Adult Congenital Heart Disease Fellowship Research :: Nationwide Children's Hospital, Columbus, Ohio

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Adolescent & Adult Congenital Heart Disease Program

Phone: (614) 722-5622

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Adult Congenital Heart Research


Feinstein JA, Benson DW, Dubin AM, Cohen MS, Maxey DM, Mahle WT, Pahl E, Villafañe J, Bhatt AB, Peng LF, Johnson BA, Marsden AL, Daniels CJ, Rudd NA, Caldarone CA, Mussatto KA, Morales DL, Ivy DD, Gaynor JW, Tweddell JS, Deal BJ, Furck AK, Rosenthal GL, Ohye RG, Ghanayem NS, Cheatham JP, Tworetzky W, Martin GR. Hypoplastic left heart syndrome; current considerations and expectations. J Am Coll Cardiol. 2012 Jan 3; 59(1 Suppl):S1-42. Review.

Crandall MA, Daoud EG, Daniels CJ, Kalbfleisch SJ. Percutaneous radiofrequency catheter ablation for atrial fibrillation prior to atrial septal defect closure. J Cardiovasc Electrophysiol. 2012 Jan; 23(1) 102-4.


Fernandes, S. M., Verstappen, A., Ackerman, K., Adam, E. E., Barton, C., Breitinger, P., Crumb, S., Adult Congenital Cardiac Care Associate Research Network.  Parental knowledge regarding lifelong congenital cardiac care. Pediatrics. 2011; 128: e1489-1495.

Tsai S, Daniels CJ. Are Guidelines Recommending Primary Echocardiography Adequate to Screen for Aortic Complications in Patients with Bicuspid Aortic Valve?  Congenital Heart Disease. E pub in press. 2011.

Tsai S, Trivedi M, Boettner B, Daniels CJ. Usefulness of screening cardiovascular MRI to detect aortic abnormalities after repair of COA. Am J Cardiol. 2011 Jan 15; 107(2):297-301.

Crumb SR, Cook SC, Cheatham JP, Galantowicz M, Feltes TF, Phillips A, Chan DP, Holzer RJ, Sisk M, Olshove V, Cook LR, Hickey JC, Hill SL, Daniels CJ. Quality outcomes of ACHD patients undergoing cardiovascular procedures and hospital admissions in a free standing children’s hospital. Int J Cardiol. 2011 Feb 3; 146(3):326-9.

Smith JS, Mueller J, Daniels CJ. Pulmonary arterial hypertension in the setting of pregnancy; A case series and standard treatment approach. Lung. 2011 Dec 3. Epub.

Winner MW 3rd, Raman SV, Chung YC, Simonetti OP, Mihai G, Cook SC. Post- interventional three dimensional dark blood MRI in the adult with congenital heart disease. Int J Cardiol. 2011 Feb 9.

Zaidi AN, Bauer JA, Michalsky MP, Olshove V, Boettner B, Phillips A, Cook SC. Impact of obesity on early post-operative outcomes in adults with congenital heart. Cong Heart Dis. 2011 May-Jun; 6(3):241-6


Tsai, SF, Chan, DP, Ro, PS, Boettner, B, & Daniels, CJ. Rate of inducible ventricular arrhythmias in adults with congenital heart disease.  Am J Cardiol 2010; 106:730–6.

Moiduddin, N, Texter, Km, Zaidi, AN, Hershenson, JA, Stefaniak, C, Hayes, J, & Cua, CL. Two-dimensional speckle strain and dyssynchrony in single left ventricles vs. normal left ventricles. Congenital heart disease, 2010 Nov-Dec; 5(6): 579-86.

Hershenson, JA, Zaidi, AN, Texter, KM, Moiduddin, N, Stefaniak, C, Hayes, J, & Cua, CL.  Differences in tissue Doppler imaging between single ventricles after the Fontan operation and normal controls.  American Journal of Cardiology, 2010; 106(1): 99-103.

Moiduddin, N, Texter, Km, Zaidi, AN, Hershenson, JA, Stefaniak, C, Hayes, J, & Cua, CL.  Two-dimensional speckle strain and dyssynchrony in single right ventricles versus normal right ventricles.  Journal of the American Society of Echocardiography, 2010; 23(6): 673-9.

Grant Funded Projects

REACH: A Clinical-Research Information System for Adult Congenital Heart Disease: Facilitating Research Through Automated Electronic Integration of Data Sources
Principal Investigator: Ali N Zaidi, MD
NIH Funded / Oregon Health Science University
Collaboration with Boston Children’s Hospital, OHSU, Cincinnati Children’s, Wisconsin Children’s and Nationwide Children’s Hospital.

Illness Knowledge and Self-Management for Adolescents, Emerging Adults, and Adults with Congenital Heart Disease.
IRB approved
Principal Investigator: Jamie Jackson, PhD (Clinical Psychology)
Recruitment began April 2012
NIH T 32 Training Grant
CRI Grant
Mentors: Curt J Daniels MD, Kathy Vannatta, PhD,

Assessment of the Genetic Knowledge of Adolescents and Young Adults with Congenital Heart Defects and their Parents
IRB approved
Principal Investigator: Sara Fitzgerald Butt, PhD (Clinical Genetics)
Recruitment in began in April 2012
2012 Jane Engelberg Memorial Fellowship, an annual grant from the Engelberg Foundation to the National Society of Genetic Counselors, Inc.
Collaboration with: Vidu Garg MD, Sara Fitzgerald-Butt PhD, Ali N Zaidi, MD

Assessing the Cardiac, Obstetric and Anesthetic Risk and Outcomes of Pregnant Women with Adult Congenital Heart Disease – A single center experience.
Pregnancy database created
Data entry using REDCap data entry software
> 500 women with CHD enrolled
IRB approved (reciprocity b/w OSU and NCH)
Principal Investigator: Ali N Zaidi, MD, with multiple collaborators
Intramural grant funding

Ongoing projects

Cognitive Impairment and Psychological Impairment in the Adult Congenital Heart Disease (ACHD) Population
IRB approved
Principal Investigator: Ali N. Zaidi
Recruitment in fall 2012
Screening for cognitive impairment, anxiety and depression
Blood collection for DNA bank
Collaboration with Vidu Garg MD, Sara Fitzgerald-Butt PhD, Kim McBride MD, Cathy Butz, PhD and Ali N Zaidi, MD

Multi center pulmonary hypertension in ACHD registry
Multi-center ACHD Eisenmenger patient registry


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700 Children's Drive Columbus, Ohio 43205 614.722.2000