Benjamin T. Kopp, MD :: Nationwide Children's Hospital, Columbus, Ohio
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Benjamin T. Kopp, MD

Benjamin T. Kopp, MD

Asthma Program
Physician Team

Center for Microbial Pathogenesis
Principal Investigator

Cystic Fibrosis
Physician Team

Pediatric Pulmonary Fellowship

Pulmonary Medicine
Physician Team

Contact Information

Pulmonary Medicine
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-4766
FX: (614) 722-4755

Location Information for Patients

Main Campus


Benjamin T. Kopp, MD, is a member of the Section of Pulmonary Medicine and a principal investigator for the Center for Microbial Pathogenesis. Dr. Kopp started one of the country’s only pediatric Pulmonary/Sickle Cell combination clinics to treat Sickle Cell Lung Disease in a multi-disciplinary clinic. He is also a member of the Cystic Fibrosis Team and an assistant professor of Pediatrics for The Ohio State University College of Medicine. Dr. Kopp received his undergraduate degree from Miami University, Oxford, Ohio, and went to medical school at The Ohio State University College of Medicine. He completed his residency and fellowship in pediatric pulmonology at Nationwide Children’s Hospital. Dr. Kopp’s research interest involves therapies for cystic fibrosis including early disease mechanisms and improving clearance of chronic bacterial infections (b.cenocepacia), as well as preventing chronic lung disease in patients with Sickle Cell.

View CV »


  • Male

Languages Spoken:

  • English

Research Interests

Research Center:

Areas of Interest:

  • Macrophage autophagy and its role in controlling infection
  • Translational cystic fibrosis (CF) research focused on host-pathogen interactions and control of chronic infections (Burkholderia species, etc.)
  • Co-morbid conditions that impact inflammation in CF (secondhand smoke, depression)
  • Risk factors for Sickle Cell lung disease

Education and Training

Medical School

  • Ohio State University College of Medicine
    Date Completed: 06/11/2006


  • Nationwide Children's Hospital
    Date Completed: 06/30/2009


  • Nationwide Children's Hospital
    Date Completed: 06/30/2012


  • Pediatrics


  • Pulmonary Medicine


  • Pediatric Pulmonary Medicine
  • Pediatrics

Date of Appointment at Nationwide Children’s Hospital:

  • 11/30/2010


  • Kopp,Benjamin,T; Sarzynski,Lisa; Khalfoun,Sabrina; Hayes,Don; Thompson,Rohan; Nicholson,Lisa; Long,Frederick; Castile,Robert; Groner,Judith. 2015. Detrimental Effects of Secondhand Smoke Exposure on Infants With Cystic Fibrosis.  PEDIATRIC PULMONOLOGY. Vol. 50, no. 1. (January): 25-34.
  • Hayes,Don; Daniels,Curt,J; Kirkby,Stephen; Kopp,Benjamin,T; Nicholson,Kerri,L; Nance,Ashley,E; Splaingard,Mark,L. 2014. Polysomnographic Differences Associated with Pulmonary Hypertension in Patients with Advanced Lung Disease Due to Cystic Fibrosis.  LUNG. Vol. 192, no. 3. (June): 413-419.
  • Hayes,Don; Naguib,Aymen; Kirkby,Stephen; Galantowicz,Mark; McConnell,Patrick,I; Baker,Peter,B; Kopp,Benjamin,T; Lloyd,Eric,A; Astor,Todd,L. 2014. Comprehensive evaluation of lung allograft function in infants after lung and heart-lung transplantation.  journal of heart and lung transplantation. Vol. 33, no. 5. (May): 507-513.
  • Assani,Kaivon; Tazi,Mia,F; Amer,Amal,O; Kopp,Benjamin,T. 2014. IFN-gamma Stimulates Autophagy-Mediated Clearance of Burkholderia cenocepacia in Human Cystic Fibrosis Macrophages.  PLOS ONE. Vol. 9, no. 5. (May): ee96681.
  • Limoli,Dominique,H; Rockel,Andrea,B; Host,Kurtis,M; Jha,Anuvrat; Kopp,Benjamin,T; Hollis,Thomas; Wozniak,Daniel,J. 2014. Cationic antimicrobial peptides promote microbial mutagenesis and pathoadaptation in chronic infections.  PLoS pathogens. Vol. 10, no. 4. (April): ee1004083.
  • Hayes,Don; Kopp,Benjamin,T; Kirkby,Stephen; Allen,Elizabeth,D; McCoy,Karen,S. 2014. Attrition in Pediatric Pulmonology Fellowship.  PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY. Vol. 27, no. 1. (March): 34-35.
  • Hayes,Don; Kopp,Benjamin,T; Preston,Thomas,J; Kirkby,Stephen; Tobias,Joseph,D; Papadimos,Thomas,J; Whitson,Bryan,A. 2014. Survival of patients with cystic fibrosis on ECMO: analysis of the Extracorporeal Life Support Organization Registry.  INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE. Vol. 7, no. 5. (January): 1370-1372.
  • Turner,Tiffany,L; Kopp,Benjamin,T; Paul,Grace; Landgrave,Lindsay,C; Hayes,Don; Thompson,Rohan. 2014. Respiratory syncytial virus: current and emerging treatment options.  ClinicoEconomics and outcomes research : CEOR. Vol. 6, no. January: 217-225.
  • Hayes,Don; Baker,Peter,B; Kopp,Benjamin,T; Kirkby,Stephen; Galantowicz,Mark; McConnell,Patrick,I; Astor,Todd,L. 2013. Surveillance transbronchial biopsies in infant lung and heart-lung transplant recipients.  PEDIATRIC TRANSPLANTATION. Vol. 17, no. 7. (November): 670-675.
  • Kopp,Benjamin,T; Kirkby,Stephen; Hayes,Don; Flanigan,Kevin,M. 2013. Diabetic myonecrosis in a cystic fibrosis patient.  Respiratory care. Vol. 58, no. 10. (October): e123-5.
  • Kopp,Benjamin,T; Hayes,Don; Ratkiewicz,Mia; Baron,Nancy; Splaingard,Mark. 2013. Light exposure and depression in hospitalized adult patients with cystic fibrosis.  JOURNAL OF AFFECTIVE DISORDERS. Vol. 150, no. 2. (September): 585-589.
  • Hayes,Don; Daniels,Curt,J; Mansour,Heidi,M; Kopp,Benjamin,T; Yates,Andrew,R; McCoy,Karen,S; Patel,Alpa,V; Kirkby,Stephen. 2013. Right heart catheterization measuring central hemodynamics in cystic fibrosis during exercise.  Respiratory medicine. Vol. 107, no. 9. (September): 1365-1369.
  • Meadows,John,T; Kopp,Benjamin,T; Shook,Lori,A; Ballard,Hubert,O; Hayes,Don. 2013. Elevated high-sensitivity C-reactive protein in preterm infants with pulmonary colonization with Ureaplasma.  JOURNAL OF THORACIC DISEASE. Vol. 5, no. 3. (June): 223-227.
  • Hayes D Jr, Ramanathan C, Kopp B. 2012. "BMPR2 missense mutation p.K230N and pulmonary arterial hypertension".  Pediatric Pulmonology 2012 Nov 8.. Vol. epub, no. November: eepub.
  • Kopp B, Rosen K, O'Donovan J, Sheikh S. 2012. "Cardiac fibroma, anomalous pulmonary venous course and persistent pneumonia in a patient with Gorlin syndrome".  Pediatric Pulmonology. Vol. epub, no. November: eepub.
  • Kopp,Benjamin,T; Abdulrahman,Basant,A; Khweek,Arwa,A; Kumar,Surender,B; Akhter,Anwari; Montione,Richard; Tazi,Mia,F; Caution,Kyle; McCoy,Karen; Amer,Amal,O. 2012. Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Vol. 424, no. 2. (July): 221-227.
  • Abdulrahman,Basant,Ahmed; Abu Khweek,Arwa; Caution,Kyle; Akhter,Anwari; Tazi,Mia; Kopp,Benjamin; Amer,Amal. 2012. Autophagy Stimulation Manipulates Burkholderia cenocepacia Infection in a Cystic Fibrosis Mouse Model. In Experimental Biology Meeting 2012
  • Kopp,Benjamin,T; Wang,Wei; Chisolm,Deena,J; Kelleher,Kelly,J; McCoy,Karen,S. 2012. Inpatient Healthcare Trends Among Adult Cystic Fibrosis Patients in the U.S.  PEDIATRIC PULMONOLOGY. Vol. 47, no. 3. (March): 245-251.
  • Abdulrahman,Basant,A; Abu Khweek,Arwa; Akhter,Anwari; Caution,Kyle; Kotrange,Sheetal; Abdelaziz,Dalia,HA; Newland,Christie; Rosales-Reyes,Roberto; Kopp,Benjamin; McCoy,Karen; Montione,Richard; Schlesinger,Larry,S; Gavrilin,Mikhail,A; Wewers,Mark,D; Valvano,Miguel,A; Amer,Amal,O. 2011. Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.  AUTOPHAGY. Vol. 7, no. 11. (November): 1359-1370.
  • Kopp,Benjamin,T; Pastore,Matthew,T; Sturm,Amy,C; Holtzlander,Melissa,J; Westman,Judith,A. 2011. A Novel Exon Duplication of the Cystic Fibrosis Transmembrane Conductance Regulator in a Patient Presenting With Adult-Onset Recurrent Pancreatitis.  PANCREAS. Vol. 40, no. 5. (July): 773-777.
  • Kotrange,Sheetal; Kopp,Benjamin; Akhter,Anwari; Abdelaziz,Dalia; Abu Khweek,Arwa; Caution,Kyle; Abdulrahman,Basant; Wewers,Mark,D; McCoy,Karen; Marsh,Clay; Loutet,Slade,A; Ortega,Ximena; Valvano,Miguel,A; Amer,Amal,O. 2011. Burkholderia cenocepacia O polysaccharide chain contributes to caspase-1-dependent IL-1 beta production in macrophages.  JOURNAL OF LEUKOCYTE BIOLOGY. Vol. 89, no. 3. (March): 481-488.
  • KOPP,B,T; Wang,W; Chisolm,D; Kelleher,K; McCoy,K. 2011. Inpatient Health Care Trends Among Adult Cystic Fibrosis Patients In The U.S.
  • Kopp B, Kirkby S, Hayes D, Flanigan K. "Diabetic myonecrosis in cyscit fibrosis patient.".  Respiratory Care 2013 Jan 29.
  • Kopp B, Hayes D, Ratkiewicz M, Baron N, Splaingard M. "Light exposure and depression in hospitalized adults with cystic fibrosis.".  J Affective Disorders 2013.
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700 Children's Drive Columbus, Ohio 43205 614.722.2000