maturation of gastric relaxation in newborn infants.  Ped Res 50.
• Di Lorenzo C. 2001. Pediatric anorectal disorders. In Rao SSC ed. Gastroenterology Clinics of North America "Disorders of the Anorectum". Philadelphia, PA: W.B. Saunders.
• Di Lorenzo c, Youssef NN, Sigurdsson L, Scharff L, Griffiths J, Wald A. 2001. Visceral hyperalgesia in children with functional abdominal pain.  J Pediatr 138.
• Campo JV, Di Lorenzo C, Chiapetta L, Bridge J, Colborn K, Gartner JC, Gaffney P, Kocoshis S, Brent D. 2001. Adult outcomes of pediatric recurrent abdominal pain: do they "just grow out of it"?.  Pediatrics 108.
• Paryzhskaya M, Youssef NN, Di Lorenzo C, Goyal R. 2001. Clofazimine enteropathy in a pediatric bone marrow transplant recipient.  J Pediatr 138.
• Lucanto C, Bauer SB, Flores AF, Hyman PE, Di Lorenzo C. 2000. Hollow viscera neuropathy in children with intractable constipation and urinary tract symptoms.  Dig Dis Sci 45.
• Liptak GS, Baker SS, Colletti RB, Croffie JM, Di Lorenzo C, Ector W, Nurko S. 2000. Constipation. In Moyer VA, Elliott EJ, eds. Evidence-Based Pediatrics and Child Health. London: BMJ Books.
• Orenstein SR, Shalaby TM, Di Lorenzo C, Putnam PE, Sigurdsson L, Kocoshis SA. 2000. The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children.  Am J Gastroenterol 95.
• Khan S, Hyman PE, Di Lorenzo C. 2000. Rumination syndrome in adolescents.  J Pediatr 136.
• Di Lorenzo C, Vasiliauskas E. 2000. Gastrointestinal bleeding. In Berkowitz CD ed. Primary Care Pediatrics. 2nd ed. New York, NY: W.B. Saunders.
• Di Lorenzo C. 2000. Gastroesophageal reflux. In Berkowitz CD ed. Primary Care Pediatrics. 2nd ed. New York, NY: W.B. Saunders.
• Di Lorenzo C, Solzi GF, Flores AF, Schwankovsky L, Hyman PE. 2000. Colonic motilityafter surgery for Hirschsprung's disease.  Am J Gastroenterol 95.
• Charron M, Di Lorenzo C, Kocoshis S. 2000. Is 99mTc WBC scintigraphy useful in children suspected of having inflammatory bowel disease?.  Am J Gastroenterol 98.
• Di Lorenzo C. 1999. Dyspepsia and gastrointestinal motility in children. In Rao SSC, Conklin JL, Johlin FC, Murray JA, Schulze-Delrieu KS, Summers TW, eds: Gastrointestinal motility:tests and problem oriented approach. New York, NY: Plenum Publishing Corporation.
• Chun A, Desautel S, Slivka A, Mitrani C, Starz T, Di Lorenzo C, Wald A,. 1999. Visceral algesia in irritable bowel syndrome, fibromyalgia and sphincter of Oddi dynsfunction type 3: is rectal hyperalgesia specific to irritable bowel syndrome?.  Dig Dis Sci 44.
• Di Lorenzo C. 1999. Pseudo-obstruction: current approaches.  Gastroenterology 116.
• Desautel SG, Slivka A, Hutson WR, Chun A, Mitrani C, Di Lorenzo C, Wald A. 1999. Post-cholecystectomy pain syndrome: pathophysiology of abdominal pain in sphincter of Oddi type III.  Gastroenterology 116.
• Di Lorenzo C. 1999. Clinical approach to pediatric colorectal disorders in children. In Rao SSC, Conklin JL, Johlin FC, Murray JA, Schulze-Delrieu KS, Summers RW eds: Gastrointestinal motility: tests and problem oriented approach. New York, NY: Plenum Publishing Corporation.
• Charron M, Di Lorenzo C, Kocoshis S. 1999. Gastric and small bowel Crohn's disease assessed with leukocytes-Tc(99m) scintigraphy.  Pediatr Surg Int 15.
• Khan S, Lichtman SN, Reyes J, Di Lorenzo C. 1999. Ulcerative colitis after liver transplant and immunosuppression.  J Pediatr Gastroenterol Nutr 28.
• Solzi G, Di Lorenzo C. 1999. Nutcracker esophagus in a child with diabetes mellitus.  J Pediatr Gastroenterol Nutr 29.
• Solzi G, Di Lorenzo C. 1999. Are constipated children different from constipated adults?.  Dig Dis Sci 17.
• Di Lorenzo C, Lucanto C, Flores AF, Idries S, Hyman PE. 1999. The effect of sequential eruthromycin and octreotide on antroduodenal manometry.  J Pediatr Gastroenterol Nutr 29.
• Sigurdsson L, Reyes J, Kocoshis SA, Mazariegos G, Bueno J, Di Lorenzo C. 1999. Intestinal transplantation in children with chronic intestinal pseudo-obstruction.  Gut 45.
• Bueno J, Ohwada S, Kocoshis S, Mazariegos GV, Dvorchik I, Sigurdsson L, Di Lorenzo C, Abu-Elmagd K, Reyes J. 1999. Factors impacting the survival of children with intestinal failure referred for intestinal transplantation.  J Pediatr Surg 34.
• Heikenen JB, Werlin SL, Di Lorenzo C, Hyman PE, Cocjin J, Flores AF, Reddy SN. 1999. Colonic motility in children with repaired imperforated anus.  Dig Dis Sci 44.
• Baker SS, Liptak GS, Colletti RB, Croffie JM, Di Lorenzo C, Ector W, Nurko S. 1999. Constipation in infants and children: evaluation and treatment. A medical position statement of the North American Society for Pediatric Gastroenterology and Nutrition.  J Pediatr Gastroenterol Nutr 29.
• Del Rosario F, Di Lorenzo C. 1999. Achalasia and other motor disorders. In Willie R, Hyams JS eds: Pediatric gastrointestinal disease: pathophysiology, diagnosis, management.. 2nd ed. Philadelphia, PA: W.B. Saunders Company.
• Sigurdsson L, Reyes J, Putnam PE, Del Rosario F, Di Lorenzo C, Orenstein SR, Todo S, Kocoshis S. 1998. Endoscopies in pediatric small intestinal transplant recipients: five years experience.  Am J Gastroenterol 93.
• Hamid SA, Di Lorenzo C, Reddy SN, Flores AF, Hyman PE. 1998. Bisacodyl and high amplitude propagating contractions (HAPCs) in children.  J Pediatr Gastroenterol Nutr 27.
• Di Lorenzo C. 1998. Hirschsprung's Disease. In Altschuler SM and Liacouras CA. London: Churchill Livingstone.
• Di Lorenzo C, Lucanto C, Flores AF, Idries F, Hyman PE. 1998. Effect of octreotide on gastrointestinal motility in children with functional gastrointestinal disorders.  J Pediatr Gastroenterol Nutr 27.
• Rudolph CD, Hyman PE, Altschuler SM, Christensen J, Colletti RB, Cucchiara S, Di Lorenzo C, Flores AF, Hillemeier AC, McCallum RW, Vanderhoof JA. 1997. Diagnosis and treatment of chronic intestinal pseudo-obstruction syndrome in children: report of a consensus workshop.  J Pediatr Gastroenterol Nutr 24.
• Di Lorenzo C. 1997. Functional bowel dissorders. In Gastroenterology Image Collection. Edited by Hyman PE. Philadelphia: Current Medicine.
• Uc A, Hoon A, Di Lorenzo C, Hyman PE. 1997. Normal antroduodenal manometry in children with no upper gastrointestinal symptoms.  Scand J Gastroenterol 32.
• Sigurdsson L, Flores A, Putnam PE, Hyman PE, Di Lorenzo C. 1997. Postviral gastroparesis: presentation, treatment, and outcome.  J Pediatr 131.
• Di Lorenzo C, Reddy SN, Flores AF, Hyman PE. 1997. Is electrogastrography a substitute for manometric studies in children with functional gastrointestinal disorders?.  Dig Dis Sci 42.
• Di Lorenzo C, Hyman PE. 1997. Pediatric application of pH monitoring. In Richter J ed. Ambulatory esophageal pH monitoring: Practical approach and clinical applications. 2 ed. Baltimore, MD: William and Wilkins.
• Orenstein SR, Di Lorenzo C, Orenstein DM, Shalaby TM, Deneault LG, Lutz JW. 1997. Isolated lower esophageal sphincter relaxation as "wave-suppressed" secondary peristalsis.  Dysphagia 12.
• Uc A, Vasiliauskas E, Piccoli DA, Flores AF, Di Lorenzo C, Hyman PE. 1997. Chronic intestinal pseudo-obstruction associated with fetal alcohol syndrome.  Dig Dis Sci 42.
• Di Lorenzo C. 1997. Functional bowel disorders. In Gastroenterology Image Collection. Philadelphia: ..
• Di Lorenzo C. 1996. Motor disorders of the stomach and intestine. In Rudolph et al:Pediatrics. 20th ed. Stamford: Appleton and Lange, Inc..
• Di Lorenzo C. 1996.  Exerpta Medica International Congress Series.
• Di Lorenzo C. 1996. Gastroesophageal reflux. In Berkowitz CD ed. Primary Care Pediatrics. Philadelphia, PA: W.B. Saunders.
• Di Lorenzo C. 1996.  The Esophagogastric Junction.
• Di Lorenzo C. 1996. Approach to the child with constipation and encopresis. In Rudolph et al: Pediatrics. 20th ed. Stamford: Appleton and Lange, Inc..
• Di Lorenzo C. 1996. Economides A. In Foreign bodies in children. Philadelphia, PA: W.B. Sauders.
• Di Lorenzo C, Hyman PE. 1996. Gastrointestinal motility in neonatal and pediatric practice. In Gastroenterology Clinics of North America: Gastrointestinal motility in clinical practice. Philadelphia, PA: W.B. Saunders.
• Di Lorenzo C, Vasiliauskas E. 1996. Gastrointestinal bleeding. In Berkowitz CD ed. Primary Care Pediatrics. New York, NY: W.B. Saunders.
• Di Lorenzo C. 1996.  The Esophagogastric Junction.
• Tomomasa T, Di Lorenzo C, Morikawa A, Uc A, Hyman PE. 1996. Analysis of fasting antroduodenal manometry in children.  Dig Dis Sci 41.
• Di Lorenzo C. 1996. Diagnosis and management of lower gastrointestinal dysfunctions. In Corazziari E ed. NeuroGastroenterology. New York, NY: Walter De Gruyter & Co, Inc..
• Di Lorenzo C, Flores AF, Hyman PE. 1995. Age related changes in colon motility.  J Pediatr 127.
• Di Lorenzo C, Flores AF, Buie T, Hyman PE. 1995. Intestinal motility and jejunal feedings in children with chronic intestinal pseudo-obstruction.  Gastroenterology 108.
• Di Lorenzo C. 1994. Constipation. In Pediatric Gastrointestinal Motility Disorders. New York: Academy Professional Information Services.
• Di Lorenzo C. 1994. Colonic manometry. In Pediatric Gastrointestinal Motility Disorders. New York: Academy Professional Information Services.
• Di Lorenzo C, Flores AF, Tomomasa T, Hyman PE. 1994. Effect of erythromycin on antroduodenal motility in children with chronic functional gastrointestinal symptoms.  Dig Dis Sci 39.
• Di Lorenzo C, Hyman PE, Flores AF, Kashyap P, Tomomasa T, Lo S, WJ Snape Jr. 1994. Antroduodenal manometry in children and adults with severe nonulcer dyspepsia: do they have the same disease?.  Scand J Gastroenterol 29.
• Hyman PE, Di Lorenzo C, Rehm D. 1994. Chronic intestinal pseudo-obstruction (CIP). A cause of intestinal failure.  Transplant Proc 26.
• Di Lorenzo C, Ordein JJ, Hyman PE,. 1993. Cecal fecal bezoar.  J Pediatr Gastroenterol Nutr 16.
• Di Lorenzo C, Flores AF, Reddy SN, Snape WJ Jr, Bazzocchi G, Hyman PE. 1993. Colonic manometry in children with chronic intestinal psuedo-obstruction.  Gut 34.
• Hyman PE, Di Lorenzo C, McAdams L, Flores AF, Tomomasa T, Garvey TQ III. 1993. Clinical response to cisapride in children with chronic intestinal pseudo-obstruction.  Am J Gastroenterol 88.
• Hyman PE, Di Lorenzo C,. 1993. Gastrointestinal motility. In Pediatric gastrointestinal disease: pathophysiology, diagnosis, management.. 1st ed. Philadelphia: W.B. Saunders Company.
• Hyman PE, Di Lorenzo C. 1993. Intestinal pseudo-obstruction. In Pediatric gastrointestinal disease: pathophysiology, diagnosis, management.. 1st ed. Philadelphia: W. B. Saunders Company.
• Di Lorenzo C, Flores AF, Reddy SN, Hyman PE,. 1992. Colonic manometry differentiates causes of intractable constipation in children.  J Pediatr 120.
• Reid B, Di Lorenzo C, Travis L, Flores AF, Grill BB, Hyman PE. 1992. Diabetic gastroparesis due to postprandial antral hypomotility in childhood.  Pediatrics 90.
• Ordein JJ, Di Lorenzo C, Flores AF, Hyman PE. 1992. Diversion colitis in children with severe gastrointestinal motility disorders.  Am J Gastroenterol 87.
• Dooley CP, Di Lorenzo C, Valenzuela JE. 1992. Variability of the motor migrating complex in the human.  Dig Dis Sci 37.
• Di Lorenzo C, Flores AF, Hyman PE. 1991. Intestinal motility in symptomatic children after fundoplication.  J Pediatr Gastroenterol Nutr 12.
• Di Lorenzo C, Dooley CP, Valenzuela JE. 1991. Role of fasting gastrointestinal motility in the variability of gastrointestinal transit time assessed by hydrogen breath test.  Gut 32.
• Di Lorenzo C, Grill BB, Hyman PE. 1991. Pediatric application of pH monitoring. In Ambulatory esophageal pH monitoring: Practical approach and clinical applications. New York: Igaku-Shoin Medical Pub.
• Di Lorenzo C, Reddy SN, Villanueva-Meyer J, Mena I, Martin S, Hyman PE. 1991. Cisapride in children with chronic intestinal pseudo-obstruction.  Gastroenterology 101.
• Di Lorenzo C, Lachman R, Hyman P. 1990. Intravenous erythromycin for postpyloric intubation.  J Pediatr Gastroenterol Nutr 11.
• Cadranel S, Di Lorenzo C, Piepsz A, Ham HR. 1990. Esophageal function in children after caustic ingestion.  J Pediatr Gastroenterol Nutr 10.
• Dooley C, Di Lorenzo C, Valenzuela J. 1990. Esophageal function in humans: effects of bolus consistency and temperature.  Dig Dis Sci 35.
• Rezende J, Di Lorenzo C, Dooley C, Valenzuela JE. 1989. Cisapride stimulates antral motility and decreases duodenogastric reflux.  Dig Dis Sci 34.
• Di Lorenzo C, Dooley C, Valenzuela JE. 1989. Response of lower esophageal sphincter to alteration of intra-abdominal pressure.  Dig Dis Sci 34.
• Cadranel S, Di Lorenzo C, Rodesch P, Piepsz A, Ham PR. 1988. Caustic ingestion and esophageal function.  Z Kinderchir 43.
• Cucchiara S, Staiano A, Di Lorenzo C, Auricchio S. 1988. Mechanisms of gastroesophageal reflux and distal esophageal motility in children with GER disease.  J Pediatr Gastroenterol Nutr 7.
• Cucchiara S, Di Lorenzo C, Basile P. 1988.  Disordini della motilia' digestiva.
• Cucchiara S, Di Lorenzo C,. 1988. I disturbi della motilita' delle alte vie digerenti.  Prospettive in Pediatria 71.
• Di Lorenzo C, Williams C, Hajnal F, Valenzuela JE. 1988. Pectin delays gastric emptying and induces satiety in obese objects.  Gastroenterology 95.
• Cucchiara S, Di Lorenzo C, Basile P. 1988.  Disordini della motilita' digestiva.
• Cucchiara S, Staiano A, Capozzi C, Di Lorenzo C, Boccieri A, Auricchio S. 1987. Cisapride for gastroesophageal reflux and peptic esophagitis.  Arch Dis Child.
• Cadranel S, Di Lorenzo C, Rodesch P. 1987. Gastroesophageal reflux in pediatric patients: studies with alizapride.  Pharmacotera 5.
• Di Lorenzo C, Piepsz A, Ham HR, Cadranel S. 1987. Gastroesophageal reflux and gastric emptying.  Arch Dis Child 62.
• Cucchiara S, Staiano A, Di Lorenzo C, D'Ambrosio R, Andreotti MR, Auricchio S. 1986. Return of peristalsis in a child with esophageal achalasia treated by Heller's myotomy.  J Pediatr Gastroenterol Nutr 5.
• Cucchiara S, Staiano A, Di Lorenzo C, D'Ambrosia R, Andreotti MR, Prato M, De Filippo P, Auricchio S. 1986. Esophageal motor abnormalities in children with gastroesophageal reflux and peptic esophagitis.  J Pediatr 108.
• Cucchiara S, Tamburrini O, Staiano A, Devizia O, Corazziari E, Di Lorenzo C, Pellegrino M, Auricchio S. 1984. Approccio diagnostico alla stipsi in eta' pediatrica.  Ital J Ped 10.
• Cucchiara S, Coremans G, Staiano A, Corazziari E, Di Lorenzo C, Tamburrini O, Auricchio S. 1984. Gastrointestinal transit time and anorectal manometry in children with fecal soiling.  J Pediatr Gastroenterol Nutr 3.
• Sood MR, Mousa H, Tipnis N, Di Lorenzo C, Werlin S, Fernandez S, Liem O, Simpson P, Rudolpj C. Inter-Observer Variability In The Interpretation Of Colon Manometry Studies in Children.  Journal of Pediatric Gastroenterology and Nutrition.

• Board Member, United Mitochondrial Disease Foundation
• Chairman, Pediatric Slide Committee for the Rome III Initiative
• Council Member, Functional Bowel Group (FBG)
• Grant Reviewer, Thrasher Research Fund
• Invited Professor, PhD thesis for Dr. Maartje van Den Berg, Amsterdam, The Netherlands and Dr. Ilse Hoffman, Leuven, Belgium
• Listed, Best Doctors in America
• Member, Board for the "Small Intestine" section Faculty of 1000 Medicine
• Member, Clinical Practice Committee of the American Motility Society
• Member, Editorial Boards of Journal of Pediatric Gastroenterology and Nutrition and Journal of Neurogastroenterology and Motility
• Member, Functional GI Disorders & Motility Disorders Working Group of the National Commission on Digestive Diseases (NCDD) of the NIH
• Member, GI Working Group for “America’s Best Children’s Hospitals” for U.S.News & World Report
• Member, Scientific Advisory Board (SAB) of the Children’s Digestive Health and Nutrition Foundation (CDHNF)
• Member, Scientific Advisory Board of the University of North Carolina (UNC) Center for Functional GI and Motility Disorders
• Member, Sub-board of Pediatric Gastroenterology of the American Board of Pediatrics (ABP)